| Budget Amount *help |
¥21,450,000 (Direct Cost: ¥16,500,000、Indirect Cost: ¥4,950,000)
Fiscal Year 2009: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2008: ¥7,540,000 (Direct Cost: ¥5,800,000、Indirect Cost: ¥1,740,000)
Fiscal Year 2007: ¥8,450,000 (Direct Cost: ¥6,500,000、Indirect Cost: ¥1,950,000)
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| Research Abstract |
We recently pay attention to the risk of the adverse effects of environmental chemical exposure on child health. This study was aimed to determine the effects of developmental exposure to toluene, a volatile organic compound widely used as an industrial solvent, on the sexual differentiation of the brain. As the results, it was found that exposure to toluene during developing period decreased blood testosterone levels of fetal male rats and the volume of the SDN-POA, a sexually dimorphic nucleus, of male rats in adulthood.
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