Establishment of fish meat quality improvement by chrono nutritional approach
| Project/Area Number |
18KT0093
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 特設分野 |
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| Research Field |
Agricultural Resources for the Next Generation
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| Research Institution | Nagasaki University |
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Principal Investigator |
HIRASAKA Katsuya 長崎大学, 海洋未来イノベーション機構, 准教授 (70432747)
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| Project Period (FY) |
2018-07-18 – 2021-03-31
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| Project Status |
Completed (Fiscal Year 2020)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2020: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2019: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2018: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 時計遺伝子 / 脂質代謝酵素 / 筋肉 / 中性脂肪 / BMI |
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| Outline of Final Research Achievements |
In this study, we examined whether it is possible to regulate the amount of fat in fish muscles by chrono nutritional approach, which treats nutrition from the standpoint of chronobiology. In a two-month feeding experiment, the body mass index (BMI) in the dark feeding group was significantly higher than that in the light feeding group. Although there was significant correlation between the body weight and muscle triglyceride in the light feeding group, its relationship did not find in the dark feeding group. There were significant differences between light and dark groups in the expression of lipid metabolism-related genes, which have E-box sequence that plays an important role in circadian genes on the upstream of their genes. These results suggest that differences in feeding timing may affect intramuscular fat accumulation through an expression of lipid metabolism-related genes.
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| Academic Significance and Societal Importance of the Research Achievements |
本研究により、給餌タイミングの違いが脂質代謝酵素の発現量を変化させ、魚類筋肉内脂肪蓄積に影響する可能性が示唆された。遺伝子組換えではなく、給餌のタイミングを変えることで魚類筋肉内脂肪含量をコントロールすることは、養殖業を中心とする産業への大きな技術革新を生み出すことになる可能性が示唆される。
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Report
(4 results)
Research Products
(8 results)
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[Journal Article] Effect of dietary fish oil on enhanced inflammation and disturbed lipophagy in white adipose tissue caused by a high fat diet.2020
Author(s)
Saitoh K, Yoshimura T, Sun L, Yang M, Wang Y, Taniyama S, Hara K, Murayama F, Nikawa T, Tachibana K, Hirasaka K.
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Journal Title
Fisheries Science
Volume: 86(1)
Issue: 1
Pages: 187-196
DOI
NAID
Related Report
Peer Reviewed
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