| Project/Area Number |
19592277
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
補綴理工系歯学
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| Research Institution | Fukuoka College of Health Sciences |
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Principal Investigator |
INOUE Yusuke Fukuoka College of Health Sciences, 歯科衛生学科, 准教授 (20105688)
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| Co-Investigator(Kenkyū-buntansha) |
FUKUSHIMA Tadao 福岡歯科大学, 歯学部, 准教授 (80084250)
HAYAKAWA Tohru 鶴見大学, 歯学部, 教授 (40172994)
OKAHATA Yoshio 東京工業大学, 大学院・生命理工学研究科, 教授 (80038017)
KAWAGUCHI Minoru 福岡歯科大学, 歯学部, 講師 (10122780)
TANIGUCHI Kunihisa 福岡歯科大学, 歯学部, 教授 (90105685)
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| Project Period (FY) |
2007 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2008: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2007: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | 生体材料 / DNA / キトサン / GTR / GBR / メンブレン |
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| Research Abstract |
The characteristics of experimental multi-layer GTR or GBR membrane made from DNA, chitosan and amphiphilic lipid was investigated. And also the possibility of multi-layer formation on the DNA/chitosan/lipid complex film or GTR membrane on the market or titan plate was investigated. DNA/chitosan/lipid complex multilayer membrane showed antibacterial activity against Porphyromonas gingivalis and Staphyrococcus aureus, and antifungal activity against Candida albicans. The DNA/chitosan/lipid complex multilayer formed on the DNA/chitosan/lipid complex film or GTR membrane, and showed antibacterial activity and antifungal activity as DNA/chitosan/lipid complex multilayer membrane showed.
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