A genome-wide association study of mandibular prognathism using pooled DNA typing
| Project/Area Number |
19791561
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Orthodontic/Pediatric dentistry
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| Research Institution | Hokkaido University |
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Principal Investigator |
KAJII Takashi Hokkaido University, 大学院・歯学研究科, 助教 (60322822)
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| Project Period (FY) |
2007 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥2,910,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥510,000)
Fiscal Year 2009: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2008: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2007: ¥700,000 (Direct Cost: ¥700,000)
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| Keywords | 歯科矯正学 / 基礎ゲノム科学 / ヒトゲノムDNA / ゲノムワイド遺伝的相関解析 / pooled DNAタイピング / 骨格性下顎前突症 / pooled DNAタピング |
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| Research Abstract |
The pooled DNA of 140 of mandibular prognathism (case) group and that of 180 of healthy (control) group were prepared. We conducted a genome-wide association study of mandibular prognathism using micro-satellite markers and the pooled DNA. The first screening of genome-wide association study focused 750 of loci associated with mandibular prognathism from 30,000 of total loci.
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Report
(4 results)
Research Products
(14 results)
