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Development and clinical application fo 4DCG for neurosurgical simulation

Research Project

Project/Area Number 18K08938
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 56010:Neurosurgery-related
Research InstitutionThe University of Tokyo

Principal Investigator

Kin Taichi  東京大学, 医学部附属病院, 助教 (90447392)

Project Period (FY) 2018-04-01 – 2021-03-31
Project Status Completed (Fiscal Year 2020)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2020: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2019: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2018: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Keywords脳神経外科 / 流体解析 / 4DCG / 手術シミュレーション / 血流解析 / PC-MRA / TOF-MRA / 正規化相互情報量法 / 脳血管 / 4DCG / バーチャルリアリティ
Outline of Final Research Achievements

The researcher developed a novel method using four-dimensional computer graphics and verified its clinical usefulness. The schedule was achieved as planned and there was no delay in the research. The researcher has developed a new fusion method between phase-contrast magnetic resonance imaging and medical fusion three-dimensional computer graphics. In particular, there were remarkable results that the researcher found a method that can estimate the wall thickness of the cerebral aneurysm, and a significant difference in blood flow analysis between the ruptured group and non-ruptured group in cerebral arteriovenous malformation. Both of results were submitted to international journal.

Academic Significance and Societal Importance of the Research Achievements

学術的意義としては、生体データにおけるスカラーとベクトルの位置合わせ手法を確立したことである。本法はスカラー形状とベクトルとの中心領域をレジストレーションするものであり、これは管腔構造を流れる層流の特性を反映している理論的整合性の高いものである。また、本法は医療以外のあらゆる流体解析へ応用できる可能性がある。in vivoデータと仮想データの融合方法を開発したという点でも研究意義が高い。社会的意義としては、提案手法によってこれまで不可能とされてきた複雑な形状を有する疾患への時空間的な流体解析が可能となり、病態解明、治療効果判定、および手術検討への有用性が示唆されたことである。

Report

(4 results)
  • 2020 Annual Research Report   Final Research Report ( PDF )
  • 2019 Research-status Report
  • 2018 Research-status Report
  • Research Products

    (12 results)

All 2021 2020 2019 2018

All Journal Article (2 results) (of which Peer Reviewed: 2 results,  Open Access: 2 results) Presentation (10 results) (of which Int'l Joint Research: 1 results,  Invited: 3 results)

  • [Journal Article] Registration Method Between Phase-Contrast Magnetic Resonance Angiography and Time-of-Flight Magnetic Resonance Angiography―A Preliminary Study2021

    • Author(s)
      Seiji Nomura, Taichi Kin, Akira Kunimatsu, Masaaki Shojima, Yasushi Watanebe, Yuuichi Suzuki, Naoyuki Shono, Hideaki Imai, Toki Saito, Hirofumi Nakatomi, Hiroshi Oyama, Nobuhito Saito
    • Journal Title

      Journal of Medical Imaging and Health Informatics

      Volume: 11 Pages: 1-7

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Correlation of Inflow Velocity Ratio Detected by Phase Contrast Magnetic Resonance Angiography with the Bleb Color of Unruptured Intracranial Aneurysms2020

    • Author(s)
      Hiroki Uchikawa, Taichi Kin, Yasuhiro Takeda, Tsukasa Koike, Satoshi Kiyofuji, Satoshi Koizumi, Taketo Shiode, Yuichi Suzuki, Satoru Miyawaki, Hirofumi Nakatomi, Akitake Mukasa, Nobuhito Saito
    • Journal Title

      World Neurosurgery X

      Volume: in press Pages: 100098-100098

    • DOI

      10.1016/j.wnsx.2021.100098

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Presentation] 脳腫瘍の術前シミュレーション2020

    • Author(s)
      金太一
    • Organizer
      第43回日本脳神経CI学会総会
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] アプリで学ぶCGシミュレーション時代の脳幹解剖2020

    • Author(s)
      金太一
    • Organizer
      第40回日本脳神経外科コングレス総会
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] 手術シミュレーションのイノベーション2020

    • Author(s)
      金太一
    • Organizer
      第79回日本脳神経外科学会総会
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] AI技術を用いた医用融合3次元画像作成ソフトウェアの開発と臨床応用2019

    • Author(s)
      金太一
    • Organizer
      第24回日本脳腫瘍外科学会
    • Related Report
      2019 Research-status Report
  • [Presentation] 3D Phase-contrast MRIを用いた破裂脳動静脈奇形の定量的血流解析及び未破裂例との比較検討2019

    • Author(s)
      武田康寛
    • Organizer
      3D Phase-contrast MRIを用いた破裂脳動静脈奇形の定量的血流解析及び未破裂例との比較検討
    • Related Report
      2019 Research-status Report
  • [Presentation] Presurgical strategic simulation of giant thrombosed fusiform aneurysms with 3D fusion images2019

    • Author(s)
      清藤哲史
    • Organizer
      2019 ASEAN Neurosurgical conference, Hanoi, Vietnam
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] 神経膠腫における複合現実技術を用いた言語野と拡散テンソルトラクトグラフィーの検証2019

    • Author(s)
      小池司
    • Organizer
      第37回日本脳腫瘍学会
    • Related Report
      2019 Research-status Report
  • [Presentation] Phase Contrast MRAを用いた脳動脈瘤の血流解析2019

    • Author(s)
      内川裕貴
    • Organizer
      第78回日本脳神経外科学会学術集会
    • Related Report
      2019 Research-status Report
  • [Presentation] 仮想空間と実空間の情報融合による手術支援2018

    • Author(s)
      小池司
    • Organizer
      第18回日本VR医学会学術大会
    • Related Report
      2018 Research-status Report
  • [Presentation] テクスチャマッピング法を用いた仮想空間と実空間の情報融合による脳神経外科手術支援2018

    • Author(s)
      小池司
    • Organizer
      第23回日本脳腫瘍の外科学会
    • Related Report
      2018 Research-status Report

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Published: 2018-04-23   Modified: 2022-01-27  

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