| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2020: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2019: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2018: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Outline of Final Research Achievements |
In this study, we examined whether it is possible to regulate the amount of fat in fish muscles by chrono nutritional approach, which treats nutrition from the standpoint of chronobiology. In a two-month feeding experiment, the body mass index (BMI) in the dark feeding group was significantly higher than that in the light feeding group. Although there was significant correlation between the body weight and muscle triglyceride in the light feeding group, its relationship did not find in the dark feeding group. There were significant differences between light and dark groups in the expression of lipid metabolism-related genes, which have E-box sequence that plays an important role in circadian genes on the upstream of their genes. These results suggest that differences in feeding timing may affect intramuscular fat accumulation through an expression of lipid metabolism-related genes.
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