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Establishment of exercise indicator for lifestyle-related disease

Research Project

Project/Area Number 18K10876
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 59020:Sports sciences-related
Research InstitutionKawasaki Medical School

Principal Investigator

Nakanishi Shuhei  川崎医科大学, 医学部, 准教授 (70372183)

Project Period (FY) 2018-04-01 – 2022-03-31
Project Status Completed (Fiscal Year 2021)
Budget Amount *help
¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2020: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2019: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2018: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Keywords運動療法 / 2型糖尿病 / 生活習慣病
Outline of Final Research Achievements

Exercise is one of the important therapies for metabolic disorders. Accordingly, it requres specific and effective instruction for exercise to the patients. Finding of convenient markers for physical therapy on the treatment for metabolic disorders is an urgent issue. This research investigated key factors for exercise therapy. As results, we found that the combination of avoiding sedentary behavior as well as increasing physical activity might be important in the prevention bodyweight gain and in the avoidance of central obesity, respectively, in patients with type 2 diabetes. These results suggest that consideration of sedentary behavior in combination with daily walking steps might be essential for type 2 diabetes management.

Academic Significance and Societal Importance of the Research Achievements

本研究の結果、安静時間は運動強度よりもむしろより強く体重と関連し、同時にウエスト周囲径や内臓脂肪面積と関連した。以上の事から糖尿病をはじめとする生活習慣病の運動指導はその運動内容以上に如何に安静時間を減らすかに注目することが脂肪蓄積の量(体重)のみならず質(内臓脂肪蓄積)においても重要であり、単なる運動の奨励では限界があることを示したと考えられる。したがって、”運動するのが難しい”患者に対し指導を諦めるのではなく、”安静を減らす工夫を考える”ことも十分に意義があるあると考えられる。

Report

(5 results)
  • 2021 Annual Research Report   Final Research Report ( PDF )
  • 2020 Research-status Report
  • 2019 Research-status Report
  • 2018 Research-status Report
  • Research Products

    (5 results)

All 2021 2020 2019

All Journal Article (2 results) (of which Peer Reviewed: 2 results,  Open Access: 2 results) Presentation (3 results)

  • [Journal Article] Effects of sedentary behavior and daily walking steps on body mass index and body composition: Prospective observational study using outpatient clinical data of Japanese patients with type?2 diabetes2021

    • Author(s)
      Nakanishi Shuhei、Shimoda Masashi、Tatsumi Fuminori、Kohara Kenji、Obata Atsushi、Katakura Yukino、Sanada Junpei、Fushimi Yoshiro、Iwamoto Yuichiro、Onishi Mana、Isobe Hayato、Kusano Takashi、Dan Kazunori、Wamata Ryo、Iwamoto Hideyuki、Mune Tomoatsu、Kaku Kohei、Kaneto Hideaki
    • Journal Title

      Journal of Diabetes Investigation

      Volume: 12 Issue: 9 Pages: 1732-1738

    • DOI

      10.1111/jdi.13527

    • Related Report
      2021 Annual Research Report 2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Impact of physical activity and sedentary time on glycated hemoglobin levels and body composition: Cross‐sectional study using outpatient clinical data of Japanese patients with type?2 diabetes2019

    • Author(s)
      Nakanishi Shuhei、Hirukawa Hidenori、Shimoda Masashi、Tatsumi Fuminori、Kohara Kenji、Obata Atsushi、Okauchi Seizo、Katakura Yukino、Sanada Junpei、Fushimi Yoshiro、Nishioka Momoyo、Kan Yuki、Tomita‐Mizoguchi Akiko、Isobe Hayato、Iwamoto Hideyuki、Takahashi Kaio、Mune Tomoatsu、Kaku Kohei、Kaneto Hideaki
    • Journal Title

      Journal of Diabetes Investigation

      Volume: - Issue: 3 Pages: 633-639

    • DOI

      10.1111/jdi.13185

    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] 2型糖尿病の運動療法が体重および体組成に及ぼす効果は安静時間の影響を受けるか2021

    • Author(s)
      大西真奈、中西修平、辰巳文則、段和徳、草野峻、和又諒、磯辺隼人、岩本侑一郎、片倉幸乃、木村友彦、小畑淳史、小原健司、下田将司、宗友厚、加来浩平、金藤秀明
    • Organizer
      第64回日本糖尿病学会年次学術集会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 外来定期通院中の2型糖尿病患者の身体活動とウエストおよび内臓脂肪との関係2020

    • Author(s)
      岩本秀幸,菅勇貴,小原健司,下田将司,辰巳文則,片倉幸乃,岡内省三, 蛭川英典,小畑淳史,益子晃子,冨田明子,磯辺隼人,高橋快旺, 真田淳平,伏見佳朗,中西修平,宗友厚,加来浩平,金藤秀明
    • Organizer
      第63回日本糖尿病学会年次学術集会
    • Related Report
      2020 Research-status Report
  • [Presentation] 外来定期通院中の2型糖尿病患者の身体活動と血糖管理および体重の関係2019

    • Author(s)
      菅勇貴, 岡内省三, 辰巳文則, 小原健司, 下田将司, 中西修平, 宗友厚, 加来浩平, 金藤秀明
    • Organizer
      日本糖尿病学会中国四国地方会第57回総会
    • Related Report
      2019 Research-status Report

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Published: 2018-04-23   Modified: 2023-01-30  

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