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Longitudinal study on perinatal anxiety and depressive symptoms using in-vivo hormones as indicators

Research Project

Project/Area Number 18K17562
Research Category

Grant-in-Aid for Early-Career Scientists

Allocation TypeMulti-year Fund
Review Section Basic Section 58070:Lifelong developmental nursing-related
Research InstitutionFukui Prefectural University

Principal Investigator

Kanekasu Hitomi  福井県立大学, 看護福祉学部, 准教授 (10723645)

Project Period (FY) 2018-04-01 – 2024-03-31
Project Status Completed (Fiscal Year 2023)
Budget Amount *help
¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2020: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2019: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2018: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords周産期 / 抑うつ症状 / 不安 / ボンディング障害 / コルチゾール / オキシトシン / 抑うつ
Outline of Final Research Achievements

The aim of present research is to investigate the relationship between anxiety and depressive symptoms during pregnancy, abnormalities during childbirth, and postpartum depressive symptoms including cortisol and oxytocin as indicators. And our research consists of four studies.
In Study 1, birth weight was associated with depressive symptoms in the second trimester, but not with depressive symptoms in the second trimester. In Study 2, anxiety and depressive symptoms during the second trimester and oxytocin were associated with immediate postpartum maternal-infant bonding. In Study 3, although weight gain during pregnancy and childbirth satisfaction were associated with postpartum depressive symptoms, depressive symptoms during pregnancy were not. In Study 4, depressive symptoms during pregnancy were associated with weight gain during pregnancy. Postpartum depressive symptoms were associated with weight gain during pregnancy, preterm infants, and postnatal social support.

Academic Significance and Societal Importance of the Research Achievements

本研究では、抑うつ症状や不安について自記式質問紙だけではなく、オキシトシンやコルチゾールを指標として用い調査をおこなった。本研究における成果は、産後の抑うつ症状やボンディング障害を予防するためのスクリーニング体制を確立するための一助になると考える。

Report

(7 results)
  • 2023 Annual Research Report   Final Research Report ( PDF )
  • 2022 Research-status Report
  • 2021 Research-status Report
  • 2020 Research-status Report
  • 2019 Research-status Report
  • 2018 Research-status Report
  • Research Products

    (7 results)

All 2024 2023 2022 2021 2020

All Journal Article (2 results) (of which Peer Reviewed: 2 results,  Open Access: 2 results) Presentation (5 results) (of which Int'l Joint Research: 3 results)

  • [Journal Article] Primiparas’ prenatal depressive symptoms, anxiety, and salivary oxytocin level predict early postnatal maternal-infant bonding: a Japanese longitudinal study2024

    • Author(s)
      Kanekasu Hitomi、Shiraiwa Yachiyo、Taira Shu、Watanabe Hiroko
    • Journal Title

      Archives of Women's Mental Health

      Volume: 1 Issue: 4 Pages: 1-1

    • DOI

      10.1007/s00737-024-01441-5

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The Impact of Maternal Prenatal Depressive Symptoms and Anxiety on Infant Birth Weight in Japanese Primiparous Women2021

    • Author(s)
      H Kanekasu, M Nishioka, S Taira, H Watanabe
    • Journal Title

      Women, Women, Midwives and Midwifery journal

      Volume: 1 Issue: 2 Pages: 1-15

    • DOI

      10.36749/wmm.1.2.1-15.2021

    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] Risk factors of prenatal and postpartum depressive symptoms: A longitudinal study among Japanese primiparas2024

    • Author(s)
      Hitomi Kanekasu, Hiroko Watanabe
    • Organizer
      27th East Asian Forum of Nursing Scholars conferenc
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Risk factors of postpartum depressive symptoms among Japanese primiparous women: A longitudinal study.2023

    • Author(s)
      Hitomi Kanekasu, Hiroko Watanabe
    • Organizer
      33rd International Confederation of Midwives Triennial Congress
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 妊娠中期の抑うつ症状・不安・オキシトシンと産後のボンディングとの関連2022

    • Author(s)
      金粕 仁美,白岩八千代,渡邊 浩子
    • Organizer
      第36回日本助産学会学術集会
    • Related Report
      2021 Research-status Report
  • [Presentation] Impact of Maternal Prenatal Depressive Symptoms and Anxiety on Infant Birth Weight in Japanese Primiparous Women2021

    • Author(s)
      Hitomi Kanekasu, Mayumi Nishioka, Hiroko Watanabe
    • Organizer
      24th East Asian of Nursing Scholars
    • Related Report
      2020 Research-status Report
    • Int'l Joint Research
  • [Presentation] 妊娠期の母親の不安・抑うつ症状と子どもの在胎週数・出生体重との関連2020

    • Author(s)
      金粕仁美,岡野尚子,渡邊浩子
    • Organizer
      第34回日本助産学会学術集会
    • Related Report
      2019 Research-status Report

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Published: 2018-04-23   Modified: 2025-01-30  

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