Genetic reconstitution of autoimmune diseases in mice.
| Project/Area Number |
19689012
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| Research Category |
Grant-in-Aid for Young Scientists (A)
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| Allocation Type | Single-year Grants |
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| Research Field |
Immunology
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| Research Institution | The University of Tokushima |
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Principal Investigator |
OKAZAKI Taku 徳島大学, 疾患ゲノム研究センター, 教授 (00362468)
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| Project Period (FY) |
2007 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥25,220,000 (Direct Cost: ¥19,400,000、Indirect Cost: ¥5,820,000)
Fiscal Year 2009: ¥8,190,000 (Direct Cost: ¥6,300,000、Indirect Cost: ¥1,890,000)
Fiscal Year 2008: ¥8,190,000 (Direct Cost: ¥6,300,000、Indirect Cost: ¥1,890,000)
Fiscal Year 2007: ¥8,840,000 (Direct Cost: ¥6,800,000、Indirect Cost: ¥2,040,000)
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| Keywords | 遺伝子 / 細胞 / 実験動物 / 自己免疫疾患 / 連鎖解析 / I型糖尿病 / 免疫学 / ゲノム / 自己免疫寛容 / 末梢神経炎 / 多遺伝子疾患 |
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| Outline of Final Research Achievements |
We have identified several autoimmune susceptible loci by genetic linkage analyses on animal models of type I diabetes, peripheral neuropathy, and myocarditis. We have also succeeded in reconstituting type I diabetes on the disease-resistant strain by introducing diabetes susceptible loci.
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Report
(3 results)
Research Products
(19 results)
