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A study of new preventive strategies for type 2 diabetes based on genetic predisposition, lifestyle, social and environmental factors

Research Project

Project/Area Number 18K11046
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 59040:Nutrition science and health science-related
Research InstitutionShimane University

Principal Investigator

Takeda Miwako  島根大学, 地域包括ケア教育研究センター, 特例研究員 (70750644)

Co-Investigator(Kenkyū-buntansha) 濱野 強  京都産業大学, 現代社会学部, 教授 (80410257)
Project Period (FY) 2018-04-01 – 2022-03-31
Project Status Completed (Fiscal Year 2021)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2020: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2019: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2018: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywords2型糖尿病 / 遺伝素因 / 社会・環境要因 / ソーシャル・キャピタル / 暮らし向き / 糖尿病 / 環境要因 / 人間関係
Outline of Final Research Achievements

In this study, we examined whether social capital, meaning the degree of trust relationship and mutual aid within the region, influences type 2 diabetes considering lifestyle and genetic factors. As a result, there was no significant association between social capital and type 2 diabetes. We also examined the association between living status (feel richness or poverty) and type 2 diabetes. The probability of type 2 diabetes significantly increased among people who felt poverty, even after other factors are adjusted.
In the future, it is expected the research about various social and environmental factors that help prevention of type 2 diabetes.

Academic Significance and Societal Importance of the Research Achievements

本研究では,社会・環境要因の一つであるソーシャル・キャピタルが,生活習慣や遺伝素因を考慮しても、2型糖尿病に影響を与えるかどうか検証を行った。結果として双方の関連は認められなかったが,遺伝素因を踏まえた上で社会・環境要因がどのような影響を与えるかを検討することができた。同様の手法で,主観的な貧富感を示す「暮らし向き」との関連について解析したところ,苦しいと回答した者で2型糖尿病の確率に有意な上昇を認めた。このように今後,個人の多様な遺伝素因のみならず,多様な社会・環境要因についても解析を進めていくことで,どのような個人にどのような対策が有効か,予防プログラムの検討に役立つものと考える。

Report

(5 results)
  • 2021 Annual Research Report   Final Research Report ( PDF )
  • 2020 Research-status Report
  • 2019 Research-status Report
  • 2018 Research-status Report
  • Research Products

    (5 results)

All 2022 2021 2020 2018

All Journal Article (2 results) (of which Peer Reviewed: 2 results,  Open Access: 2 results) Presentation (3 results)

  • [Journal Article] Combined association of oral and skeletal muscle health with type 2 diabetes mellitus among community-dwelling older adults in Japan: a cross-sectional study2022

    • Author(s)
      Miwako Takeda, Takafumi Abe, Yuta Toyama, Kazumichi Tominaga, Shozo Yano, Toru Nabika, Masayuki Yamasaki
    • Journal Title

      Journal of Rural Medicine

      Volume: 17 Issue: 2 Pages: 67-72

    • DOI

      10.2185/jrm.2021-042

    • ISSN
      1880-487X, 1880-4888
    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Inconvenience of Living Place Affects Individual HbA1c Level in a Rural Area in Japan: Shimane CoHRE Study2021

    • Author(s)
      Fukuoka Rie、Takeda Miwako、Abe Takafumi、Yamasaki Masayuki、Kimura Shinji、Okuyama Kenta、Isomura Minoru、Nabika Toru
    • Journal Title

      International Journal of Environmental Research and Public Health

      Volume: 18 Issue: 3 Pages: 1147-1147

    • DOI

      10.3390/ijerph18031147

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] COVID-19流行下における2型糖尿病患者の心理的ストレスの要因に関する検討2022

    • Author(s)
      武田美輪子,並河徹,中野邦彦
    • Organizer
      第32回日本医学看護学教育学会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 中山間地在住高齢者における糖尿病に対する口腔と骨格筋指標の相加効果2020

    • Author(s)
      武田美輪子,濱野強,矢野彰三,山﨑雅之, 塩飽邦憲
    • Organizer
      第69回日本農村医学会学術総会
    • Related Report
      2020 Research-status Report
  • [Presentation] ソーシャル・キャピタルと糖尿病との関連について―中山間地域の高齢者を対象とした検討―2018

    • Author(s)
      武田美輪子、濱野強、山﨑雅之、矢野彰三、塩飽邦憲
    • Organizer
      第67回日本農村医学会学術総会
    • Related Report
      2018 Research-status Report

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Published: 2018-04-23   Modified: 2023-01-30  

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