Response mechanism of anti-oxidant enzymes with bacterial infection in fishes-Cell biological approach -
| Project/Area Number |
19580236
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Fisheries chemistry
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| Research Institution | Nagasaki University |
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Principal Investigator |
OSATOMI Kiyoshi Nagasaki University, 水産学部, 教授 (40253702)
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| Co-Investigator(Kenkyū-buntansha) |
ODA Tatsuya 長崎大学, 水産学部, 教授 (60145307)
HARA Kenji 長崎大学, 水産学部, 教授 (10039737)
TACHIBANA Katsuyasu 長崎大学, 水産学部, 教授 (20171712)
KANAI Kinya 長崎大学, 水産学部, 教授 (40145222)
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| Project Period (FY) |
2007 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2008: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2007: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | 抗酸化酵素 / 活性酸素 / 魚病細菌 / 酸化ストレス / 細胞培養系 / 培養細胞系 / クローニング / 遺伝子構造 |
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| Research Abstract |
In this study, we demonstrated that high virulent strain (NUF251) of Edwardsiella tarda has an ability to prevent the production of reactive oxygen species (ROS) by macrophages, and is even capable of surviving and multiplying within Japanese flounder peritoneal macrophages, where the low virulent strain (NUF194) has no ability.
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Report
(4 results)
Research Products
(8 results)
