Prospective study on the association of active commuting and diabetes incidence

• Project/Area Number: 18K17925
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 59040:Nutrition science and health science-related
• Research Institution: Kyushu University
• Principal Investigator: HONDA Takanori 九州大学, 医学研究院, 助教 (30773353)
• Project Period (FY): 2018-04-01 – 2022-03-31
• Project Status: Completed (Fiscal Year 2021)
• Budget Amount: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000); Fiscal Year 2021: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2020: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2019: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2018: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
• Keywords: 身体活動 / 運動 / 前向きコホート / 糖尿病 / 糖代謝異常 / 疫学 / 予防医学 / 通勤 / 行動 / 前向きコホート研究

Outline of Final Research Achievements

The purpose of this study was to examine the influence of active commuting on the incidence of diabetes using the data from a cohort study of community residents. A total of 1,208 residents without diabetes who aged 40-79 years and underwent a medical checkup in 1988 in the town of Hisayama were followed-up for 14 years. The results showed that the risk of developing diabetes was significantly lower among active commuters than among non-active commuters. The applicability of this finding in the post-COVID era was examined through a web survey. Results showed that active commuters accounted for more than half of all commuters, and longer duration of non-active commuting was associated with a higher odds ratio for having obesity. These results suggest that active commuting may be effective in preventing metabolic diseases in Japan after the COVID-19 pandemic.

Academic Significance and Societal Importance of the Research Achievements

我が国の糖尿病有病率は高止まりしている。一次予防が課題であり、余暇運動によるポピュレーションアプローチが期待されるが、特に中年期においては主に多忙のため運動習慣者の割合は増えていない。そこで、中年期の身体活動量を増加させる代替施策として、活発な通勤の普及が進められている。現在改定中の身体活動ガイドラインにおいても、自転車通勤を推奨事項として取り入れる予定となっている。本研究の知見は、我が国で活発な通勤、特に自転車通勤が有効である可能性が示し、上記ガイドラインの推奨を裏付けするものである。

Research Products

• [Journal Article] Development and Validation of a Risk Prediction Model for Atherosclerotic Cardiovascular Disease in Japanese Adults: The Hisayama Study (2022)
  • Author(s): Honda, Takanori; Chen, Sanmei; Hata, Jun; Yoshida, Daigo; Hirakawa, Yoichiro; Furuta, Yoshihiko; Shibata, Mao; Sakata, Satoko; Kitazono, Takanari; Ninomiya, Toshiharu;
  • Journal Title: Journal of Atherosclerosis and Thrombosis Volume: 29 Issue: 3 Pages: 345-361
  • DOI: 10.5551/jat.61960
  • NAID: 130008165681
  • ISSN: 1340-3478, 1880-3873
  • Year and Date: 2022-03-01
  • Peer Reviewed / Open Access
• [Journal Article] Changes in Body Weight and Concurrent Changes in Cardiovascular Risk Profiles in Community Residents in Japan: the Hisayama Study (2022)
  • Author(s): Honda, Takanori; Ishida, Yuki; Oda, Masaaki; Noguchi, Kenichi; Chen, Sanmei; Sakata, Satoko; Oishi, Emi; Furuta, Yoshihiko; Yoshida, Daigo; Hirakawa, Yoichiro;
  • Journal Title: Journal of Atherosclerosis and Thrombosis Volume: 29 Issue: 2 Pages: 252-267
  • DOI: 10.5551/jat.59394
  • NAID: 130008149940
  • ISSN: 1340-3478, 1880-3873
  • Year and Date: 2022-02-01
  • Peer Reviewed / Open Access
• [Journal Article] Associations of Objectively-Measured Sedentary Time and Patterns with Cognitive Function in Non-Demented Japanese Older Adults: A Cross-Sectional Study (2022)
  • Author(s): Chen, Sanmei; Chen, Tao; Honda, Takanori; Nofuji, Yu; Kishimoto, Hiro; Narazaki, Kenji;
  • Journal Title: International journal of environmental research and public health Volume: 19 Issue: 4 Pages: 1999-1999
  • DOI: 10.3390/ijerph19041999
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Muscle-strengthening activities are associated with lower risk and mortality in major non-communicable diseases: a systematic review and meta-analysis of cohort studies (2022)
  • Author(s): Momma, Haruki; Kawakami, Ryoko; Honda, Takanori; Sawada, Susumu S;
  • Journal Title: British Journal of Sports Medicine Volume: - Issue: 13 Pages: 755-763
  • DOI: 10.1136/bjsports-2021-105061
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Association between chronic low back pain and regional brain atrophy in a Japanese older population: the Hisayama Study (2022)
  • Author(s): Asada Masako、Shibata Mao、Hirabayashi Naoki、Ohara Tomoyuki、Furuta Yoshihiko、Nakazawa Taro、Honda Takanori、Hata Jun、Hosoi Masako、Sudo Nobuyuki、Yamaura Ken、Ninomiya Toshiharu
  • Journal Title: Pain Volume: Publish Ahead of Print Issue: 11 Pages: 2185-2193
  • DOI: 10.1097/j.pain.0000000000002612
  • Peer Reviewed / Open Access
• [Journal Article] Long-term association of vegetable and fruit intake with risk of dementia in Japanese older adults: the Hisayama study (2022)
  • Author(s): Kimura, Yasumi; Yoshida, Daigo; Ohara, Tomoyuki; Hata, Jun; Honda, Takanori; Hirakawa, Yoichiro; Shibata, Mao; Oishi, Emi; Sakata, Satoko; Furuta, Yoshihiko;
  • Journal Title: BMC geriatrics Volume: 22 Issue: 1 Pages: 44574-44574
  • DOI: 10.1186/s12877-022-02939-2
  • Peer Reviewed / Open Access
• [Journal Article] Risk Prediction Model for Incident Atrial Fibrillation in a General Japanese Population ― The Hisayama Study ― (2021)
  • Author(s): Hata Jun、Nagata Takuya、Sakata Satoko、Oishi Emi、Furuta Yoshihiko、Hirakawa Yoichiro、Honda Takanori、Yoshida Daigo、Kitazono Takanari、Ninomiya Toshiharu
  • Journal Title: Circulation Journal Volume: 85 Issue: 8 Pages: 1373-1382
  • DOI: 10.1253/circj.CJ-20-0794
  • NAID: 130008066724
  • ISSN: 1346-9843, 1347-4820
  • Year and Date: 2021-07-21
  • Peer Reviewed / Open Access
• [Journal Article] Dietary fiber intake and risk of type 2 diabetes in a general Japanese population: The Hisayama Study (2021)
  • Author(s): Kimura, Yasumi; Yoshida, Daigo; Hirakawa, Yoichiro; Hata, Jun; Honda, Takanori; Shibata, Mao; Sakata, Satoko; Uchida, Kazuhiro; Kitazono, Takanari; Ninomiya, Toshiharu;
  • Journal Title: Journal of diabetes investigation Volume: 12 Issue: 4 Pages: 527-536
  • DOI: 10.1111/jdi.13377
  • Peer Reviewed / Open Access
• [Journal Article] N-Terminal Pro B-Type Natriuretic Peptide and Incident CKD (2021)
  • Author(s): Sasaki, Takaya; Oishi, Emi; Nagata, Takuya; Sakata, Satoko; Chen, Sanmei; Furuta, Yoshihiko; Honda, Takanori; Yoshida, Daigo; Hata, Jun; Tsuboi, Nobuo;
  • Journal Title: Kidney International Reports Volume: 6 Issue: 4 Pages: 976-985
  • DOI: 10.1016/j.ekir.2021.01.006
  • Peer Reviewed / Open Access
• [Journal Article] High serum folate concentrations are associated with decreased risk of mortality among Japanese adults (2021)
  • Author(s): Sanmei Chen, Takanori Honda, Jun Hata, Satoko Sakata, Yoshihiko Furuta, Daigo Yoshida, Mao Shibata, Tomoyuki Ohara, Yoichiro Hirakawa, Emi Oishi, Takanari Kitazono, Toshiharu Ninomiya
  • Journal Title: The Journal of Nutrition Volume: 151 Issue: 3 Pages: 657-665
  • DOI: 10.1093/jn/nxaa382
  • Peer Reviewed / Open Access
• [Journal Article] Current status of the certification of long-term care insurance among individuals with dementia in a Japanese community: The Hisayama Study (2021)
  • Author(s): Ohara, Tomoyuki; Yoshida, Daigo; Hata, Jun; Shibata, Mao; Honda, Takanori; Furuta, Yoshihiko; Hirabayashi, Naoki; Kitazono, Takanari; Nakao, Tomohiro; Ninomiya, Toshiharu;
  • Journal Title: Psychiatry and clinical neurosciences Volume: - Issue: 5 Pages: 182-182
  • DOI: 10.1111/pcn.13204
  • Peer Reviewed / Open Access
• [Journal Article] Midlife and late-life diabetes and sarcopenia in a general older Japanese population: the Hisayama Study (2021)
  • Author(s): Kimitaka Nakamura, Daigo Yoshida, Takanori Honda, Jun Hata, Mao Shibata, Yoichiro Hirakawa, Yoshihiko Furuta, Hiro Kishimoto, Tomoyuki Ohara, Sanmei Chen, Takanari Kitazono, Yasuharu Nakashima, Toshiharu Ninomiya
  • Journal Title: J Diabetes Investig Volume: in press Issue: 10 Pages: 1-26
  • DOI: 10.1111/jdi.13550
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Urinary N-terminal pro?B-type natriuretic peptide as a biomarker for cardiovascular events in a general Japanese population: the Hisayama Study (2021)
  • Author(s): Yamasaki, Keisuke; Hata, Jun; Ide, Tomomi; Nagata, Takuya; Sakata, Satoko; Yoshida, Daigo; Honda, Takanori; Hirakawa, Yoichiro; Nakano, Toshiaki; Kitazono, Takanari;
  • Journal Title: Environmental health and preventive medicine Volume: 26 Issue: 1 Pages: 44571-44571
  • DOI: 10.1186/s12199-021-00970-0
  • NAID: 210000158976
  • Peer Reviewed / Open Access
• [Journal Article] Comparison of the contributions of impaired beta cell function and insulin resistance to the development of type 2 diabetes in a Japanese community: the Hisayama Study (2021)
  • Author(s): Yoshinari, Masahito; Hirakawa, Yoichiro; Hata, Jun; Higashioka, Mayu; Honda, Takanori; Yoshida, Daigo; Mukai, Naoko; Nakamura, Udai; Kitazono, Takanari; Ninomiya, Toshiharu;
  • Journal Title: Diabetologia Volume: 64 Issue: 8 Pages: 1775-1784
  • DOI: 10.1007/s00125-021-05459-7
  • Peer Reviewed
• [Journal Article] Development of a risk prediction model for incident hypertension in Japanese individuals: the Hisayama Study (2021)
  • Author(s): Oishi, Emi; Hata, Jun; Honda, Takanori; Sakata, Satoko; Chen, Sanmei; Hirakawa, Yoichiro; Yoshida, Daigo; Shibata, Mao; Ohara, Tomoyuki; Furuta, Yoshihiko;
  • Journal Title: Hypertension Research Volume: 44 Issue: 9 Pages: 1221-1229
  • DOI: 10.1038/s41440-021-00673-7
  • Peer Reviewed
• [Journal Article] Development of a dementia prediction model for primary care: The Hisayama Study (2021)
  • Author(s): Honda, Takanori; Ohara, Tomoyuki; Yoshida, Daigo; Shibata, Mao; Ishida, Yuki; Furuta, Yoshihiko; Oishi, Emi; Hirakawa, Yoichiro; Sakata, Satoko; Hata, Jun;
  • Journal Title: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring Volume: 13 Issue: 1
  • DOI: 10.1002/dad2.12221
  • Peer Reviewed / Open Access
• [Journal Article] Potential utility of physical function measures to improve the risk prediction of functional disability in community-dwelling older Japanese adults: a prospective study (2021)
  • Author(s): Chen, Tao; Honda, Takanori; Chen, Sanmei; Kishimoto, Hiro; Kumagai, Shuzo; Narazaki, Kenji;
  • Journal Title: BMC geriatrics Volume: 21 Issue: 1 Pages: 44569-44569
  • DOI: 10.1186/s12877-021-02415-3
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Multiple-region grey matter atrophy as a predictor for the development of dementia in a community: the Hisayama Study (2021)
  • Author(s): Nakazawa Taro、Ohara Tomoyuki、Hirabayashi Naoki、Furuta Yoshihiko、Hata Jun、Shibata Mao、Honda Takanori、Kitazono Takanari、Nakao Tomohiro、Ninomiya Toshiharu
  • Journal Title: Journal of Neurology, Neurosurgery & Psychiatry Volume: 93 Issue: 3 Pages: 263-271
  • DOI: 10.1136/jnnp-2021-326611
  • Peer Reviewed / Open Access
• [Journal Article] Association of daily sleep duration with the incident dementia by serum soluble <scp>TREM2</scp> in a community (2021)
  • Author(s): Ohara Tomoyuki、Hata Jun、Tanaka Masashi、Honda Takanori、Yamakage Hajime、Inoue Takayuki、Hirakawa Yoichiro、Kusakabe Toru、Shibata Mao、Kitazono Takanari、Nakao Tomohiro、Satoh‐Asahara Noriko、Ninomiya Toshiharu
  • Journal Title: Journal of the American Geriatrics Society Volume: 70 Issue: 4 Pages: 1147-1156
  • DOI: 10.1111/jgs.17634
  • Peer Reviewed / Open Access
• [Journal Article] Decline in Handgrip Strength From Midlife to Late-Life is Associated With Dementia in a Japanese Community: The Hisayama Study (2020)
  • Author(s): Hatabe Y, Shibata M, Ohara T, Oishi E, Yoshida D, Honda T, Hata J, Kanba S, Kitazono T, Ninomiya T.
  • Journal Title: Journal of Epidemiology Volume: 30 Issue: 1 Pages: 15-23
  • DOI: 10.2188/jea.JE20180137
  • NAID: 130007782493
  • ISSN: 0917-5040, 1349-9092
  • Year and Date: 2020-01-05
  • Peer Reviewed / Open Access
• [Journal Article] Serum N-terminal pro-B-type natriuretic peptide as a predictor for future development of atrial fibrillation in a general population: the Hisayama Study (2020)
  • Author(s): Nagata Takuya、Hata Jun、Sakata Satoko、Oishi Emi、Honda Takanori、Furuta Yoshihiko、Ohara Tomoyuki、Yoshida Daigo、Hirakawa Yoichiro、Shibata Mao、Ide Tomomi、Kitazono Takanari、Tsutsui Hiroyuki、Ninomiya Toshiharu
  • Journal Title: International Journal of Cardiology Volume: 320 Pages: 90-96
  • DOI: 10.1016/j.ijcard.2020.06.018
  • Peer Reviewed
• [Journal Article] Lifetime cumulative incidence of dementia in a community-dwelling elderly population in Japan (2020)
  • Author(s): Yoshida, Daigo; Ohara, Tomoyuki; Hata, Jun; Shibata, Mao; Hirakawa, Yoichiro; Honda, Takanori; Furuta, Yoshihiko; Oishi, Emi; Sakata, Satoko; Kanba, Shigenobu;
  • Journal Title: Neurology Volume: 95 Issue: 5
  • DOI: 10.1212/wnl.0000000000009917
  • Peer Reviewed / Open Access
• [Journal Article] 30-minute postload plasma glucose levels during an oral glucose tolerance test predict the risk of future type 2 diabetes: the Hisayama Study (2020)
  • Author(s): Hirakawa, Yoichiro; Hata, Jun; Yoshinari, Masahito; Higashioka, Mayu; Yoshida, Daigo; Shibata, Mao; Honda, Takanori; Sakata, Satoko; Kato, Hiroyuki; Teramoto, Takanori;
  • Journal Title: BMJ Open Diabetes Research and Care Volume: 8 Issue: 1 Pages: e001156-e001156
  • DOI: 10.1136/bmjdrc-2019-001156
  • Peer Reviewed / Open Access
• [Journal Article] Association between serum glycated albumin and risk of cardiovascular disease in a Japanese community: The Hisayama Study (2020)
  • Author(s): Mihara, Akane; Ohara, Tomoyuki; Hata, Jun; Honda, Takanori; Chen, Sanmei; Sakata, Satoko; Oishi, Emi; Hirakawa, Yoichiro; Nakao, Tomohiro; Kitazono, Takanari;
  • Journal Title: Atherosclerosis Volume: 311 Pages: 52-59
  • DOI: 10.1016/j.atherosclerosis.2020.08.016
  • Peer Reviewed
• [Journal Article] Influence of the accumulation of unhealthy eating habits on obesity in a general Japanese population: the Hisayama Study. (2020)
  • Author(s): Ishida Y, Yoshida D, Honda T, Hirakawa Y, Shibata M, Sakata S, Furuta Y, Oishi E, Hata J, Kitazozno T, Ninomiya T
  • Journal Title: Nutrients Volume: 12 Issue: 10 Pages: 3160-3160
  • DOI: 10.3390/nu12103160
  • Peer Reviewed / Open Access
• [Journal Article] Serum uric acid levels and cardiovascular mortality in a general Japanese population: the Hisayama Study (2020)
  • Author(s): Sakata Satoko、Hata Jun、Honda Takanori、Hirakawa Yoichiro、Oishi Emi、Shibata Mao、Yoshida Daigo、Goto Kenichi、Kitazono Takanari、Ninomiya Toshiharu
  • Journal Title: Hypertension Research Volume: - Issue: 6 Pages: 560-568
  • DOI: 10.1038/s41440-019-0390-8
  • Peer Reviewed
• [Journal Article] Elevated serum glycated albumin and glycated albumin to hemoglobin A1c ratio were associated with hippocampal atrophy in a general elderly population of Japanese: the Hisayama Study. (2020)
  • Author(s): Ohara Tomoyuki、Furuta Yoshihiko、Hirabayashi Naoki、Hata Jun、Hirakawa Yoichiro、Honda Takanori、Yoshida Daigo、Shibata Mao、Kitazono Takanari、Ninomiya Toshiharu
  • Journal Title: Journal of Diabetes Investigation Volume: - Issue: 4 Pages: 971-979
  • DOI: 10.1111/jdi.13220
  • Peer Reviewed / Open Access
• [Journal Article] Dose-Response Association Between Accelerometer-Assessed Physical Activity and Incidence of Functional Disability in Older Japanese Adults: A 6-Year Prospective Study (2020)
  • Author(s): Chen Tao、Honda Takanori、Chen Sanmei、Narazaki Kenji、Kumagai Shuzo
  • Journal Title: The Journals of Gerontology: Series A Volume: - Issue: 9 Pages: 129-136
  • DOI: 10.1093/gerona/glaa046
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Dairy consumption and risk of functional disability in an elderly Japanese population: the Hisayama Study (2019)
  • Author(s): Yoshida Daigo、Ohara Tomoyuki、Hata Jun、Shibata Mao、Hirakawa Yoichiro、Honda Takanori、Uchida Kazuhiro、Takasugi Satoshi、Kitazono Takanari、Kiyohara Yutaka、Ninomiya Toshiharu
  • Journal Title: The American Journal of Clinical Nutrition Volume: 109 Issue: 6 Pages: 1664-1671
  • DOI: 10.1093/ajcn/nqz040
  • Peer Reviewed
• [Journal Article] Association Between Serum β-Alanine and Risk of Dementia (2019)
  • Author(s): Hata Jun、Ohara Tomoyuki、Katakura Yoshinori、Shimizu Kuniyoshi、Yamashita Shuntaro、Yoshida Daigo、Honda Takanori、Hirakawa Yoichiro、Shibata Mao、Sakata Satoko、Kitazono Takanari、Kuhara Satoru、Ninomiya Toshiharu
  • Journal Title: American Journal of Epidemiology Volume: 188 Issue: 9 Pages: 1637-1645
  • DOI: 10.1093/aje/kwz116
  • Peer Reviewed
• [Journal Article] Serum Ethylamine Levels as an Indicator of l-Theanine Consumption and the Risk of Type 2 Diabetes in a General Japanese Population: The Hisayama Study (2019)
  • Author(s): Ninomiya Toshiharu、Kanzaki Noriyuki、Hirakawa Yoichiro、Yoshinari Masahito、Higashioka Mayu、Honda Takanori、Shibata Mao、Sakata Satoko、Yoshida Daigo、Teramoto Takanori、Takemoto Susumu、Nishimoto Shozo、Hata Jun、Kitazono Takanari
  • Journal Title: Diabetes Care Volume: 42 Issue: 7 Pages: 1234-1240
  • DOI: 10.2337/dc18-2655
  • Peer Reviewed
• [Journal Article] NT‐proBNP and Risk of Dementia in a General Japanese Elderly Population: The Hisayama Study (2019)
  • Author(s): Nagata Takuya、Ohara Tomoyuki、Hata Jun、Sakata Satoko、Furuta Yoshihiko、Yoshida Daigo、Honda Takanori、Hirakawa Yoichiro、Ide Tomomi、Kanba Shigenobu、Kitazono Takanari、Tsutsui Hiroyuki、Ninomiya Toshiharu
  • Journal Title: Journal of the American Heart Association Volume: 8 Issue: 17
  • DOI: 10.1161/jaha.118.011652
  • Peer Reviewed / Open Access
• [Journal Article] Ratios of serum eicosapentaenoic acid to arachidonic acid and docosahexaenoic acid to arachidonic acid were inversely associated with serum resistin levels: The Hisayama Study (2019)
  • Author(s): Higashioka Mayu、Hirakawa Yoichiro、Kawamura Ryoichi、Honda Takanori、Hata Jun、Yoshida Daigo、Takata Yasunori、Kitazono Takanari、Osawa Haruhiko、Ninomiya Toshiharu
  • Journal Title: Journal of Diabetes Investigation Volume: 11 Issue: 2 Pages: 482-489
  • DOI: 10.1111/jdi.13129
  • Peer Reviewed / Open Access
• [Journal Article] Serum Lipopolysaccharide‐Binding Protein Levels and the Incidence of Cardiovascular Disease in a General Japanese Population: The Hisayama Study (2019)
  • Author(s): Asada Masako、Oishi Emi、Sakata Satoko、Hata Jun、Yoshida Daigo、Honda Takanori、Furuta Yoshihiko、Shibata Mao、Suzuki Kosuke、Watanabe Hiroshi、Murayama Norihito、Kitazono Takanari、Yamaura Ken、Ninomiya Toshiharu
  • Journal Title: Journal of the American Heart Association Volume: 8 Issue: 21
  • DOI: 10.1161/jaha.119.013628
  • Peer Reviewed / Open Access
• [Journal Article] Objectively measured sedentary time and diabetes mellitus in a general Japanese population: the Hisayama Study (2019)
  • Author(s): Takanori Honda, Hiro Kishimoto, Naoko Mukai, Jun Hata, Daigo Yoshida, Yoichiro Hirakawa, Mao Shibata, Tomoyuki Ohara, Shuzo Kumagai, Toshiharu Ninomiya
  • Journal Title: J Diab Invest Volume: 10 Issue: 3 Pages: 809-816
  • DOI: 10.1111/jdi.12968
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Longitudinal Changes of Physical Activity and Sedentary Time in the Middle-Aged and Older Japanese Population: The Hisayama Study (2019)
  • Author(s): Yonemoto Koji、Honda Takanori、Kishimoto Hiro、Yoshida Daigo、Hata Jun、Mukai Naoko、Shibata Mao、Hirakawa Yoichiro、Ninomiya Toshiharu、Kumagai Shuzo
  • Journal Title: Journal of Physical Activity and Health Volume: 16 Issue: 2 Pages: 165-171
  • DOI: 10.1123/jpah.2017-0701
  • Peer Reviewed
• [Journal Article] Patterns and Levels of Sedentary Behavior and Physical Activity in a General Japanese Population: The Hisayama Study (2018)
  • Author(s): Tao Chen, Hiro Kishimoto, Takanori Honda, Jun Hata, Daigo Yoshida, Naoko Mukai, Mao Shibata, Toshiharu Ninomiya, Shuzo Kumagai
  • Journal Title: Journal of Epidemiology Volume: 28 Issue: 5 Pages: 260-265
  • DOI: 10.2188/jea.JE20170012
  • NAID: 130006732098
  • ISSN: 0917-5040, 1349-9092
  • Year and Date: 2018-05-05
  • Peer Reviewed / Open Access
• [Journal Article] Association of daily sleep duration with the risk of dementia and mortality in a Japanese community (2018)
  • Author(s): Tomoyuki Ohara, Takanori Honda, Jun Hata, Daigo Yoshida, Naoko Mukai, Yoichiro Hirakawa, Mao Shibata, Hiro Kishimoto, Takanari Kitazono, Shigenobu Kanba, Toshiharu Ninomiya
  • Journal Title: Journal of the American Geriatrics Society Volume: in press Issue: 10 Pages: 1911-1918
  • DOI: 10.1111/jgs.15446
  • Peer Reviewed / Open Access
• [Journal Article] A potential novel pathological implication of serum soluble triggering receptor expressed on myeloid cell 2 in insulin resistance in a general Japanese population: The Hisayama study (2018)
  • Author(s): Tanaka Masashi、Honda Takanori、Yamakage Hajime、Hata Jun、Yoshida Daigo、Hirakawa Yoichiro、Shibata Mao、Inoue Takayuki、Kusakabe Toru、Satoh-Asahara Noriko、Ninomiya Toshiharu
  • Journal Title: Diabetes Research and Clinical Practice Volume: 146 Pages: 225-232
  • DOI: 10.1016/j.diabres.2018.10.007
  • Peer Reviewed
• [Journal Article] Development and validation of modified risk prediction models for cardiovascular disease and its subtypes: The Hisayama Study (2018)
  • Author(s): Honda Takanori、Yoshida Daigo、Hata Jun、Hirakawa Yoichiro、Ishida Yuki、Shibata Mao、Sakata Satoko、Kitazono Takanari、Ninomiya Toshiharu
  • Journal Title: Atherosclerosis Volume: 279 Pages: 38-44
  • DOI: 10.1016/j.atherosclerosis.2018.10.014
  • Peer Reviewed
• [Journal Article] Serum Soluble Triggering Receptor Expressed on Myeloid Cells 2 as a Biomarker for Incident Dementia: The Hisayama Study (2018)
  • Author(s): Ohara Tomoyuki、Hata Jun、Tanaka Masashi、Honda Takanori、Yamakage Hajime、Yoshida Daigo、Inoue Takayuki、Hirakawa Yoichiro、Kusakabe Toru、Shibata Mao、Teraoka Tadashi、Kitazono Takanari、Kanba Shigenobu、Satoh-Asahara Noriko、Ninomiya Toshiharu
  • Journal Title: Annals of Neurology Volume: 85 Issue: 1 Pages: 47-58
  • DOI: 10.1002/ana.25385
  • Peer Reviewed / Open Access
• [Presentation] 活動的な通勤および通勤形態と糖尿病発症リスクの関連：久山町研究 第32回日本疫学会学術総会 (2022)
  • Author(s): 本田貴紀、平川洋一郎、秦 淳、陳三妹、柴田舞欧、坂田智子、古田芳彦、東岡真由、大石絵美、北園孝成、二宮利治
  • Organizer: 第32回日本疫学会学術総会
• [Presentation] Association between gait speed and cognitive impairment among community-dwelling older population: the Japan Prospective Studies Collaboration for Aging and Dementia (JPSC-AD). (2022)
  • Author(s): Suzuki K, Niimura H, Shikimoto R, Kida H, Miyasaka Y, Shibata M, Honda T, Ohara T, Hata J, Ninimoya T, Mimura M, on behalf of the JPSC-AD Study Group.
  • Organizer: he 15th International Conference on Alzheimer’s and Parkinson’s Diseases and related neurological disorders
  • Int'l Joint Research
• [Presentation] 筋トレと有酸素運動の複合と健康アウトカムの関係：メタ解析の予備的検討 (2021)
  • Author(s): 本田貴紀、川上諒子、門間陽樹、澤田 亨
  • Organizer: 第７6回日本体力医学会大会
• [Presentation] 動脈硬化性心血管疾患発症リスク予測モデルの開発：久山町研究 (2021)
  • Author(s): 本田貴紀、陳三妹、秦 淳、吉田大悟、平川洋一郎、古田芳彦、柴田舞欧、坂田智子、北園孝成、二宮利治
  • Organizer: 第31回日本疫学会学術総会
• [Presentation] Cognitive Frailty And Risk Of Functional Disability In Older Japanese Adults: A 4-Year Prospective Study. (2021)
  • Author(s): Chen S, Honda T, Chen T, Matsuzaki H, Kishimoto H, Kumagai S, Narazaki K.
  • Organizer: Geriatrics Society of America Annual Scientific Meeting
  • Int'l Joint Research
• [Presentation] Dose-response associations between accelerometer measured physical activity and sedentary time and all-cause mortality in community-dwelling older Japanese adults: A 9-year prospective study. (2021)
  • Author(s): Chen T, Chen S, Honda T, Kishimoto H, Nofuji Y, Kumagai S, Narazaki K.
  • Organizer: 3rd international Academic Forum on Sports Medicine and Health
  • Int'l Joint Research
• [Presentation] Association of preserved ratio impaired spirometry with mortality risk: the Hisayama Study. (2021)
  • Author(s): Washio Y, Sakata S, Fukuyama S, Sasaki T, Honda T, Kan-o K, Hata J, Kitazono T, Matsumoto K, Ninomiya T.
  • Organizer: The 25th Congress of the Asian Pacific Society of Respirology
  • Int'l Joint Research
• [Presentation] 地域高齢住民における歩行速度と認知症発症および脳容積との関連：久山町研究 (2021)
  • Author(s): 多治見昂洋, 古田芳彦, 平林直樹, 本田貴紀, 秦淳, 小原知之, 柴田舞欧, 中尾智博, 北園孝成, 中島康晴, 二宮利治
  • Organizer: 第36回日本整形外科学会基礎学術集会
• [Presentation] 筋トレの実施と健康アウトカムの関連：メタ解析の予備的検討 (2021)
  • Author(s): 門間陽樹、川上諒子、本田貴紀、澤田亨
  • Organizer: 第７6回日本体力医学会大会
• [Presentation] 筋トレ実施時間と健康アウトカムの量反応関係：メタ解析の予備的検討 (2021)
  • Author(s): 川上諒子、門間陽樹、本田貴紀、澤田亨
  • Organizer: 第７6回日本体力医学会大会
• [Presentation] 認知度調査と全身持久力以外の体力の基盤及び新たな分野の基準作成レビュー班の取り組み（シンポジウム：身体活動ガイドライン改定の方向性と内容） (2021)
  • Author(s): 澤田 亨、原田和弘、門間陽樹、川上諒子、本田貴紀、松下宗洋、武田典子、黒澤 彩、郡山さくら、Robert A. Sloan
  • Organizer: 第７6回日本体力医学会大会
• [Presentation] 地域高齢住民における大脳白質病変と認知症発症の関係：久山町研究 (2021)
  • Author(s): 中澤太郎、小原知之、平林直樹、古田芳彦、秦 淳、柴田舞欧、本田貴紀、北園孝成、中尾智博、二宮利治
  • Organizer: 第36回日本老年精神医学会
• [Presentation] 地域高齢住民における脳部位別灰白質容積低下と認知症発症の関連：久山町研究 (2021)
  • Author(s): 中澤太郎、小原知之、平林直樹、古田芳彦、秦 淳、柴田舞欧、本田貴紀、北園孝成、中尾智博、二宮利治
  • Organizer: 第117回日本精神神経学会
• [Presentation] 地域一般住民におけるPreserved Ratio Impaired Spirometryと死亡リスクの関連：久山町研究 (2021)
  • Author(s): 鷲尾康圭，坂田智子，福山聡，佐々木峻也，本田貴紀，神尾敬子，秦?淳，北園孝成，松元幸一郎，二宮利治
  • Organizer: 第114回呼吸生理フォーラム/第94回閉塞性肺疾患研究会
• [Presentation] 地域高齢住民における魚介類摂取量と認知症発症の関連：久山町研究 (2021)
  • Author(s): 陳三妹、本田貴紀、小原知之、秦 淳、吉田大悟、平川洋一郎、柴田舞欧、坂田智子、中尾智博、二宮利治
  • Organizer: 第57回日本循環器病予防学会
• [Presentation] 脳卒中初発後の再発率・死亡率の時代的推移：久山町研究 (2021)
  • Author(s): 中西泰之、秦 淳、古田芳彦、吉田大悟、本田貴紀、脇坂義信、吾郷哲朗、北園孝成、二宮利治
  • Organizer: 第46回日本脳卒中学会
• [Presentation] Association of serum folate and vitamin B-12 concentrations with all-cause mortality: the Hisayama Study. (2021)
  • Author(s): Chen S, Honda T, Hata J, Sakata S, Furuta Y, Yoshida D, Shibata M, Ohara T, Hirakawa Y, Oishi E, Kitazono T, Ninomiya T
  • Organizer: 第31回日本疫学会学術総会
• [Presentation] 地域住民における野菜・果物摂取量と認知症発症との関連の検討：久山町研究． (2021)
  • Author(s): 木村安美、吉田大悟、小原知之、秦 淳、本田貴紀、柴田舞欧、坂田智子、平川洋一郎、内田和弘、二宮利治
  • Organizer: 第31回日本疫学会学術総会、Web、2021.1
• [Presentation] 動脈硬化性心血管疾患発症リスク予測モデルの開発：久山町研究． (2021)
  • Author(s): 本田貴紀、陳三妹、秦 淳、吉田大悟、平川洋一郎、古田芳彦、柴田舞欧、坂田智子、北園孝成、二宮利治
  • Organizer: 第31回日本疫学会学術総会、Web、2021.1
• [Presentation] Association[of serum folate and vitamin B-12 concentrations with all-cause mortality: the Hisayama Study. (2021)
  • Author(s): Chen S, Honda T, Hata J, Sakata S, Furuta Y, Yoshida D, Shibata M, Ohara T, Hirakawa Y, Oishi E, Kitazono T, Ninomiya T
  • Organizer: 第31回日本疫学会学術総会、Web、2021.1
• [Presentation] 地域高齢住民における中年期および高齢期の糖尿病罹患とサルコペニア発症の関連 -久山町研究- (Midlife and late-life diabetes and sarcopenia in a general elderly Japanese population: the Hisayama Study) (2020)
  • Author(s): 中村公隆、吉田大悟、本田貴紀、秦 淳、柴田舞欧、平川洋一郎、古田芳彦、岸本裕歩、北園孝成、中島康晴、二宮利治
  • Organizer: 第93回日本整形外科学会学術総会
• [Presentation] 血清Mac-2結合蛋白糖鎖修飾異性体(M2BPGi)と糖尿病発症の関連：久山町研究 (2020)
  • Author(s): 東岡真由、平川洋一郎、吉成匡人、本田貴紀、吉田大悟、秦 淳、大澤春彦、二宮利治
  • Organizer: 第63回日本糖尿病学会年次学術集会
• [Presentation] NT-proBNPと慢性腎臓病発症との関連：久山町研究 (2020)
  • Author(s): 佐々木峻也、大石絵美、坂田智子、本田貴紀、秦淳、坪井伸夫、横尾隆、二宮利治
  • Organizer: 第63回日本腎臓学会学術総会
• [Presentation] 認知症発症リスク予測モデルの開発：久山町研究 (2020)
  • Author(s): 本田貴紀、小原知之、吉田大悟、平川洋一郎、石田有紀、古田芳彦、大石絵美、坂田智子、柴田舞欧、秦 淳、北園孝成、二宮利治
  • Organizer: 第30回日本疫学会学術総会
• [Presentation] Association between serum homocysteine and risk of dementia in Japanese elderly: the Hisayama Study (2020)
  • Author(s): Chen S, Honda T, Ohara T, Hata J, Hirakawa Y, Yoshida D, Shibata M, Kitazono T, Ninomiya T
  • Organizer: 第30回日本疫学会学術総会
• [Presentation] Serum NT-proBNP level is a predictor for developing atrial fibrillation in a general Japanese population: the Hisayama Study (2019)
  • Author(s): Nagata T, Hata J, Sakata S, Oishi E, Honda T, Furuta Y, Ohara T, Yoshida D, Hirakawa Y, Shibata M, Ide T, Kitazono T, Tsutsui H, Ninomiya T
  • Organizer: American Heart Association 2019 Scientific Sessions
  • Int'l Joint Research
• [Presentation] Serum Mac-2 binding protein glycosylation isomer level and the risk of type 2 diabetes in a Japanese community: the Hisayama Study (2019)
  • Author(s): Higashioka M, Hirakawa Y, Yoshinari M, Honda T, Sakata S, Shibata M, Yoshida D, Hata J, Kitazono T, Osawa H, Ninomiya T
  • Organizer: American Diabetes Association 79th Scientific Sessions
  • Int'l Joint Research
• [Presentation] A comparison of the contributions of impaired insulin secretion and insulin resistance to the development of type 2 diabetes in a Japanese community: the Hisayama Study. (2019)
  • Author(s): Yoshinari M, Hirakawa Y, Hata J, Higashioka M, Honda T, Yoshida D, Mukai N, Nakmura U, Kitazono T, Ninomiya T
  • Organizer: American Diabetes Association 79th Scientific Sessions
  • Int'l Joint Research
• [Presentation] 地域住民における潜在的MAC感染症者有病率の検討：久山町研究 (2019)
  • Author(s): 吉田大悟、鷲尾康圭、秦 淳、本田貴紀、柴田舞欧、平川洋一郎、坂田智子、仁木満美子、星野仁彦、二宮利治
  • Organizer: 第26回日本未病システム学会学術総会
• [Presentation] 地域住民における望ましくない食習慣の集積と肥満および腹部肥満の関連：久山町研究 (2019)
  • Author(s): 石田有紀、吉田大悟、本田貴紀、平川洋一郎、柴田舞欧、坂田智子、秦 淳、二宮利治
  • Organizer: 第26回日本未病システム学会学術総会
• [Presentation] 地域住民における総食物繊維と種類別食物繊維が糖尿病発症に及ぼす影響：久山町研究 (2019)
  • Author(s): 木村安美、吉田大悟、平川洋一郎、秦淳、本田貴紀、柴田舞欧、坂田智子、内田和宏、二宮利治
  • Organizer: 第78回日本公衆衛生学会総会
• [Presentation] 地域一般住民における血清small dense LDLコレステロール濃度と頸動脈IMTとの関連：久山町研究 (2019)
  • Author(s): 中西泰之、秦 淳、古田芳彦、坂田智子、大石絵美、平川洋一郎、東岡真由、吉成匡人、吉田大悟、本田貴紀、脇坂義信、吾郷哲朗、北園孝成、二宮利治
  • Organizer: 第6回日本心血管脳卒中学会学術集会
• [Presentation] 高比重リポ蛋白（high-density lipoprotein: HDL）のコレステロール取り込み能が糖尿病発症に与える影響：久山町研究 (2019)
  • Author(s): 平川洋一郎、杜 隆嗣、東岡真由、吉成匡人、本田貴紀、吉田大悟、秦 淳、中村宇大、北園孝成、平田 健一、二宮利治
  • Organizer: 第51回日本動脈硬化学会総会・学術集会
• [Presentation] 地域高齢住民におけるサルコペニアの有病率と危険因子：久山町研究 (2019)
  • Author(s): 中村公隆、吉田大悟、本田貴紀、秦 淳、柴田舞欧、平川洋一郎、古田芳彦、北園孝成、中島康晴、二宮利治
  • Organizer: 第137回西日本整形・災害外科学会学術集会
• [Presentation] 地域高齢住民におけるサルコペニアの有病率と死亡リスク：久山町研究 (2019)
  • Author(s): 中村公隆、吉田大悟、本田貴紀、秦 淳、柴田舞欧、平川洋一郎、古田芳彦、北園孝成、中島康晴、二宮利治
  • Organizer: 第92回日本整形外科学会学術総会
• [Presentation] 本人地域住民における心房細動発症のリスク予測モデルの開発：久山町研究 (2019)
  • Author(s): 秦 淳、坂田智子、永田拓也、平川洋一郎、大石絵美、本田貴紀、吉田大悟、北園孝成、二宮利治
  • Organizer: 第55回日本循環器病予防学会学術集会、
• [Presentation] Serum NT-proBNP level is a useful biomarker for future dementia in a general Japanese elderly population: the Hisayama Study (2018)
  • Author(s): Nagata T, Ohara T, Honda T, Sakata S, Hata J, Hirakawa Y, Yoshida D, Shibata M , Ide T, Tsutsui H, Ninomiya T
  • Organizer: American Heart Association 2018 Scientific Sessions
  • Int'l Joint Research
• [Presentation] 地域高齢者における中年期から老年期の握力低下と認知症発症の関連：久山町研究 (2018)
  • Author(s): 畑部暢三、柴田舞欧、小原知之、大石絵美、吉田大悟、本田貴紀、秦 淳、神庭重信、北園孝成、二宮利治
  • Organizer: 第40回日本生物学的精神医学会
• [Presentation] 地域住民における血清可溶性TREM2値と肥満、インスリン抵抗性の検討：久山町研究 (2018)
  • Author(s): 田中将志、本田貴紀、山陰一、秦 淳、吉田大悟、平川洋一郎、井上隆之、日下部徹、浅原哲子、二宮利治
  • Organizer: 第39回日本肥満学会
• [Presentation] 心血管病リスク予測モデルの開発 -久山町研究- (2018)
  • Author(s): 本田貴紀、吉田大悟、石田有紀、平川洋一郎、秦 淳、岸本裕歩、二宮利治
  • Organizer: 第50回日本動脈硬化学会総会・学術集会
• [Presentation] βアラニン血中濃度と認知症発症の関連：久山町研究 (2018)
  • Author(s): 秦 淳、小原知之、片倉喜範、清水邦義、山下俊太郎、吉田大悟、本田貴紀、平川洋一郎、柴田舞欧、坂田智子、北園孝成、久原 哲、二宮利治
  • Organizer: 第25回日本未病システム学会学術総会
• [Presentation] 心血管病リスク予測モデルの開発と臨床的有用性評価-久山町研究- (2018)
  • Author(s): 本田貴紀、吉田大悟、秦 淳、平川洋一郎、石田有紀、柴田舞欧、坂田智子、北園孝成、二宮利治
  • Organizer: 第25回日本未病システム学会学術総会
• [Presentation] 地域一般住民における食物繊維摂取量と糖尿病発症との関連：久山町研究 (2018)
  • Author(s): 木村安美、吉田大悟、平川洋一郎、秦 淳、本田貴紀、柴田舞欧、坂田智子、内田和宏、二宮利治
  • Organizer: 第29回日本疫学会学術総会
• [Presentation] 地域高齢住民における血清エライジン酸濃度と認知症発症の関連：久山町研究 (2018)
  • Author(s): 本田貴紀、小原知之、篠原正和、秦 淳、杜隆嗣、吉田大悟、石田達郎、平川洋一郎、入野康宏、柴田舞欧、坂田智子、神庭重信、平田健一、二宮利治
  • Organizer: 第29回日本疫学会学術総会
• [Presentation] 地域一般住民における毛髪中水銀濃度とメタボリックシンドローム発症との関連：久山町研究 (2018)
  • Author(s): 小西秀和、吉田大悟、秦 淳、田中昭代、平田美由紀、平川洋一郎、柴田舞欧、本田貴紀、坂田智子、二宮利治
  • Organizer: 第29回日本疫学会学術総会
• [Presentation] 血糖関連指標(HbA1c，グリコアルブミン)と大脳白質病変の関連：久山町研究 (2018)
  • Author(s): 古田芳彦、秦 淳、平林直樹、小原知之、吉田大悟、平川洋一郎、柴田舞欧、本田貴紀、坂田智子、脇坂義信、吾郷哲朗、北園孝成、二宮利治
  • Organizer: 第44回日本脳卒中学会学術集会
• [Presentation] N-terminal pro-B-type natriuretic peptide and risk of dementia in a general Japanese elderly population: the Hisayama Study (2018)
  • Author(s): Nagata T, Ohara T, Hata J, Sakata S, Furuta Y, Yoshida D, Honda T, Hirakawa Y, Ide T, Kanba S, Kitazono T, Tsutsui H, Ninomiya T.
  • Organizer: 第83回日本循環器学会学術集会
• [Remarks] 九州大学大学院医学研究院 衛生・公衆衛生学分野
  • URL: http://www.eph.med.kyushu-u.ac.jp/