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Different role of REM and NonREM sleep for episodic memory modification

Research Project

Project/Area Number 19H01776
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Review Section Basic Section 10040:Experimental psychology-related
Research InstitutionNational Institute of Advanced Industrial Science and Technology

Principal Investigator

Kaida Kosuke  国立研究開発法人産業技術総合研究所, 情報・人間工学領域, 主任研究員 (80586264)

Project Period (FY) 2019-04-01 – 2022-03-31
Project Status Completed (Fiscal Year 2022)
Budget Amount *help
¥17,940,000 (Direct Cost: ¥13,800,000、Indirect Cost: ¥4,140,000)
Fiscal Year 2021: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2020: ¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
Fiscal Year 2019: ¥11,440,000 (Direct Cost: ¥8,800,000、Indirect Cost: ¥2,640,000)
Keywords記憶 / 睡眠
Outline of Research at the Start

本研究では、記憶の変容率は、ノンレム睡眠後よりも、レム睡眠後に大きいことを明らかにする。記憶は、再生されると変容する性質を持っている。記憶は、覚醒中だけでなく睡眠中にも再生されるので、睡眠中にも変容している可能性が高い。特に、レム睡眠中の脳の状態は覚醒中に近く、記憶は夢として再生されやすいため、「記憶の変容は、ノンレム睡眠中と比べて、レム睡眠中で大きい」(仮説1)可能性がある。また、記憶は「ノンレム睡眠中に固定され、レム睡眠中に変容される」(仮説2)というサイクルを通して形成されている可能性がある。本研究では、ヒトを対象として、上記仮説1および2を検証する。

Outline of Final Research Achievements

The purpose of this study was to investigate the process of memory formation during sleep. In order to examine the consolidation and modification of memory, we used the split-half method, which divides nighttime sleep into the first half (non-REM sleep dominant) and the second half (REM sleep dominant). As memory tasks, an associative memory task and a hindsight bias task were adopted. The use of the hindsight bias task in sleep research is original in this study. As a result of the research, it was confirmed that memory consolidation more occurred during non-REM sleep than REM sleep, and memory alteration more occurred during REM sleep than non-REM sleep. In addition, it was found that memory consolidation occurs within a few hours, but memory transformation takes several days. This is one of the main results of this study, as no other study has quantified memory modification during sleep as hindsight bias.

Academic Significance and Societal Importance of the Research Achievements

本研究の結果、レム睡眠中に記憶の変容が生じている可能性が高いことが明らかになった。記憶の変容は、誤った意思決定の原因となり得る一方で、自然環境や社会環境へ合わせて記憶を変化適応させ、精神状態を良好に保つためになくてはならない機能でもある。その重要な機能にレム睡眠が関与していることが明らかとなったことの学術的意義は大きい。また、本研究の結果は、記憶の変容を伴う心理療法(認知行動療法など)の効果を促進するためにもレム睡眠が重要であることを示唆しており、この知見が社会に及ぼす意義は深いと考えられる。

Report

(4 results)
  • 2022 Final Research Report ( PDF )
  • 2021 Annual Research Report
  • 2020 Annual Research Report
  • 2019 Annual Research Report
  • Research Products

    (7 results)

All 2023 2022 2020 2019

All Journal Article (3 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 3 results,  Open Access: 2 results) Presentation (1 results) Book (3 results)

  • [Journal Article] Memory load of information encoded amplifies the magnitude of hindsight bias.2023

    • Author(s)
      Kosuke Kaida, Naoko Kaida
    • Journal Title

      Plos One

      Volume: 18

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Discrepancies between beliefs and practices on sleep as a factor of insomnia and negative feelings.2022

    • Author(s)
      Kosuke Kaida, Naoko Kaida
    • Journal Title

      Psychological Reports

      Volume: 125 Pages: 2029-2051

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Counteracting effect of verbal ratings of sleepiness on dual task interference.2020

    • Author(s)
      Kosuke KAIDA, Takashi ABE, Sunao IWAKI
    • Journal Title

      Industrial Health

      Volume: 58 Pages: 443-450

    • NAID

      130007923645

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Presentation] 記憶の変容量を計測するための「記憶変容課題」の開発と妥当性の検討2019

    • Author(s)
      甲斐田幸佐
    • Organizer
      日本心理学会
    • Related Report
      2019 Annual Research Report
  • [Book] 健康・医療・福祉のための睡眠検定ハンドブック up to date(10章 睡眠と記憶・学習)2022

    • Author(s)
      甲斐田幸佐
    • Total Pages
      398
    • Publisher
      全日本病院出版会
    • ISBN
      4865198113
    • Related Report
      2021 Annual Research Report
  • [Book] 睡眠学「8章 精神運動機能」2020

    • Author(s)
      甲斐田幸佐
    • Total Pages
      712
    • Publisher
      朝倉書店
    • ISBN
      4254301200
    • Related Report
      2020 Annual Research Report
  • [Book] 睡眠学「10章 睡眠と記憶・学習」2020

    • Author(s)
      甲斐田幸佐
    • Total Pages
      712
    • Publisher
      朝倉書店
    • ISBN
      4254301200
    • Related Report
      2020 Annual Research Report

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Published: 2019-04-18   Modified: 2024-01-30  

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