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Related factors of cellulitis history in lymphoedema patients

Research Project

Project/Area Number 18K10307
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 58060:Clinical nursing-related
Research InstitutionFujita Health University (2021-2022)
The University of Tokyo (2019-2020)
Kanazawa University (2018)

Principal Investigator

Dai Misako  藤田医科大学, 社会実装看護創成研究センター, 准教授 (50614864)

Project Period (FY) 2018-04-01 – 2023-03-31
Project Status Completed (Fiscal Year 2022)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2022: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2021: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2020: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2019: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2018: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywordsリンパ浮腫 / 蜂窩織炎 / 超音波検査技術 / 細菌叢 / 超音波画像診断 / 細菌叢解析 / エコー / 再発リスク / 蜂窩織炎再発 / マルチオミックス解析 / 皮膚免疫機能 / 皮膚構造
Outline of Final Research Achievements

Recurrent cellulitis has high impact on physical, psychological, and social aspects for lymphedema patients. We speculated that identification of characteristics of skin and subcutaneous adipose tissue with cellulitis history can help considering new approach for prevention of recurrent cellulitis in lymphedema patients. Therefore, as the main topic in this study, we aimed to noninvasively identify the ultrasonographic features of skin and subcutaneous tissue of lymphedema in patients with a cellulitis history. In this study, cellulitis history in lymphedema patients appears to be associated with dermal hypoechogenicity, particularly in the proximal lower extremity. This finding suggests that it may be the initial step to consider new approach for prevention of recurrent cellulitis in lymphedema patients.

Academic Significance and Societal Importance of the Research Achievements

まず、本研究では、リンパ浮腫患者の蜂窩織炎再発に着目し、蜂窩織炎既往歴を有する者の真皮のエコー所見特徴を明らかにした点で、これまで臨床で難渋していた蜂窩織炎再発予防を検討するステップとなったと考えられ学術的意義が高いといえる。エコーは非侵襲的・リアルタイム・簡便に使用可能な機器で、今後、リンパ浮腫管理に導入・普及することが望まれる。将来的には本研究で明らかにしたエコー所見を用いてリンパ浮腫管理の有効性が明らかになることで、蜂窩織炎再発予防に向けた新たな評価方法の提案、管理方法の検討へとつながり、患者らの生活の質向上が期待できる点で社会的意義が高いといえる。

Report

(6 results)
  • 2022 Annual Research Report   Final Research Report ( PDF )
  • 2021 Research-status Report
  • 2020 Research-status Report
  • 2019 Research-status Report
  • 2018 Research-status Report
  • Research Products

    (25 results)

All 2022 2021 2020 2019 2018 Other

All Int'l Joint Research (2 results) Journal Article (6 results) (of which Int'l Joint Research: 2 results,  Peer Reviewed: 6 results,  Open Access: 4 results) Presentation (14 results) (of which Int'l Joint Research: 8 results,  Invited: 7 results) Remarks (3 results)

  • [Int'l Joint Research] University of Nottingham(英国)

    • Related Report
      2021 Research-status Report
  • [Int'l Joint Research] モンペリエ大学(フランス)

    • Related Report
      2018 Research-status Report
  • [Journal Article] Real-time image-sharing education for self-care to wearing elastic stockings in a lymphoedema patient: A case study.2022

    • Author(s)
      Dai M, Yamashita S, Okazaki M, Kimori K, Sanada H, Sugama J.
    • Journal Title

      Br J Nurs.

      Volume: 31 Issue: 15 Pages: S22-S29

    • DOI

      10.12968/bjon.2022.31.15.s22

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Association Between Access to Specialists and History of Cellulitis Among Patients with Lymphedema: Secondary Analysis Using the National LIMPRINT Database2021

    • Author(s)
      Dai Misako、Nakagami Gojiro、Sato Aya、Koyanagi Hiroe、Kohta Masushi、Moffatt Christine J.、Murray Susie、Franks Peter J.、Sanada Hiromi、Sugama Junko
    • Journal Title

      Lymphatic Research and Biology

      Volume: 19 Issue: 5 Pages: 442-446

    • DOI

      10.1089/lrb.2021.0056

    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Association of Dermal Hypoechogenicity and Cellulitis History in Patients with Lower Extremity Lymphedema: A Cross-Sectional Observational Study2021

    • Author(s)
      Dai Misako、Minematsu Takeo、Ogawa Yoshihiro、Kawamoto Atsuo、Nakagami Gojiro、Sanada Hiromi
    • Journal Title

      Lymphatic Research and Biology

      Volume: -- Issue: 4 Pages: 1-7

    • DOI

      10.1089/lrb.2021.0004

    • Related Report
      2021 Research-status Report
    • Peer Reviewed
  • [Journal Article] Subjective thermal sensation effect of cool feeling compression stocking for patients with lower limb lymphedema: A preliminary pre-post study2021

    • Author(s)
      Misako Dai, Takeo Minematsu, Yoshihiro Ogawa, Yuko Takanishi, Junko Sugama, Hiromi Sanada
    • Journal Title

      Journal of Japanse Society Wound, Ostomy, and Continence Management

      Volume: 25 Pages: 10-17

    • NAID

      130008009870

    • Related Report
      2021 Research-status Report
    • Peer Reviewed
  • [Journal Article] The Prevalence and Functional Impact of Chronic Edema and Lymphedema in Japan: LIMPRINT Study2019

    • Author(s)
      Dai Misako、Nakagami Gojiro、Sugama Junko、Kobayashi Noriko、Kimura Emiko、Arai Yoko、Sato Aya、Mercier Gregoire、Moffatt Christine、Murray Susie、Sanada Hiromi
    • Journal Title

      Lymphatic Research and Biology

      Volume: 17 Issue: 2 Pages: 195-201

    • DOI

      10.1089/lrb.2018.0080

    • Related Report
      2019 Research-status Report 2018 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Validity of pocket ultrasound device to measure thickness of subcutaneous tissue for improving upper limb lymphoedema assessment2018

    • Author(s)
      Dai M, Shogenji M, Matsui K, Kimori K, Sato A, Maeba H, Okuwa M, Konya C, Sugama J, Sanada H
    • Journal Title

      LYMPHOEDEMA RESEARCH AND PRACTICE

      Volume: 6 (1) Pages: 10-23

    • DOI

      10.15010/LRAP.2018.10.03.15

    • ISSN
      2188-1375
    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] リンパ浮腫ケア選定のためのエコーアルゴリズムの考案と実装2022

    • Author(s)
      臺 美佐子,山下 修二,楊睿,間脇 彩奈,岡崎 睦,須釜 淳子.
    • Organizer
      第6回日本リンパ浮腫治療学会学術総会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 多職種連携における看護師の浮腫アセスメント2022

    • Author(s)
      臺 美佐子
    • Organizer
      第11回国際リンパ浮腫フレームワーク・ジャパン研究協議会学術集会
    • Related Report
      2022 Annual Research Report
    • Invited
  • [Presentation] Lymphedema severity classification using ultrasound imaging2022

    • Author(s)
      Misako Dai
    • Organizer
      WUWHS2022
    • Related Report
      2021 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Effectiveness of an educational intervention using real-time images to improve self-care behaviors in patients with lymphedema.2021

    • Author(s)
      Misako Dai,Takeo Minematsu,Shuji Yamashita,Mutsumi Okazaki,Hiromi Sanada.
    • Organizer
      The 9th Asia Pacific Enterostomal Therapy Nurse Association Conference
    • Related Report
      2021 Research-status Report
    • Int'l Joint Research
  • [Presentation] Expectations from using hand-held visualization tool for preventing the recurrence of cellulitis in lymphoedema management2021

    • Author(s)
      Misako Dai, Yoshihiro Ogawa, Takeo Minematsu, Hiromi Sanada, Junko Sugama
    • Organizer
      The 9th Asia Pacific Enterostomal Therapy Nurse Association Conference
    • Related Report
      2021 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] リンパ浮腫評価の標準化に向けたアウトカム調査:ILF-COM2021

    • Author(s)
      臺 美佐子,仲上豪二朗,小林 範子,佐藤 文,小柳 礼恵,光田 益士,真田 弘美,Christine Moffatt,須釜 淳子
    • Organizer
      第10回国際リンパ浮腫フレームワーク・ジャパン研究協議会学術集会
    • Related Report
      2021 Research-status Report
  • [Presentation] リンパ浮腫患者のセルフケア支援としての夏用弾性ストッキング開発成果と実装に向けた今後の展望2021

    • Author(s)
      臺 美佐子,小川 佳宏,高西 裕子,須釜 淳子
    • Organizer
      第5回リンパ浮腫治療学会学術集会
    • Related Report
      2021 Research-status Report
    • Invited
  • [Presentation] Ultrasonography for prediction of cellulitis in lymphoedema2021

    • Author(s)
      Misako Dai, Junko Sugama
    • Organizer
      10th International Lymphoedema Framework Conference
    • Related Report
      2021 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Association between access to specialists and history of cellulitis among lymphedema patients in Japan2021

    • Author(s)
      Misako Dai,Gojiro Nakagami,Aya Sato,Hiroe Koyanagi,Masushi Kohta,Hiromi Sanada,Junko Sugama
    • Organizer
      第41回日本看護科学学会学術集会
    • Related Report
      2021 Research-status Report
  • [Presentation] 蜂窩織炎再発リスクを有する下肢リンパ浮腫患者の真皮・皮下組織のエコー所見2020

    • Author(s)
      臺 美佐子, 峰松 健夫, 小川 佳宏, 河本 敦夫, 仲上 豪二朗, 真田 弘美
    • Organizer
      第8回看護理工学会学術集会
    • Related Report
      2020 Research-status Report
  • [Presentation] Lymphoedema outcome survey in Japan for international standardization: ILF-COM2019

    • Author(s)
      Misako Dai
    • Organizer
      The 8th Asia Pacific Enterostomal Therapy Nurse Association
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] ILF-COM report from Japan.2019

    • Author(s)
      Misako Dai
    • Organizer
      9th International Lymphoedema Framework Conference
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] The prevalence and quality of life in patients with chronic edema in Japan2019

    • Author(s)
      Misako Dai
    • Organizer
      第39回日本看護科学学会学術集会
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] Ultrasonography and thermography as new methods of assessing cellulitis with lymphedema.2018

    • Author(s)
      Dai M, Nakagami G, Minematsu T, Sugama J, Sanada H, Quere I.
    • Organizer
      8th International Lymphoedema Framework conference
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research / Invited
  • [Remarks] 藤田医科大学 社会実装看護創成研究センター

    • URL

      https://www.fujita-hu.ac.jp/faculty/implementation-nursing-sciences/gyouseki.html

    • Related Report
      2022 Annual Research Report
  • [Remarks] 藤田医科大学研究推進本部 社会実装看護創成研究センター

    • URL

      https://www.fujita-hu.ac.jp/faculty/implementation-nursing-sciences/

    • Related Report
      2021 Research-status Report
  • [Remarks] 東京大学大学院医学系研究科社会連携講座スキンケアサイエンス ホームページ

    • URL

      http://skincarescience.m.u-tokyo.ac.jp/publications.html

    • Related Report
      2019 Research-status Report

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Published: 2018-04-23   Modified: 2024-01-30  

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