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Polycomb group protein-mediated control of transcriptional reprogramming and priming in systemic plant immunity

Research Project

Project/Area Number 18K14437
Research Category

Grant-in-Aid for Early-Career Scientists

Allocation TypeMulti-year Fund
Review Section Basic Section 38060:Applied molecular and cellular biology-related
Research InstitutionNara Institute of Science and Technology

Principal Investigator

Tajima Yuri  奈良先端科学技術大学院大学, 先端科学技術研究科, 特任助教 (80771154)

Project Period (FY) 2018-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2019: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2018: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywordsシロイヌナズナ / 植物免疫 / プライミング / ポリコーム複合体 / エピジェネティクス / 免疫プライミング
Outline of Final Research Achievements

Local defense activation at the pathogen recognition sites leads to systemic acquired resistance (SAR) in plants. During and/or after SAR, subsets of defense-related genes are poised for faster/greater induction upon the subsequent stimulus, designated systemic defense priming. We previously showed that CLF, which is a histone H3K27 methyltransferase subunit of polycomb repressive complex 2 (PRC2), positively regulates systemic defense priming in Arabidopsis thaliana. This study showed that MEA, which is a seed-specific homolog of CLF, is induced in leaves upon defense activation and also positively regulates systemic defense priming. Local immunity is not impaired in prc2 mutant plants, pointing to a significant role of PRC2 in systemic defense priming. To reveal genome-wide dynamics of these histone modifications in the establishment of defense priming, currently we have been analyzing H3K4me3 and H3K27me3 profiles during SAR.

Academic Significance and Societal Importance of the Research Achievements

病原菌による農作物の減収は、現代の農業において解決すべき重要課題の一つである。その対策の一つとして病害抵抗性遺伝子を標的とした育種がこれまで行われてきている。しかし、一般に防御応答を増強すると植物生産が低下することや、病害抵抗性遺伝子による抵抗性打破が起こることから、他の手段が必要であると考えられる。免疫プライミングは植物生長を維持しながらも防御応答を増強・誘導可能であることから、有用な対策となりうる。プライミングの成立や制御に関わる分子基盤の一端を明らかにすることによって、持続可能な農業生産システム開発の一助になると考えられる。

Report

(3 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Research-status Report
  • Research Products

    (6 results)

All 2020 2019

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (5 results) (of which Int'l Joint Research: 1 results)

  • [Journal Article] Plant physiological and molecular mechanisms in cross-regulation of biotic-abiotic stress responses2020

    • Author(s)
      Yuri Tajima, Eliza Po-iian Loo, Yusuke Saijo
    • Journal Title

      Priming-Mediated Stress and Cross-Stress Tolerance in Crop Plants

      Volume: - Pages: 21-34

    • DOI

      10.1016/b978-0-12-817892-8.00002-7

    • ISBN
      9780128178928
    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Presentation] ポリコーム抑制複合体依存的に機能する植物免疫プライミング制御因子の同定2020

    • Author(s)
      田島由理・佐藤昌直・Eliza Po-Iian Loo・西條雄介
    • Organizer
      令和2年度日本植物病理学会大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Histone modification-mediated control of systemic defense priming in Arabidopsis thaliana2020

    • Author(s)
      Yi Ting Yeh, Yuri Tajima, Eliza Po-Iian Loo, Natsuki Shiraishi, Yusuke Saijo
    • Organizer
      第61回日本植物生理学会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Polycomb repressive complex 2 positively regulates systemic immunity and priming in Arabidopsis thaliana2019

    • Author(s)
      Yuri Tajima, Masanao Sato, Eva-Maria Reimer-Michalski, Eliza Po-iian Loo, Barbara Kracher, Franziska Turck, Yusuke Saijo
    • Organizer
      2019 IS-MPMI XVIII Congress
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] ポリコーム抑制複合体を介した植物免疫プライミング機構2019

    • Author(s)
      田島由理、Eva-Maria Reimer-Michalski、Eliza Loo Po-iian、Barbara Kracher、Franziska Turck、佐藤昌直、西條雄介
    • Organizer
      日本植物病理学会
    • Related Report
      2018 Research-status Report
  • [Presentation] A positive role for Polycomb repressive complex in systemic immunity and defense priming in Arabidopsis thaliana2019

    • Author(s)
      Yuri Tajima, Eva-Maria Reimer-Michalski, Eliza Po-Iian Loo, Barbara Kracher, Franziska Turck, Masanao Sato, Yusuke Saijo
    • Organizer
      日本植物生理学会
    • Related Report
      2018 Research-status Report

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Published: 2018-04-23   Modified: 2021-02-19  

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