| Budget Amount *help |
¥705,380,000 (Direct Cost: ¥542,600,000、Indirect Cost: ¥162,780,000)
Fiscal Year 2011: ¥140,140,000 (Direct Cost: ¥107,800,000、Indirect Cost: ¥32,340,000)
Fiscal Year 2010: ¥140,140,000 (Direct Cost: ¥107,800,000、Indirect Cost: ¥32,340,000)
Fiscal Year 2009: ¥140,140,000 (Direct Cost: ¥107,800,000、Indirect Cost: ¥32,340,000)
Fiscal Year 2008: ¥141,830,000 (Direct Cost: ¥109,100,000、Indirect Cost: ¥32,730,000)
Fiscal Year 2007: ¥143,130,000 (Direct Cost: ¥110,100,000、Indirect Cost: ¥33,030,000)
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| Research Abstract |
In this project, we have revealed the molecular logics of olfactory map formation. Axons of olfactory sensory neurons (OSNs) are guided to approximate locations in the olfactory bulb by a combination of dorsal-ventral patterning, which is based on anatomical locations of OSNs, and anterior-posterior patterning, which is regulated by cAMP signals whose levels are uniquely determined by odorant receptor species. It was also found that odor information is separately processed by two distinct circuits; one is for hard-wired innate responses, and the other is for memory-based learned behaviors.
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