| Project/Area Number |
18K15616
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| Research Category |
Grant-in-Aid for Early-Career Scientists
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| Allocation Type | Multi-year Fund |
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| Review Section |
Basic Section 52040:Radiological sciences-related
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| Research Institution | Osaka International Cancer Institute |
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Principal Investigator |
Masahiro Morimoto 地方独立行政法人大阪府立病院機構大阪国際がんセンター(研究所), その他部局等, 放射線腫瘍科副部長 (00745359)
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| Project Period (FY) |
2018-04-01 – 2022-03-31
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| Project Status |
Completed (Fiscal Year 2021)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2021: ¥260,000 (Direct Cost: ¥200,000、Indirect Cost: ¥60,000)
Fiscal Year 2020: ¥260,000 (Direct Cost: ¥200,000、Indirect Cost: ¥60,000)
Fiscal Year 2019: ¥260,000 (Direct Cost: ¥200,000、Indirect Cost: ¥60,000)
Fiscal Year 2018: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
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| Keywords | 放射線治療 / 息止め照射 / 限局型小細胞肺癌 |
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| Outline of Final Research Achievements |
Three lung tumor cases are entered in this study. The aim of this study is a comparison of inspiratory breath holding system signal and real-time position management system signal at the radiation planning computed tomography. The three cases of the inspiratory breath holding system signal and real-time position management system signal ±standard deviation(%) are ±4, ±3, ±1 and ±13, ±6, ±7, respectively. The three cases planning target volume of the virtual radiation planning at inspiratory breath holding system are 1.5 cc lower than those of the actual radiation planning of real-time position management system. Then, lung V20 and V5 are 1.2% and 2.7% lower in virtual radiation planning at inspiratory breath holding system than those of actual radiation planning of real-time position management system. The signal of inspiratory breath holding system is more stable than that of real-time position management system.
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| Academic Significance and Societal Importance of the Research Achievements |
学術的意義は、肺腫瘍の放射線治療に関して、吸気実測息止めシステムの信号波形が、従来の腹壁に置いた赤外線マーカーの信号波形に比べて安定していて、治療計画CTに使用可能である。照射体積を減らし、正常組織に当たる放射線の量を減らせる。社会的意義は、臨床応用ができれば、患者の放射線治療による有害事象を減らすことができる。照射体積を減らすことによって、腫瘍内を、今までより正確に線量増加できる可能性がでてくる。
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