| Budget Amount *help |
¥50,180,000 (Direct Cost: ¥38,600,000、Indirect Cost: ¥11,580,000)
Fiscal Year 2009: ¥12,740,000 (Direct Cost: ¥9,800,000、Indirect Cost: ¥2,940,000)
Fiscal Year 2008: ¥12,740,000 (Direct Cost: ¥9,800,000、Indirect Cost: ¥2,940,000)
Fiscal Year 2007: ¥24,700,000 (Direct Cost: ¥19,000,000、Indirect Cost: ¥5,700,000)
|
|---|
| Research Abstract |
New carbon-carbon bond cleaving reactions catalyzed by transition metals were developed. Various carbon skeletons were constructed by utilization of these reactions. In particular, enantioselective cleavage of a carbon-carbon bond led to the formation of quaternary chiral carbon centers. For example, six-membered benzolactones having a chiral quaternary center at the benzylic position were synthesized with high enantioselectivity. Indane skeletones having chiral quaternary centers at both benzylic positions were constructed in a stereoselective manner from cyclobutanols with an aryl substituent at the 3-position. A new method to synthesize azulene derivatives, which were attractive as organic materials, was also developed.
|
