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Evaluation of the mechanism of resistance acquisition by carbon/nitrogen control in plants according to the mode of infection of pathogens

Research Project

Project/Area Number 18K14728
Research Category

Grant-in-Aid for Early-Career Scientists

Allocation TypeMulti-year Fund
Review Section Basic Section 44030:Plant molecular biology and physiology-related
Research InstitutionRikkyo University

Principal Investigator

Maekawa Shugo  立教大学, 理学部, 助教 (80711209)

Project Period (FY) 2018-04-01 – 2022-03-31
Project Status Completed (Fiscal Year 2021)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2021: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2020: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2019: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2018: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords植物免疫 / 栄養応答 / C/N応答 / 細胞死 / シロイヌナズナ / 植物病理 / 植物栄養 / 炭素/窒素バランス
Outline of Final Research Achievements

This research was designed to elucidate an unknown method of plant resistance to pathogens. Our results suggest that spontaneous programmed cell death, an important resistance strategy against parasitic pathogens, is more likely to occur at higher carbon/nitrogen balance (C/N) levels. In contrast, the results suggest that a low C/N ratio is associated with higher resistance against necrotrophic pathogens. The analysis focusing on ribosome biosynthesis factors also supported a strong relationship between the C response and the ribosomal stress response. This research suggests that plant C/N is an important factor in disease response and that the ribosomal stress response is a factor that impacts the C response.

Academic Significance and Societal Importance of the Research Achievements

本研究が着目したC/N制御による病害抵抗性の駆動という概念が確立されれば、植物-微生物間相互作用に関する研究を行う上で、植物のC/Nを常に適切にコントロールすることが、実験の再現性を得るうえで重要であることを知らしめることになる。また、本研究を発展させることによって、病原体感染時における抵抗性の駆動のためのC/N調整能力を高める手法が確立されれば、食糧生産性の向上などへの貢献が期待できる。

Report

(5 results)
  • 2021 Annual Research Report   Final Research Report ( PDF )
  • 2020 Research-status Report
  • 2019 Research-status Report
  • 2018 Research-status Report
  • Research Products

    (14 results)

All 2022 2021 2020 2019 2018 Other

All Journal Article (4 results) (of which Int'l Joint Research: 2 results,  Peer Reviewed: 4 results,  Open Access: 4 results) Presentation (9 results) Remarks (1 results)

  • [Journal Article] The TGN/EE SNARE protein SYP61 and the ubiquitin ligase ATL31 cooperatively regulate plant responses to carbon/nitrogen conditions in Arabidopsis2022

    • Author(s)
      Yoko Hasegawa, Thais Huarancca Reyes, Tomohiro Uemura, Anirban Baral, Akari Fujimaki, Yongming Luo, Yoshie Morita, Yasushi Saeki, Shugo Maekawa, Shigetaka Yasuda, Koki Mukuta, Yoichiro Fukao, Keiji Tanaka, Akihiko Nakano, Junpei Takagi, Rishikesh P Bhalerao, Junji Yamaguchi, Takeo Sato
    • Journal Title

      THE PLANT CELL

      Volume: 34 Issue: 4 Pages: 1354-1374

    • DOI

      10.1093/plcell/koac014

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Ribosome biogenesis factor OLI2 and its interactor BRX1-2 are associated with morphogenesis and lifespan extension in <i>Arabidopsis thaliana</i>2021

    • Author(s)
      Shugo Maekawa, Shuichi Yanagisawa
    • Journal Title

      Plant Biotechnology

      Volume: 38 Issue: 1 Pages: 117-125

    • DOI

      10.5511/plantbiotechnology.20.1224a

    • NAID

      130008002860

    • ISSN
      1342-4580, 1347-6114
    • Year and Date
      2021-03-25
    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] The bRPS6-Family Protein RFC3 Prevents Interference by the Splicing Factor CFM3b during Plastid rRNA Biogenesis in Arabidopsis thaliana2020

    • Author(s)
      Nagashima Yumi、Ohshiro Katsutomo、Iwase Akiyasu、Nakata Miyuki T.、Maekawa Shugo、Horiguchi Gorou
    • Journal Title

      Plants

      Volume: 9 Issue: 3 Pages: 328-328

    • DOI

      10.3390/plants9030328

    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Overexpression of a Brix Domain-Containing Ribosome Biogenesis Factor ARPF2 and its Interactor ARRS1 Causes Morphological Changes and Lifespan Extension in Arabidopsis thaliana2018

    • Author(s)
      Shugo Maekawa, Yoshiaki Ueda, Shuichi Yanagisawa.
    • Journal Title

      Front. Plant Sci.

      Volume: 9 Pages: 1177-1177

    • DOI

      10.3389/fpls.2018.01177

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] シロイヌナズナIMPDHとリボソームストレスの関係2021

    • Author(s)
      前川修吾、西川幾音、堀口吾朗
    • Organizer
      日本植物学会第85回大会
    • Related Report
      2021 Annual Research Report
  • [Presentation] Destabilization of RPL12B by ubiquitin ligase SZK2-mediated ubiquitination is required for ribosome stress response2021

    • Author(s)
      前川修吾、五十嵐幹太、深田かなえ、高原正裕、塚谷裕一、堀口吾朗
    • Organizer
      第62回日本植物生理学会
    • Related Report
      2020 Research-status Report
  • [Presentation] リボソームストレスシグナル伝達の鍵因子RING型ユビキチンリガーゼSZK2とリボソームタンパク質RPL12Bの関係2020

    • Author(s)
      前川修吾、五十嵐幹太、深田かなえ、高原正裕、塚谷裕一、堀口吾朗
    • Organizer
      日本植物学会第84回大会
    • Related Report
      2020 Research-status Report
  • [Presentation] シロイヌナズナrfc3変異における側根形成異常にはリボソームストレス応答因子SZK1が関与する2020

    • Author(s)
      堀口吾朗、長嶋友美、前川修吾、中田未友希、塚谷裕一
    • Organizer
      日本植物学会第84回大会
    • Related Report
      2020 Research-status Report
  • [Presentation] リボソームストレスシグナル伝達の鍵因子RING型ユビキチンリガーゼSZK2とリボソームタンパク質RPL12Bの役割2020

    • Author(s)
      前川修吾、五十嵐幹太、深田かなえ、高原正裕、西村奎亮、塚谷裕一、堀口吾朗
    • Organizer
      第61回日本植物生理学会
    • Related Report
      2019 Research-status Report
  • [Presentation] リボソーム生合成因子ARPF2とその相互作用因子ARRS1が植物の形態形成に果たす役割の解析2019

    • Author(s)
      前川修吾、植田佳明、柳澤修一
    • Organizer
      第37回日本植物細胞分子生物学会 (京都) 大会
    • Related Report
      2019 Research-status Report
  • [Presentation] 植物リボソームストレスのシグナル伝達因子SZK2とRPL12Bの相互作用の意義2019

    • Author(s)
      前川修吾、五十嵐幹太、深田かなえ、高原正裕、塚谷裕一、堀口吾朗
    • Organizer
      日本植物学会第83回大会
    • Related Report
      2019 Research-status Report
  • [Presentation] リボソームストレスシグナリングにおけるリボソームタンパク質RPL12B及びRING型ユビキチンリガーゼSZK2の機能解析2019

    • Author(s)
      前川修吾、深田かなえ、高原正裕、塚谷裕一、堀口吾朗
    • Organizer
      第60回日本植物生理学会
    • Related Report
      2018 Research-status Report
  • [Presentation] as2 rpl4d二重変異体における葉の背軸化を抑圧するrpl12b及びszk2変異に関する解析2018

    • Author(s)
      前川修吾、深田かなえ、高原正裕、塚谷裕一、堀口吾朗
    • Organizer
      日本植物学会第82回大会
    • Related Report
      2018 Research-status Report
  • [Remarks] 立教大学 理学部 生命理学科 分子植物発生学研究室

    • URL

      https://sites.google.com/rikkyo.ac.jp/rikkyo-horiguchi-lab/home?authuser=0

    • Related Report
      2019 Research-status Report

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Published: 2018-04-23   Modified: 2023-01-30  

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