Budget Amount *help |
¥686,270,000 (Direct Cost: ¥527,900,000、Indirect Cost: ¥158,370,000)
Fiscal Year 2011: ¥114,920,000 (Direct Cost: ¥88,400,000、Indirect Cost: ¥26,520,000)
Fiscal Year 2010: ¥114,530,000 (Direct Cost: ¥88,100,000、Indirect Cost: ¥26,430,000)
Fiscal Year 2009: ¥114,530,000 (Direct Cost: ¥88,100,000、Indirect Cost: ¥26,430,000)
Fiscal Year 2008: ¥149,110,000 (Direct Cost: ¥114,700,000、Indirect Cost: ¥34,410,000)
Fiscal Year 2007: ¥193,180,000 (Direct Cost: ¥148,600,000、Indirect Cost: ¥44,580,000)
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Research Abstract |
We analyzed the neural mechanisms underlying cognitive memory from two view-points : one is a local circuit(or processing unit) that generates and transforms encoding/recall signals, and the other is a global cortical network in which local processing units exchange bottom-up or top-down search signals. We identified many functional global networks using effective connectivity measures in BOLD fMRI. We also found a flexible recruitment of interlaminar connectivity in the local circuit of six-layered association cortices, depending on the cognitive demand. Our study provided a breakthrough in understanding of the operation principles of the primate cerebral cortex for cognitive memory.
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