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Elucidation of the localization and differentiation capacity of dental pulp stem cells

Research Project

Project/Area Number 19390462
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Morphological basic dentistry
Research InstitutionNiigata University

Principal Investigator

OHSHIMA Hayato  Niigata University, 医歯学系, 教授 (70251824)

Co-Investigator(Kenkyū-buntansha) OHSHIMA Kuniko  新潟大学, 医歯学総合病院, 講師 (80213693)
HONDA Masaki  日本大学, 歯学部, 専任講師 (70361623)
IDA Hiroko  新潟大学, 医歯学系, 准教授 (60293213)
SUZUKI Hironobu  新潟大学, 医歯学系, 助教 (60377190)
Project Period (FY) 2007 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥17,420,000 (Direct Cost: ¥13,400,000、Indirect Cost: ¥4,020,000)
Fiscal Year 2009: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2008: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2007: ¥11,830,000 (Direct Cost: ¥9,100,000、Indirect Cost: ¥2,730,000)
Keywords歯髄組織幹細胞 / BrdU / 象牙芽細胞 / 歯髄 / 窩洞形成 / 歯の再植 / 歯の移植 / 幹細胞ニッチ / 組織幹細胞 / ニッチ / マウス / 骨芽細胞 / ラット / プロモデオキシウリジン
Research Abstract

胎生期ラベリング法により歯髄組織幹細胞をチミジン類似体であるBrdUによりラベルすることに成功し、歯の発生過程での幹細胞の局在と歯の損傷後の幹細胞の分化能を検索した。成熟歯髄において、ラベル細胞は間葉系幹細胞マーカーであるSTRO-1、CD146との共陽性を示し、歯髄中央部血管周囲に密に局在していたことから、同部に歯髄幹細胞ニッチの存在が示唆された。また、歯の損傷後に歯髄組織幹細胞が象牙芽細胞に分化することも明らかとなった。

Report

(4 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • 2007 Annual Research Report
  • Research Products

    (80 results)

All 2010 2009 2008 2007

All Journal Article (31 results) (of which Peer Reviewed: 23 results) Presentation (47 results) Book (2 results)

  • [Journal Article] Pulpal regeneration following allogenic tooth transplantation into mouse maxilla2009

    • Author(s)
      Unno H, Suzuki H, Nakakura-Ohshima K, Jung HS, Ohshima H
    • Journal Title

      Anat Rec (Hoboken) 292(4)

      Pages: 570-579

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Chick tooth induction revisited2009

    • Author(s)
      Cai J, Cho SW, Ishiyama M, Mikami M, Hosoya A, Kozawa Y, Ohshima H, Jung HS
    • Journal Title

      J Exp Zoolog B Mol Dev Evol 312B(5)

      Pages: 465-472

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] The induction of dentin bridge-like structures by constructs of subcultured dental pulp-derived cells and porous HA/TCP in porcine teeth2009

    • Author(s)
      Ando Y, Honda MJ, Ohshima H, Tonomura A, Ohara T, Itaya T, Kagami H, Ueda M
    • Journal Title

      Nagoya J Med Sci 71(1-2)

      Pages: 51-62

    • NAID

      110007025878

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] ERK activation is involved in tooth development via FGF10 signaling2009

    • Author(s)
      Cho KW, Cai J, HY, Hosoya A, Ohshima H, Choi KY, Jung HS
    • Journal Title

      J Exp Zoolog B Mol Dev Evol 312(8)

      Pages: 901-911

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] 今月の表紙:歯髄分化能の最近の知見2009

    • Author(s)
      大島勇人, 高森泰彦, 鈴木啓展, 大島邦子, Jung HS, Cho SW, Cai J
    • Journal Title

      日本歯科評論 69(1)

      Pages: 47-48

    • Related Report
      2009 Final Research Report
  • [Journal Article] 最近のトピックス)歯の損傷後の歯髄修復機構の新規仮説について2009

    • Author(s)
      大島勇人
    • Journal Title

      新潟歯学会雑誌 39(2)

      Pages: 171-176

    • Related Report
      2009 Final Research Report
  • [Journal Article] Pulpal regeneration following allogenic tooth transplantation into mouse maxilla2009

    • Author(s)
      Unno H
    • Journal Title

      Anat Rec 292

      Pages: 570-579

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Chick tooth induction revisited2009

    • Author(s)
      Cai J
    • Journal Title

      J Exp Zoolog B Mol Dev Evol 312B

      Pages: 465-472

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ERK activation is involved in tooth development via FGF10 signaling2009

    • Author(s)
      Cho KW
    • Journal Title

      J Exp Zoolog B Mol Dev Evol 312

      Pages: 901-911

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Overview: developmental biology of Hertwig's epithelial root sheath (HERS) and tooth root formation2008

    • Author(s)
      Ohshima H
    • Journal Title

      J Oral Biosci 50(3

      Pages: 147-153

    • NAID

      10027103900

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Involvement of the klotho protein in dentin formation and mineralization2008

    • Author(s)
      Suzuki H, Amizuka N, Oda K, Noda M, Ohshima H, Maeda T
    • Journal Title

      Anat Rec (Hoboken) 291(2)

      Pages: 183-190

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Histological and elemental analyses of impaired bone mineralization in klotho-deficient mice2008

    • Author(s)
      Suzuki H, Amizuka N, Oda K, Noda M, Ohshima H, Maeda T
    • Journal Title

      J Anat 212(3)

      Pages: 275-285

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Capacity of dental pulp differentiation in mouse molars as demonstrated by allogenic tooth transplantation2008

    • Author(s)
      Takamori Y, Suzuki H, Nakakura-Ohshima K, Cai J, Cho SW, Jung HS, Ohshima H
    • Journal Title

      J Histochem Cytochem 56(12)

      Pages: 1075-1086

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Cell dynamics in the pulpal healing process following cavity preparation in rat molars2008

    • Author(s)
      Harada M, Kenmotsu S, Nakasone N, Nakakura-Ohshima K, Ohshima H
    • Journal Title

      Histochem Cell Biol 130(4)

      Pages: 773-783

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Immunohistochemical analysis of nestin, osteopontin, and proliferating cells in the reparative process of exposed dental pulp capped with mineral trioxide aggregate2008

    • Author(s)
      Kuratate M, Yoshiba K, Shigetani Y, Yoshiba N, Ohshima H, Okiji T
    • Journal Title

      J Endod 34(8)

      Pages: 970-974

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] The relationship between the cusp pattern and plural stem cell compartments in guinea pig cheek teeth by chasing BrdU-labeling2008

    • Author(s)
      Hashimoto E, Nakakura-Ohshima K, Kenmotsu S, Suzuki H, Nakasone N, Saito C, Harada H, Ohshima H
    • Journal Title

      Arch Histol Cytol 71(5)

      Pages: 317-332

    • NAID

      10025096314

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] 歯科再生医療はどこまで到達し, どこへ向かうのか?歯根再生のキーワードとしての「HERS」のメカニズムに迫る2008

    • Author(s)
      大島勇人, 藤原尚樹, Han-Sung Jung, 太田正人, 齋藤正寛, 原田英光
    • Journal Title

      歯界展望 111(5)

      Pages: 953-962

    • Related Report
      2009 Final Research Report
  • [Journal Article] 歯胚移植の可能性:歯冠・歯根の成長にかかわる組織誘導のメカニズム-寺田・村山論文に寄せて2008

    • Author(s)
      大島勇人
    • Journal Title

      日本歯科評論 68(12)

      Pages: 117-122

    • NAID

      40016352709

    • Related Report
      2009 Final Research Report
  • [Journal Article] Capacity of dental pulp differentiation in mouse molars as demonstrated by allogenic tooth transplantation2008

    • Author(s)
      Takamori Y
    • Journal Title

      Journal of Histochemistry and Cytochemistry 1075

      Pages: 1075-1086

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cell dynamics in the pulpal healing process following cavity preparation in rat molars2008

    • Author(s)
      Harada M
    • Journal Title

      Histocheraistry and Cell Biology 130

      Pages: 773-783

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Overview : developmental biology of Hertwig' s epithelial root sheath (HERS) and tooth root formation2008

    • Author(s)
      Ohshima H
    • Journal Title

      Journal of Oral Biosciences 50

      Pages: 147-153

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 歯の損傷後の歯髄修復機構2007

    • Author(s)
      大島勇人
    • Journal Title

      歯科臨床研究 4(1

      Pages: 49-57

    • Related Report
      2009 Final Research Report
  • [Journal Article] 歯髄反応を生物学的に考える2007

    • Author(s)
      大島勇人
    • Journal Title

      STR療法学会雑誌

      Pages: 5-13

    • Related Report
      2009 Final Research Report
  • [Journal Article] The effect of cortical activation on orthodontic tooth movement2007

    • Author(s)
      Cho KW, Cho SW, Oh CO, Ryu YK, Ohshima H, Jung HS
    • Journal Title

      Oral Diseases 13(3)

      Pages: 314-319

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] The primary enamel knot determines the position of the first buccal cusp in developing mice molars2007

    • Author(s)
      Cho SW, Lee HA, Cai J, Lee MJ, Ohshima H, Jung HS
    • Journal Title

      Differentiation 75(5)

      Pages: 441-451

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Rat wct mutation induces a hypo-mineralization form of amelogenesis imperfecta and cyst formation in molar teeth2007

    • Author(s)
      Osawa M, Kenmotsu S, Masuyama T, Taniguchi K, Uchida T, Saito C, Ohshima H
    • Journal Title

      Cell Tissue Res 330(1)

      Pages: 97-109

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Influence of extended operation time and of occlusal force on determination of pulpal healing pattern in replanted mouse molars2007

    • Author(s)
      Hasegawa T, Suzuki H, Yoshie H, Ohshima H
    • Journal Title

      Cell Tissue Res 329(2)

      Pages: 259-272

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Rat wct mutation prevents differentiation of maturation-stage ameloblasts resulting in hypo-mineralization in incisor teeth2007

    • Author(s)
      Osawa M, Kenmotsu S, Masuyama T, Taniguchi K, Uchida T, Saito C, Ohshima H
    • Journal Title

      Histochem Cell Biol 128(3)

      Pages: 183-193

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] 歯の損傷後の歯髄修復機構2007

    • Author(s)
      大島勇人
    • Journal Title

      歯科臨床研究 4

      Pages: 49-57

    • Related Report
      2007 Annual Research Report
  • [Journal Article] 歯髄反応を生物学的に考える2007

    • Author(s)
      大島勇人
    • Journal Title

      LSTR療法学会雑誌

      Pages: 5-13

    • Related Report
      2007 Annual Research Report
  • [Journal Article] Influence of extended operation time and of occlusal force on determination of pulpal healing pattern in replanted mouse molars2007

    • Author(s)
      Hasegawa T
    • Journal Title

      Cell and Tissue Research 329

      Pages: 259-272

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Presentation] 窩洞形成と歯髄反応2010

    • Author(s)
      大島勇人
    • Organizer
      岩手医科大学歯学部特別講義
    • Place of Presentation
      盛岡
    • Year and Date
      2010-01-12
    • Related Report
      2009 Final Research Report
  • [Presentation] ラット臼歯象牙質形成における歯髄毛細血管と基質形成・石灰化との相関について2010

    • Author(s)
      大島勇人, 中富満城, 中川英蔵, 石川裕子, 監物新一, 依田浩子
    • Organizer
      第115回日本解剖学会総会・全国学術集会
    • Place of Presentation
      盛岡
    • Related Report
      2009 Final Research Report
  • [Presentation] 象牙質成長線を生物学的に考える2010

    • Author(s)
      大島勇人
    • Organizer
      115回日本解剖学会総会研究集会・懇話会「組織形態形成における周期性のメカニズムとその意義」
    • Place of Presentation
      盛岡
    • Related Report
      2009 Final Research Report
  • [Presentation] 胎生期BrdUラべリング法を用いたマウス顎骨への歯の他家移植後の歯髄・歯周組織再生過程におけるlabel-retaining cellsの動態について2009

    • Author(s)
      武藤徳子, 石井信之, 大島勇人
    • Organizer
      神奈川歯科大学学会第44回総会
    • Place of Presentation
      横須賀
    • Year and Date
      2009-12-05
    • Related Report
      2009 Final Research Report
  • [Presentation] 外的刺激に対する歯髄反応の特殊性と歯髄分化能2009

    • Author(s)
      大島勇人
    • Organizer
      日本大学歯学部大学院特別セミナー
    • Place of Presentation
      東京
    • Year and Date
      2009-11-06
    • Related Report
      2009 Final Research Report
  • [Presentation] 電子顕微鏡で解き明かす歯の損傷後の歯髄反応2009

    • Author(s)
      大島勇人
    • Organizer
      日本大学松戸歯学部電顕講習会
    • Place of Presentation
      松戸
    • Year and Date
      2009-10-30
    • Related Report
      2009 Final Research Report
  • [Presentation] Putative dental pulp stem cells in growing teeth & their regenerative capacity2009

    • Author(s)
      Ohshima H
    • Organizer
      2nd TERMIS World Congress in conjunction with 2009 Seoul Stem Cell Symposium
    • Place of Presentation
      ソウル(韓国)
    • Year and Date
      2009-09-03
    • Related Report
      2009 Annual Research Report
  • [Presentation] Responses of dental pulp stem cells against exogenous stimuli2009

    • Author(s)
      Ohshima H
    • Organizer
      15th APEC & 7th KAE-JEA Joint Meeting
    • Place of Presentation
      東京
    • Year and Date
      2009-04-25
    • Related Report
      2009 Annual Research Report
  • [Presentation] 歯の発生おける歯髄幹細胞の局在と損傷後の再生能2009

    • Author(s)
      大島勇人
    • Organizer
      岡山大学大学院医歯薬学総合研究科歯と顔の発生・再生シンポジウム
    • Place of Presentation
      岡山
    • Year and Date
      2009-03-27
    • Related Report
      2009 Final Research Report
  • [Presentation] ラット臼歯歯髄に存在する組織幹細胞 : BrdUラベル細胞とSP細胞との相関について2009

    • Author(s)
      大島勇人
    • Organizer
      第8回日本再生医療学会総会
    • Place of Presentation
      東京
    • Year and Date
      2009-03-06
    • Related Report
      2008 Annual Research Report
  • [Presentation] Mapping of putative dental pulp stem cells in growing teeth and their regenerative capacity after injuries2009

    • Author(s)
      Ohshima H
    • Organizer
      Seminar in Yonsei University
    • Place of Presentation
      ソウル, 韓国
    • Year and Date
      2009-02-12
    • Related Report
      2009 Final Research Report
  • [Presentation] Periodontal formation following allogenic tooth germ transplantation into mouse maxilla2009

    • Author(s)
      Nakagawa E, Ida H, Yoshie H, Ohshima H
    • Organizer
      2nd Meeting of IADR Pan Asian Pacific Federation (PAPF) and the 1st Meeting of IADR Asia/Pacific Region (APR)
    • Place of Presentation
      Wuhan, Hubei Province, China
    • Related Report
      2009 Final Research Report
  • [Presentation] マウス臼歯発生過程における歯髄組織幹細胞の局在2009

    • Author(s)
      石川裕子, 依田浩子, 大島邦子, 本田雅規, 大島勇人
    • Organizer
      第51回歯科基礎医学会学術大会・総会
    • Place of Presentation
      新潟
    • Related Report
      2009 Final Research Report
  • [Presentation] マウス顎骨への歯の他家移植後の歯髄・歯周組織再生過程における組織幹細胞の動態について2009

    • Author(s)
      武藤徳子, 中川英蔵, 依田浩子, 石井信之, 大島勇人
    • Organizer
      第51回歯科基礎医学会学術大会・総会
    • Place of Presentation
      新潟
    • Related Report
      2009 Final Research Report
  • [Presentation] マウス臼歯再植・移植後の歯髄治癒過程におけるGM-CSFおよびオステオポンチンの役割について2009

    • Author(s)
      斎藤浩太郎, 依田浩子, 石川裕子, 大島勇人
    • Organizer
      第51回歯科基礎医学会学術大会・総会
    • Place of Presentation
      新潟
    • Related Report
      2009 Final Research Report
  • [Presentation] Putative dental pulp stem cells in growing teeth, their regenerative capacity2009

    • Author(s)
      Ohshima H
    • Organizer
      2nd TERMIS World Congress in conjunction with 2009 Seoul Stem Cell Symposium
    • Place of Presentation
      Seoul, Republic of Korea
    • Related Report
      2009 Final Research Report
  • [Presentation] 歯髄幹細胞と歯の損傷後の歯髄修復機構2009

    • Author(s)
      大島勇人
    • Organizer
      歯胚再生コンソーシアム, 岩手医科大学歯学部オープンリサーチ主催「若手研究セミナー
    • Place of Presentation
      岩手山焼走り国際交流村
    • Related Report
      2009 Final Research Report
  • [Presentation] Responses of dental pulp stem cells against exogenous stimuli2009

    • Author(s)
      Ohshima H
    • Organizer
      15th APEC, 7th KAE-JEA Joint Meeting
    • Place of Presentation
      Tokyo, Japan
    • Related Report
      2009 Final Research Report
  • [Presentation] マウス舌下部への臼歯および歯冠部の他家移植後の歯髄組織幹細胞の動態と硬組織形成能について2009

    • Author(s)
      大島勇人, 石川裕子, 依田浩子, 鈴木啓展, 監物新一, 大島邦子
    • Organizer
      第114回日本解剖学会総会・全国学術集会
    • Place of Presentation
      岡山
    • Related Report
      2009 Final Research Report
  • [Presentation] ラット臼歯歯髄に存在する組織幹細胞:BrdUラベル細胞とSP細胞との相関について2009

    • Author(s)
      大島勇人, 石川裕子, 依田浩子, 鈴木啓展, 監物新一, 大島邦子, 本田雅規, 石井有実子, 渡辺信和
    • Organizer
      第8回日本再生医療学会総会
    • Place of Presentation
      東京
    • Related Report
      2009 Final Research Report
  • [Presentation] Mapping of putative dental pulp stem cells in growing teeth and their regenerative capacity after injuries2009

    • Author(s)
      Ohshima H
    • Organizer
      平成20年度戦略的研究基盤形成支援事業研究集会
    • Place of Presentation
      東京
    • Related Report
      2009 Final Research Report
  • [Presentation] オーバービュー:象牙芽細胞と骨芽細胞の違いを考える2009

    • Author(s)
      大島勇人
    • Organizer
      第113回日本解剖学会総会・全国学術集会
    • Place of Presentation
      大分
    • Related Report
      2009 Final Research Report
  • [Presentation] Dental pulp stem cells and their responses to tooth injuries2008

    • Author(s)
      Ohshima H
    • Organizer
      歯胚再生コンソーシアム座談会
    • Place of Presentation
      花巻
    • Year and Date
      2008-09-28
    • Related Report
      2009 Final Research Report
  • [Presentation] Cell dynamics in the process of pulpal healing following tooth injuries2008

    • Author(s)
      Ohshima H
    • Organizer
      Seminar in Kyungpook University
    • Place of Presentation
      大邱, 韓国
    • Year and Date
      2008-08-27
    • Related Report
      2009 Final Research Report
  • [Presentation] 電子顕微鏡で明らかになった窩洞形成後の歯髄反応2008

    • Author(s)
      大島勇人
    • Organizer
      日本大学松戸歯学部電顕講習会
    • Place of Presentation
      松戸
    • Year and Date
      2008-08-20
    • Related Report
      2009 Final Research Report
  • [Presentation] ラット臼歯歯髄組織幹細胞の歯の損傷後の分化能について2008

    • Author(s)
      石川裕子, 大島邦子, 大島勇人
    • Organizer
      平成20年度新潟歯学会第1回例会
    • Place of Presentation
      新潟
    • Year and Date
      2008-07-19
    • Related Report
      2009 Final Research Report
  • [Presentation] 歯の再生の現状と課題2008

    • Author(s)
      大島勇人
    • Organizer
      朝日大学歯学部大学院特別講義
    • Place of Presentation
      岐阜
    • Year and Date
      2008-07-11
    • Related Report
      2009 Final Research Report
  • [Presentation] マウス臼歯舌下部への他家移植後の歯髄組織幹細胞の動態と硬組織形成能について2008

    • Author(s)
      大島勇人, 石川裕子, 鈴木啓展, 監物新一, 大島邦子
    • Organizer
      第50回歯科基礎医学会学術大会・総会
    • Place of Presentation
      東京
    • Related Report
      2009 Final Research Report
  • [Presentation] ラット臼歯歯髄に存在する組織幹細胞について2008

    • Author(s)
      大島勇人, 石川裕子, 鈴木啓展, 監物新一, 大島邦子, 本田雅規, 石井有実子, 渡辺信和
    • Organizer
      第113回日本解剖学会総会・全国学術集会
    • Place of Presentation
      大分
    • Related Report
      2009 Final Research Report 2007 Annual Research Report
  • [Presentation] Responses of dental pulp stem cells against exogenous stimuli in rat and mouse molars2008

    • Author(s)
      Ishikawa Y, Nakakura-Ohshima K, Kenmotsu S, Suzuki H, Jung HS, Honda MJ, Ohshima H
    • Organizer
      Gordon Research Conferences: Craniofacial Morphogenesis, Tissue Regeneration
    • Place of Presentation
      Lucca (Barga), Italy
    • Related Report
      2009 Final Research Report
  • [Presentation] 歯髄の再生2007

    • Author(s)
      大島勇人
    • Organizer
      岩手医科大学歯学部オープンリサーチ・プロジェクト平成19年度第5回セミナー
    • Place of Presentation
      盛岡
    • Year and Date
      2007-10-30
    • Related Report
      2009 Final Research Report
  • [Presentation] 電子顕微鏡で解き明かす歯の発生生物学2007

    • Author(s)
      大島勇人
    • Organizer
      日本大学松戸歯学部電顕講習会
    • Place of Presentation
      松戸
    • Year and Date
      2007-10-26
    • Related Report
      2009 Final Research Report
  • [Presentation] 歯の再生の現状と展望2007

    • Author(s)
      大島勇人
    • Organizer
      平成19年度新潟大学教室系技術職員専門研修
    • Place of Presentation
      新潟
    • Year and Date
      2007-08-27
    • Related Report
      2009 Final Research Report
  • [Presentation] 外的刺激に対する歯髄反応の特殊性と分化能2007

    • Author(s)
      大島勇人
    • Organizer
      第32回峠の会
    • Place of Presentation
      山形
    • Year and Date
      2007-08-03
    • Related Report
      2009 Final Research Report
  • [Presentation] 歯髄には象牙芽細胞および骨芽細胞への分化能をもつ細胞群が存在する2007

    • Author(s)
      高森泰彦, 鈴木啓展, 大島邦子, 大島勇人
    • Organizer
      平成19年度新潟歯学会第1回例会
    • Place of Presentation
      新潟
    • Year and Date
      2007-07-14
    • Related Report
      2009 Final Research Report
  • [Presentation] マウス顎骨への歯の他家移植後の歯髄再生過程と分化能2007

    • Author(s)
      海野秀基, 鈴木啓展, 大島邦子, 大島勇人
    • Organizer
      平成19年度新潟歯学会第1回例会
    • Place of Presentation
      新潟
    • Year and Date
      2007-07-14
    • Related Report
      2009 Final Research Report
  • [Presentation] ラット臼歯窩洞形成後の歯髄における細胞増殖と分化との関係について2007

    • Author(s)
      原田政広, 大島邦子, 大島勇人
    • Organizer
      平成19年度新潟歯学会第1回例会
    • Place of Presentation
      新潟
    • Year and Date
      2007-07-14
    • Related Report
      2009 Final Research Report
  • [Presentation] 世界における歯の再生研究の動向と歯胚再生コンソーシアムの展開2007

    • Author(s)
      大島勇人
    • Organizer
      共同記者会見:歯胚再生コンソーシアムの新たな展開について
    • Place of Presentation
      東京
    • Year and Date
      2007-06-03
    • Related Report
      2009 Final Research Report
  • [Presentation] Cell dynamics in the process of pulpal healing following tooth injuries2007

    • Author(s)
      Ohshima H
    • Organizer
      International Symposium on Molecular Destruction and Reconstruction of the Dentin/Pulp Complex and Its Surrounding Tissues (the COE program:“Frontier Research on Molecular Destruction and Reconstruction of Tooth and Bone", Tokyo Medical and Dental University)
    • Place of Presentation
      Tokyo, Japan
    • Year and Date
      2007-03-05
    • Related Report
      2009 Final Research Report
  • [Presentation] Dental pulp regeneration after exogenous stimuli: its relation to the dental pulp stem cells2007

    • Author(s)
      Ohshima H
    • Organizer
      Jang JH, Uemura T: Tooth regeneration, 1st Asian Biomaterials Congress (1st ABMC) Integrated Congress of 6th Asian International Symposium on Biomaterials and 8th Asian Symposium on Biomedical Materials
    • Place of Presentation
      Tsukuba, Japan
    • Related Report
      2009 Final Research Report
  • [Presentation] 歯の損傷後の歯髄修復機構の解明から歯の再生研究への展開2007

    • Author(s)
      大島勇人
    • Organizer
      解明から歯の再生研究への展開.第5回日本再生歯科医学会学術大会および総会, シンポジウム1
    • Place of Presentation
      東京
    • Related Report
      2009 Final Research Report
  • [Presentation] Chick tooth' revisited2007

    • Author(s)
      Cai J, Cho SW, Ishiyama M, Mikami M, Kozawa Y, Ohshima H, Jung HS
    • Organizer
      IXth International Conference on Tooth Morphogenesis and Differentiatio
    • Place of Presentation
      Zurich, Switzerland
    • Related Report
      2009 Final Research Report
  • [Presentation] Responses of dental pulp stem cells against exogenous stimuli2007

    • Author(s)
      Ishikawa Y, Nakakura-Ohshima K, Kenmotsu S, Suzuki H, Jung HS, Ohshima H
    • Organizer
      IXth International Conference on Tooth Morphogenesis and Differentiation
    • Place of Presentation
      Zurich, Switzerland
    • Related Report
      2009 Final Research Report
  • [Presentation] マウス臼歯再植および他家移植後の歯髄組織幹細胞の動態と硬組織形成能について2007

    • Author(s)
      大島勇人, 石川裕子, 鈴木啓展, 大島邦子
    • Organizer
      第49回歯科基礎医学会学術大会・総会
    • Place of Presentation
      札幌
    • Related Report
      2009 Final Research Report
  • [Presentation] ラット臼歯歯髄組織幹細胞の局在と歯の損傷後の分化能について2007

    • Author(s)
      石川裕子, 大島邦子, 大島勇人
    • Organizer
      第49回歯科基礎医学会学術大会・総会
    • Place of Presentation
      札幌
    • Related Report
      2009 Final Research Report
  • [Presentation] 顎骨への歯の他家移植実験を利用した歯髄分化能の検索2007

    • Author(s)
      大島勇人, 海野秀基, 鈴木啓展, 監物新一, 大島邦子, Cho SW, Cai J, Jung HS
    • Organizer
      第112回日本解剖学会総会・全国学術集会
    • Place of Presentation
      大阪
    • Related Report
      2009 Final Research Report
  • [Presentation] Factors to determine the different healing patterns in replanted teeth2007

    • Author(s)
      Hasegawa T, Suzuki H, Yoshie H, Ohshima H
    • Organizer
      85th General Session and Exhibition of IADR
    • Place of Presentation
      New Orleans, Louisiana
    • Related Report
      2009 Final Research Report
  • [Book] エナメル質,その形成,構造,組成と進化,再生2009

    • Author(s)
      脇田稔
    • Total Pages
      286
    • Publisher
      蓼科印刷株式会社
    • Related Report
      2009 Annual Research Report
  • [Book] カラーアトラス口腔組織発生学2009

    • Author(s)
      磯川桂太郎
    • Total Pages
      134
    • Publisher
      わかば出版
    • Related Report
      2008 Annual Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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