The interaction of salivary proteins and GTFase.

• Project/Area Number: 19791602
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Orthodontic/Pediatric dentistry
• Research Institution: The Nippon Dental University
• Principal Investigator: TANAKA Satoshi The Nippon Dental University, 新潟生命歯学部, 講師 (00350166)
• Project Period (FY): 2007 – 2009
• Project Status: Completed (Fiscal Year 2009)
• Budget Amount: ¥3,820,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥420,000); Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2008: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2007: ¥2,000,000 (Direct Cost: ¥2,000,000)
• Keywords: GTFase / S.mutans / 唾液タンパク質 / GTF / 齲蝕 / リゾチーム / S.sobrinus / アミラーゼ / St. mutans / St.mutans

Research Abstract

The GTFase which is produced by S.mutans (cariogenic bacteria), and salivary proteins (lysozyme) were analyzed by inhibition assay . The SNPs of lysozyme also were analyzed for caries susceptibility.