| Project/Area Number |
18K16506
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| Research Category |
Grant-in-Aid for Early-Career Scientists
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| Allocation Type | Multi-year Fund |
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| Review Section |
Basic Section 55060:Emergency medicine-related
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| Research Institution | Yamagata University |
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Principal Investigator |
Onodera Yu 山形大学, 医学部, 助教 (30594329)
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| Project Period (FY) |
2018-04-01 – 2022-03-31
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| Project Status |
Completed (Fiscal Year 2021)
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| Budget Amount *help |
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2020: ¥260,000 (Direct Cost: ¥200,000、Indirect Cost: ¥60,000)
Fiscal Year 2019: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2018: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | ARDS / EIT / Dynamic CT / Regional Compliance / Reginonal Ventilation / Computed Tomography（CT） / impedance tomography / CT / Lung injury |
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| Outline of Final Research Achievements |
This project was to investigate the relation between ventilation and anatomical change of ARDS lung. We used Electrical Impedance Tomography (EIT) to evaluate ventilation and dynamic CT to evaluate anatomical change during ventilation. Due to COVID-19 pandemic, we were only able to enroll few patients. Form these data from few patients, we noticed that regularly applied mechanical ventilation had small change in CT (CT value and movement). This data will be useful for planning future experiment to have specific ventilation mode to have enough signal to be detected and to be evaluated by dynamic CT.
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| Academic Significance and Societal Importance of the Research Achievements |
新たなモニタリング機器を用いる事で障害を受けた肺が人工呼吸される際どのように換気されているか及びどのような解剖学的変化が生じているのか評価し、より障害の少ない呼吸管理法の検討を行う予定だったがCOVID-19のパンデミックの影響で数例のみしかデータを集めることができなかった。しかし得られた数例の所見から将来的に研究を進めるにあたって土台となるデータを得ることができた。
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