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Total gastroenteroscopy using the self-propelling capsule endoscope (SPCE)

Research Project

Project/Area Number 18K15829
Research Category

Grant-in-Aid for Early-Career Scientists

Allocation TypeMulti-year Fund
Review Section Basic Section 53010:Gastroenterology-related
Research InstitutionOsaka Medical and Pharmaceutical University

Principal Investigator

Ota Kazuhiro  大阪医科薬科大学, 医学部, 講師 (50802526)

Project Period (FY) 2018-04-01 – 2023-03-31
Project Status Completed (Fiscal Year 2022)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2019: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2018: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Keywordsカプセル内視鏡検査 / 自走式カプセル内視鏡 / カプセル内視鏡
Outline of Final Research Achievements

The usefulness and safety of a self-propelled capsule endoscope in observing the entire gastrointestinal tract were investigated.
No adverse effects of magnetic fields were observed in the five subjects. When observation of the stomach took longer than expected, the view was found to be narrowed by swallowed saliva. The pylorus was very difficult to move, and the endoscope fins sometimes got caught in the folds of the small and large intestine.
To solve the problems with existing self-propelled capsule endoscopes, it may be necessary to control the environment inside the digestive tract with drugs or other means. The results of this study may serve as a guide for other researchers to develop a capsule endoscope that can be controlled from outside the body and allow real-time observation.

Academic Significance and Societal Importance of the Research Achievements

既存の自走式カプセル内視鏡の問題点を解決するためには、薬などで消化管内の環境をコントロールすることが必要になるかもしれない。今回の成果は、他の研究者が体外から制御可能なカプセル内視鏡を開発し、リアルタイムで観察できるようにするための指針となると思われる。

Report

(6 results)
  • 2022 Annual Research Report   Final Research Report ( PDF )
  • 2021 Research-status Report
  • 2020 Research-status Report
  • 2019 Research-status Report
  • 2018 Research-status Report
  • Research Products

    (2 results)

All 2021 2019

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results) Presentation (1 results)

  • [Journal Article] Safety, efficacy, and maneuverability of a self-propelled capsule endoscope for observation of the human gastrointestinal tract2021

    • Author(s)
      Ota Kazuhiro、Kojima Yuichi、Kakimoto Kazuki、Nouda Sadaharu、Takeuchi Toshihisa、Shindo Yasunori、Ohtsuka Yoshitake、Ohtsuka Naotake、Higuchi Kazuhide
    • Journal Title

      Endoscopy International Open

      Volume: 09 Issue: 09 Pages: E1391-E1396

    • DOI

      10.1055/a-1507-4540

    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] 自走式カプセル内視鏡の開発 単一カプセル内視鏡での全消化管観察と経肛門的逆行性自走による大腸観察への挑戦2019

    • Author(s)
      太田和寛
    • Organizer
      日本消化管学会学術集会
    • Related Report
      2018 Research-status Report

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Published: 2018-04-23   Modified: 2024-01-30  

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