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Whether exercise reduces advanced glycation end products (AGEs) and has an antiglycation effect

Research Project

Project/Area Number 18K10844
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 59020:Sports sciences-related
Research InstitutionKyoritsu Women's Junior College

Principal Investigator

Nakajima Sanae  共立女子短期大学, その他部局等, 教授 (60535459)

Co-Investigator(Kenkyū-buntansha) 古泉 佳代  日本女子体育大学, 体育学部, 准教授 (20637342)
Project Period (FY) 2018-04-01 – 2023-03-31
Project Status Completed (Fiscal Year 2022)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2020: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2019: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2018: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywords終末糖化産物 / AGEs / 運動 / 糖化 / 抗糖化
Outline of Final Research Achievements

To verify the usefulness of skin advanced glycation end products (AGEs) as a new indicator for physical condition management, the relationship between skin AGE levels and lifestyle, including diet and exercise, was investigated in young women. Results suggested that dietary intake corresponding to activity levels and coping with physical stress and fatigue are issues for young women. A medium-to-long-term survey and experiment were conducted to investigate the relationship with habitual exercise. However, because of the COVID-19 pandemic, the research plan was suspended and drastically changed. Therefore, we could not conduct our research to the stage that was set as our goal. Nonetheless, even during the COVID-19 crisis, we were able to obtain useful results that will serve as a reference for future research.

Academic Significance and Societal Importance of the Research Achievements

皮膚AGEs値は短期的な指標ではなく、2~3ヶ月前の状態を表す指標であり、運動や食事等の介入直後の変動を確認するような指標としては向いていない。しかしながら、蓄積するまでに時間を有する特性をいかし、習慣的な食事や運動による身体への影響を把握するための長期的なコンディショニングの指標としては簡便で日常的に有用できる可能性がある。生活習慣病予防および健康の維持・増進のための食事や運動の指導や、アスリートを対象とした食事の調整や蓄積する疲労状態のチェック等、体調管理に用いる新たな指標として幅広く活用することができる。

Report

(6 results)
  • 2022 Annual Research Report   Final Research Report ( PDF )
  • 2021 Research-status Report
  • 2020 Research-status Report
  • 2019 Research-status Report
  • 2018 Research-status Report
  • Research Products

    (7 results)

All 2022 2021 2020 2019 2018

All Presentation (7 results) (of which Int'l Joint Research: 4 results)

  • [Presentation] Changes in skin Advanced glycation end-products values of university students in Fitness & Sports classes2022

    • Author(s)
      Sanae Nakajima, Kayo Koizumi
    • Organizer
      European College of Sport Science (ECSS)2022
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Relationship between skin advanced glycation end product values and lifestyle habits of female college athletes during the period of self-restraint from going out2021

    • Author(s)
      Sanae Nakajima, Kayo Koizumi, Akari Miyachi, Yuna Maeda
    • Organizer
      the 26th Annual Congress of the European College of Sport Science: ECSS Virtual Congress 2021
    • Related Report
      2021 Research-status Report
    • Int'l Joint Research
  • [Presentation] The effect of transient exercise on the levels of advanced glycation end-products and related markers in young women2020

    • Author(s)
      Sanae Nakajima
    • Organizer
      European College of Sport Science 25nd ECSS Congress
    • Related Report
      2020 Research-status Report
    • Int'l Joint Research
  • [Presentation] Difference in Advance Glycation End-Products (AGEs) value of female college students with or without exercise habits2019

    • Author(s)
      Sanae Nakajima
    • Organizer
      23rd IUHPE World Conference on Health Promotion
    • Related Report
      2019 Research-status Report 2018 Research-status Report
  • [Presentation] 一過性の運動前後におけるAGEs値および血中HbA1C値の動態2019

    • Author(s)
      中島 早苗
    • Organizer
      日本体育学会第70回大会
    • Related Report
      2019 Research-status Report
  • [Presentation] 大学生女子アスリートを対象としたAGEs(Advance Glycation End-Products)値と身体的特徴および食習慣との関連性について2019

    • Author(s)
      中島 早苗, 古泉 佳代
    • Organizer
      日本体育学会第69回大会
    • Related Report
      2018 Research-status Report
  • [Presentation] Comparison of AGEs values and eating habits between regular female university students and athlete female university students2018

    • Author(s)
      Sanae Nakajima, Kayo Koizumi, Chuhwa CHO
    • Organizer
      European College Of Sport Science 23nd ECSS Congress
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research

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Published: 2018-04-23   Modified: 2024-01-30  

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