Antinociceptive effects of glycine-and GABA-transporter inhibitors in neuropathic pain models
| Project/Area Number |
19791095
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Anesthesiology/Resuscitation studies
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| Research Institution | University of Occupational and Environmental Health, Japan |
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Principal Investigator |
HARA Koji University of Occupational and Environmental Health, Japan, 医学部, 講師 (20331001)
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| Project Period (FY) |
2007 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥570,000)
Fiscal Year 2009: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2008: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2007: ¥1,300,000 (Direct Cost: ¥1,300,000)
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| Keywords | 神経障害性疼痛 / グリシントランスポーター阻害剤 / GABAトランスポーター阻害剤 / 疼痛行動実験 / 坐骨神経結紮モデル / 抗侵害作用 / 運動協調機能 / 神経因性疼痛 / 糖尿病性ニューロパチーモデル / グリシントランスポーター / GABAトランスポーター / 坐骨神経部分結紮モデル |
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| Research Abstract |
Inhibitory neurotransmitter transporters are promising targets for treatments of acute, inflammatory, and neuropathic pains, and glycinergic neurons may be key component of modulating nociceptive transmittion.
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Report
(4 results)
Research Products
(4 results)
