| Project/Area Number |
19780228
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Applied veterinary science
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| Research Institution | Hokkaido Institute of Public Health |
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Principal Investigator |
GOTO Akiko Hokkaido Institute of Public Health, 感染症センター生物科学部, 研究職員 (60414322)
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| Research Collaborator |
YAMANO Kimiaki 北海道立衛生研究所, 感染症センター生物科学部, 感染病理科長 (40435566)
YAGI Kinpei 北海道立衛生研究所, 感染症センター生物科学部, 主任研究員 (70414323)
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| Project Period (FY) |
2007 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥3,180,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥480,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2007: ¥1,100,000 (Direct Cost: ¥1,100,000)
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| Keywords | 人獣共通感染症 / 多包性エキノコックス症 / 抗体医薬 / 寄生虫 / 多包条虫 / 分子生物学 |
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| Research Abstract |
Alveolar echinococcosis, which is caused by the larva of E. multilocularis (Em), is a life-threatening zoonotic parasitosis in humans. To develop the diagnosis and antibody drug for treatment against alveolar echinococcosis, I tried to construct some recombinant monoclonal antibodies from Em-infected mouse by using molecular biological methods. In result, four recombinant monoclonal antibodies reacting with Em antigen were constructed.
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