• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Long-term Effect of Light Exposure on Health Outcomes

Research Project

Project/Area Number 19H03903
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Review Section Basic Section 58030:Hygiene and public health-related: excluding laboratory approach
Research InstitutionNara Medical University

Principal Investigator

OBAYASHI KENJI  奈良県立医科大学, 医学部, 特任准教授 (30596656)

Co-Investigator(Kenkyū-buntansha) 佐伯 圭吾  奈良県立医科大学, 医学部, 教授 (60364056)
根来 宏光  筑波大学, 医学医療系, 准教授 (80708595)
山上 優紀  奈良県立医科大学, 医学部, 助教 (90823956)
吉川 匡宣  奈良県立医科大学, 医学部附属病院, 研究員 (20632764)
Project Period (FY) 2019-04-01 – 2024-03-31
Project Status Completed (Fiscal Year 2023)
Budget Amount *help
¥17,030,000 (Direct Cost: ¥13,100,000、Indirect Cost: ¥3,930,000)
Fiscal Year 2023: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2022: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2021: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2020: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2019: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Keywords光曝露 / 体内時計 / サーカディアンリズム / 糖尿病 / 動脈硬化 / うつ症状 / 睡眠 / 肥満 / うつ / アクチグラフ / メラトニン / がん / 認知機能 / 光害 / 睡眠障害 / 予後 / 寝室
Outline of Research at the Start

現代人はこれまでに人類が経験したことのない大量の夜間の人工光を浴びている。白熱電球の発明以来、人類の光消費量は増加の一途を辿っているが、近年の研究で不適切な光曝露が体内時計の乱れを引き起こし、睡眠だけでなく代謝・内分泌・循環器・精神機能・発がんなど様々な生理機能に影響を及ぼすことが分かってきた。これまでに光曝露の様々な健康影響が報告されているが、疾病発症など中長期の健康影響については未だ不明である。本課題研究で3000人に拡大したコホートを追跡調査し、光曝露が動脈硬化の進行や糖尿病・心血管疾患・がん・認知機能障害などの新規罹患および予後に及ぼす中長期影響を明らかにする。

Outline of Final Research Achievements

Modern people are exposed to a large amount of artificial light at night that humanity has never experienced before. Since the invention of the incandescent light bulb, human light consumption has been steadily increasing, but recent research has revealed that inappropriate light exposure can disrupt the body clock and affect not only sleep but also various physiological functions. In this study, we investigated the light environment of more than 3,000 local residents and clarified the effects on the onset of diabetes and the progression of arteriosclerosis.

Academic Significance and Societal Importance of the Research Achievements

人類は経験したことのない大量の夜間の人工光を浴びているが、その健康影響をリアルワールドデータを用いて調査した研究は乏しい。本研究では3000人を超える地域住民の光環境を調査し健康影響を明らかにした。今後、人類がどのように光を浴びていくべきか、どのような技術革新が必要か、など多くの問題が提起されるものと思われる。

Report

(6 results)
  • 2023 Annual Research Report   Final Research Report ( PDF )
  • 2022 Annual Research Report
  • 2021 Annual Research Report
  • 2020 Annual Research Report
  • 2019 Annual Research Report
  • Research Products

    (98 results)

All 2024 2023 2022 2021 2020 2019 2018 Other

All Journal Article (36 results) (of which Peer Reviewed: 36 results,  Open Access: 13 results) Presentation (51 results) (of which Int'l Joint Research: 6 results,  Invited: 8 results) Book (7 results) Remarks (3 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] Effects of Violet-Excitation Light-Emitting Diode on Melatonin Secretion and Sleepiness: Preliminary Findings from A Randomized Controlled Trial2024

    • Author(s)
      Mitsui K, Saeki K, Sun M, Yamagami Y, Tai Y, Obayashi K.
    • Journal Title

      J Clin Sleep Med

      Volume: Jan 1;20(1) Issue: 1 Pages: 101-109

    • DOI

      10.5664/jcsm.10814

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Blood pressure, pulse rate, and skin temperature during hot-water bathing in real-world settings among community-dwelling older adults: the HEIJO-KYO Study2024

    • Author(s)
      Tai Y, Obayashi K, Okumura K, Yamagami Y, Saeki K.
    • Journal Title

      Environmental Health and Preventive Medicine

      Volume: 29 Issue: 0 Pages: 12-12

    • DOI

      10.1265/ehpm.23-00320

    • ISSN
      1342-078X, 1347-4715
    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Daily Light Exposure Profiles and the Association with Objective Sleep Quality in Patients with Parkinson’s Disease: The PHASE Study2024

    • Author(s)
      Obayashi K, Saeki K, Tai Y, Yamagami Y, Esaki Y, Yoshikawa T, Sugie K, Kataoka H.
    • Journal Title

      Sleep

      Volume: 2024 Issue: 8

    • DOI

      10.1093/sleep/zsae036

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Association Between Before-bedtime Passive Body Heating and Nocturia During the Cold Season Among Older Adults2023

    • Author(s)
      Tai Yoshiaki、Obayashi Kenji、Okumura Kazuki、Yamagami Yuki、Negoro Hiromitsu、Kurumatani Norio、Saeki Keigo
    • Journal Title

      Journal of Epidemiology

      Volume: 33 Issue: 8 Pages: 398-404

    • DOI

      10.2188/jea.JE20210471

    • NAID

      130008161541

    • ISSN
      0917-5040, 1349-9092
    • Year and Date
      2023-08-05
    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Association between indoor noise level at night and objective/subjective sleep quality in the older population: A cross-sectional study of the HEIJO-KYO cohort2023

    • Author(s)
      Yamagami Y, Obayashi K, Tai Y, Saeki K.
    • Journal Title

      SLEEP

      Volume: 10;46(5) Issue: 5 Pages: 197-197

    • DOI

      10.1093/sleep/zsac197

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Circadian blood pressure variability and asymmetric dimethylarginine in patients with glaucoma: cross-sectional study of The LIGHT cohort2023

    • Author(s)
      Yoshikawa Tadanobu、Obayashi Kenji、Miyata Kimie、Jimura Hironobu、Saeki Keigo、Ogata Nahoko
    • Journal Title

      Journal of Hypertension

      Volume: 41 Issue: 6 Pages: 1018-1023

    • DOI

      10.1097/hjh.0000000000003429

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Association between circadian skin temperature rhythms and actigraphic sleep measures in real-life settings2023

    • Author(s)
      Tai Yoshiaki、Obayashi Kenji、Yamagami Yuki、Saeki Keigo
    • Journal Title

      Journal of Clinical Sleep Medicine

      Volume: 19 Issue: 7 Pages: 1281-1292

    • DOI

      10.5664/jcsm.10590

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Circadian Variability of Objective Sleep Measures Predicts the Relapse of a Mood Episode in Bipolar Disorder: Findings from the APPLE Cohort2023

    • Author(s)
      江崎悠一, 大林賢史, 佐伯圭吾, 藤田潔, 岩田仲生, 北島剛司
    • Journal Title

      Psychiat Clin Neuros

      Volume: 77 Issue: 8 Pages: 442-448

    • DOI

      10.1111/pcn.13556

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Positive Association between Macular Pigment Optical Density and Glomerular Filtration Rate: A Cross-Sectional Study2023

    • Author(s)
      辻中大生, 佐伯圭吾, 大林賢史, 西智, 上田哲生, 緒方奈保子
    • Journal Title

      J Clin Med

      Volume: 12 Issue: 16 Pages: 5312-5312

    • DOI

      10.3390/jcm12165312

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Post-Illumination Pupil Response and Sleep Quality in Patients With Glaucoma: The LIGHT Study2023

    • Author(s)
      Jimura Hironobu、Yoshikawa Tadanobu、Obayashi Kenji、Miyata Kimie、Saeki Keigo、Ogata Nahoko
    • Journal Title

      Investigative Opthalmology & Visual Science

      Volume: 64 Issue: 12 Pages: 34-34

    • DOI

      10.1167/iovs.64.12.34

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Habitual Light Exposure and Circadian Activity Rhythm in Bipolar Disorder: A Cross-Sectional Analysis of the APPLE Cohort2023

    • Author(s)
      江崎悠一, 大林賢史, 佐伯圭吾, 藤田潔, 岩田仲生, 北島剛司
    • Journal Title

      J Affect Disord

      Volume: 323 Pages: 762-769

    • DOI

      10.1016/j.jad.2022.12.034

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Breakfast Skipping and Declines in Cognitive Score among Community-Dwelling Older Adults: A Longitudinal Study of the HEIJO-KYO Cohort2022

    • Author(s)
      Ishizuka R, Otaki N, Tai Y, Yamagami Y, Tanaka K, Morikawa M, Iki M, Kurumatani N, Saeki K, Obayashi K.
    • Journal Title

      J Geriatr Psychiatry Neurol.

      Volume: 8919887221135551 Issue: 4 Pages: 316-322

    • DOI

      10.1177/08919887221135551

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Associations between indoor light pollution and unhealthy outcomes in 2,947 adults: cross-sectional analysis in the HEIJO-KYO cohort2022

    • Author(s)
      Obayashi K, Tai Y, Yamagami Y, Saeki K.
    • Journal Title

      Environ Res.

      Volume: 215 Pages: 114350-114350

    • DOI

      10.1016/j.envres.2022.114350

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Influence of Depression on the Association between Colder Indoor Temperature and Higher Blood Pressure2022

    • Author(s)
      Okumura K, Obayashi K, Tai Y, Yamagami Y, Kurumatani N, Saeki K.
    • Journal Title

      Journal of Hypertensions

      Volume: 40(10) Issue: 10 Pages: 2013-2021

    • DOI

      10.1097/hjh.0000000000003221

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Inverse Association of Skin Temperature With Ambulatory Blood Pressure and the Mediation of Skin Temperature in Blood Pressure Responses to Ambient Temperature2022

    • Author(s)
      Tai Y, Obayashi K, Yamagami Y, Saeki K
    • Journal Title

      Hypertension

      Volume: - Issue: 8 Pages: 1845-1855

    • DOI

      10.1161/hypertensionaha.122.19190

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Short-wavelength light exposure at night and sleep disturbances accompanied by decreased melatonin secretion in real-life settings: a cross-sectional study of the HEIJO-KYO cohort2022

    • Author(s)
      Mitsui Katsuhiro、Saeki Keigo、Tone Nobuhiro、Suzuki Shinji、Takamiya Syoichi、Tai Yoshiaki、Yamagami Yuki、Obayashi Kenji
    • Journal Title

      Sleep Medicine

      Volume: 90 Pages: 192-198

    • DOI

      10.1016/j.sleep.2022.01.023

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Comparison of objective and subjective sleep parameters in patients with bipolar disorder in both euthymic and residual symptomatic periods2022

    • Author(s)
      Fujita Akari、Esaki Yuichi、Obayashi Kenji、Saeki Keigo、Fujita Kiyoshi、Iwata Nakao、Kitajima Tsuyoshi
    • Journal Title

      Journal of Psychiatric Research

      Volume: 145 Pages: 190-196

    • DOI

      10.1016/j.jpsychires.2021.12.015

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Association Between Passive Body Heating by Hot Water Bathing Before Bedtime and Depressive Symptoms Among Community-Dwelling Older Adults2022

    • Author(s)
      Tai Yoshiaki、Obayashi Kenji、Yamagami Yuki、Kurumatani Norio、Saeki Keigo
    • Journal Title

      The American Journal of Geriatric Psychiatry

      Volume: 30 Issue: 2 Pages: 161-170

    • DOI

      10.1016/j.jagp.2021.06.010

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Circadian Activity Rhythm in Parkinson's Disease: Findings from the PHASE Study2021

    • Author(s)
      大林賢史, 佐伯圭吾, 山上優紀, 車谷典男, 杉江和馬, 形岡博史
    • Journal Title

      Sleep Med

      Volume: 85 Pages: 8-14

    • DOI

      10.1016/j.sleep.2021.06.023

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Preventive effect of morning light exposure on relapse into depressive episode in bipolar disorder2021

    • Author(s)
      Esaki Yuichi、Obayashi Kenji、Saeki Keigo、Fujita Kiyoshi、Iwata Nakao、Kitajima Tsuyoshi
    • Journal Title

      Acta Psychiatrica Scandinavica

      Volume: 143 Issue: 4 Pages: 328-338

    • DOI

      10.1111/acps.13287

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Association Between the Asymmetric Dimethylarginine Levels and Glaucoma Severity: A Cross-Sectional Analysis of the LIGHT Study2021

    • Author(s)
      Yoshikawa Tadanobu、Obayashi Kenji、Miyata Kimie、Saeki Keigo、Ogata Nahoko
    • Journal Title

      Investigative Opthalmology & Visual Science

      Volume: 62 Issue: 4 Pages: 7-7

    • DOI

      10.1167/iovs.62.4.7

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Hot water bathing before bedtime and shorter sleep onset latency is accompanied by a higher distal-proximal skin temperature gradient in older adults2021

    • Author(s)
      Tai Y, Obayashi K, Yamagami Y, Yoshimoto K, Kurumatani N, Nishio K, Saeki K.
    • Journal Title

      J Clin Sleep Med

      Volume: Epub ahead of print Issue: 6 Pages: 1257-1266

    • DOI

      10.5664/jcsm.9180

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Lower Cognitive Function in Patients With Functionally and Structurally Severe Glaucoma: The LIGHT Study2021

    • Author(s)
      Yoshikawa Tadanobu、Obayashi Kenji、Miyata Kimie、Saeki Keigo、Ogata Nahoko
    • Journal Title

      Journal of Glaucoma

      Volume: 30 Issue: 10 Pages: 882-886

    • DOI

      10.1097/ijg.0000000000001923

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Comparison of Objective and Subjective Sleep Parameters in Patients with Bipolar Disorder in Both Euthymic and Residual Symptomatic Periods2021

    • Author(s)
      藤田明里, 江崎悠一, 大林賢史, 佐伯圭吾, 藤田潔, 岩田仲生, 北島剛司
    • Journal Title

      J Psychiatr Res

      Volume: 145 Issue: 1 Pages: 190-196

    • DOI

      10.1038/s41398-021-01652-9

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Melatonin secretion in patients with Parkinson's disease receiving different-dose levodopa therapy2020

    • Author(s)
      Kataoka H, Saeki K, Kurumatani N, Sugie K, Obayashi K.
    • Journal Title

      Sleep Med.

      Volume: 75 Pages: 309-314

    • DOI

      10.1016/j.sleep.2020.07.043

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Higher prevalence of intentional self-harm in bipolar disorder with evening chronotype: A finding from the APPLE cohort study2020

    • Author(s)
      Esaki Yuichi、Obayashi Kenji、Saeki Keigo、Fujita Kiyoshi、Iwata Nakao、Kitajima Tsuyoshi
    • Journal Title

      Journal of Affective Disorders

      Volume: 277 Pages: 727-732

    • DOI

      10.1016/j.jad.2020.08.068

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Decreased melatonin secretion in patients with glaucoma: quantitative association with glaucoma severity in the LIGHT study2020

    • Author(s)
      Yoshikawa Tadanobu、Obayashi Kenji、Miyata Kimie、Saeki Keigo、Ogata Nahoko
    • Journal Title

      Journal of Pineal Research

      Volume: in press Issue: 2

    • DOI

      10.1111/jpi.12662

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Association between light exposure at night and manic symptoms in bipolar disorder: cross-sectional analysis of the APPLE cohort2020

    • Author(s)
      Esaki Y, Obayashi K, Saeki K, Fujita K, Iwata N, Kitajima T.
    • Journal Title

      Chronobiol Int.

      Volume: 37 Pages: 887-896

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of Cataract Surgery on Melatonin Secretion in Adults 60 Years and Older2020

    • Author(s)
      Nishi Tomo、Saeki Keigo、Miyata Kimie、Yoshikawa Tadanobu、Ueda Tetsuo、Kurumatani Norio、Obayashi Kenji、Ogata Nahoko
    • Journal Title

      JAMA Ophthalmology

      Volume: 138 Issue: 4 Pages: 405-405

    • DOI

      10.1001/jamaophthalmol.2020.0206

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Objective sleep measures between patients with Parkinson's disease and community-based older adults2020

    • Author(s)
      Kataoka H, Saeki K, Kurumatani N, Sugie K, Obayashi K.
    • Journal Title

      Sleep Med.

      Volume: 68 Pages: 110-114

    • DOI

      10.1016/j.sleep.2019.09.010

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Objectively  measured physical activity relates to night-time blood pressure in older adults: cross-sectional analysis in the HEIJO-KYO cohort.2020

    • Author(s)
      Yamagami Y, Saeki K, Tai Y, Maegawa T, Iwamoto J, Kataoka H, et al.
    • Journal Title

      J Hypertens.

      Volume: 38(4) Issue: 4 Pages: 649-55

    • DOI

      10.1097/hjh.0000000000002302

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Bedroom lighting environment  and  incident diabetes mellitus: a longitudinal study of the HEIJO-KYO cohort2020

    • Author(s)
      Obayashi K, Yamagami Y, Kurumatani N, Saeki K
    • Journal Title

      Sleep medicine

      Volume: 65 Pages: 1-3

    • DOI

      10.1016/j.sleep.2019.07.006

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Cataracts and Subclinical Carotid Atherosclerosis in Older Adults ― A Cross-Sectional Study of the HEIJO-KYO Cohort ―2019

    • Author(s)
      Yoshikawa Tadanobu、Obayashi Kenji、Miyata Kimie、Nishi Tomo、Ueda Tetsuo、Kurumatani Norio、Saeki Keigo、Ogata Nahoko
    • Journal Title

      Circulation Journal

      Volume: 83 Issue: 10 Pages: 2044-2048

    • DOI

      10.1253/circj.CJ-19-0118

    • NAID

      130007711603

    • ISSN
      1346-9843, 1347-4820
    • Year and Date
      2019-09-25
    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Indoor light pollution  and progression of carotid atherosclerosis: A longitudinal study of the HEIJO-KYO cohort2019

    • Author(s)
      Obayashi K, Yamagami Y, Tatsumi S, Kurumatani N, Saeki K
    • Journal Title

      Environ Int.

      Volume: 133(Pt B) Pages: 105184-105184

    • DOI

      10.1016/j.envint.2019.105184

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Association between timing of hot water bathing before bedtime and night-/sleep-time blood pressure and dipping in the elderly: a longitudinal analysis for repeated measurements in home settings2019

    • Author(s)
      Tai Yoshiaki、Saeki Keigo、Yamagami Yuki、Yoshimoto Kiyomi、Kurumatani Norio、Nishio Kenji、Obayashi Kenji
    • Journal Title

      Chronobiology International

      Volume: 36 Issue: 12 Pages: 1714-1722

    • DOI

      10.1080/07420528.2019.1675685

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Association between glaucomatous optic disc and depressive symptoms independent of light exposure profiles: a cross-sectional study of the HEIJO-KYO cohort2018

    • Author(s)
      Yoshikawa Tadanobu、Obayashi Kenji、Miyata Kimie、Ueda Tetsuo、Kurumatani Norio、Saeki Keigo、Ogata Nahoko
    • Journal Title

      British Journal of Ophthalmology

      Volume: 印刷中 Issue: 8 Pages: 1119-1122

    • DOI

      10.1136/bjophthalmol-2018-312176

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Presentation] 奈良県における心房細動の有病割合と危険因子に関する特定健診データを用いた横断研究2024

    • Author(s)
      浅井祐志, 尾上健児, 周藤俊治, 和家佐日登美, 大林賢史, 石原里美, 中田康紀, 橋本行弘, 中川仁, 上田友哉, 妹尾絢子, 西田卓, 中井健仁, 渡邉真言, 佐伯圭吾, 彦惣俊吾
    • Organizer
      日本疫学会学術総会
    • Related Report
      2023 Annual Research Report
  • [Presentation] 体内時計の乱れと睡眠障害-問題解決のカギは上手な光の浴び方ー2024

    • Author(s)
      大林賢史
    • Organizer
      けいはんなサイエンスカフェ(セミナー講演)
    • Related Report
      2023 Annual Research Report
    • Invited
  • [Presentation] Analysis of Prevalence of Atrial Fibrillation Using Annual Health Checkups Data in Nara Prefecture2024

    • Author(s)
      浅井祐志, 尾上健児, 周藤俊治, 和家佐日登美, 大林賢史, 中井健仁, 彦惣俊吾, 佐伯圭吾
    • Organizer
      日本循環器学会学術集会
    • Related Report
      2023 Annual Research Report
  • [Presentation] 緑内障患者における内因性光感受性網膜神経節細胞の機能と睡眠の質の関連2023

    • Author(s)
      治村寛信, 吉川匡宣, 大林賢史, 宮田季美恵, 佐伯圭吾, 緒方奈保子
    • Organizer
      日本眼科学会総会
    • Related Report
      2023 Annual Research Report
  • [Presentation] Effect of Nighttime Bedroom Light Exposure on Mood Episode Relapses in Bipolar disorder: Results from A Prospective Cohort Study2023

    • Author(s)
      江崎悠一, 大林賢史, 佐伯圭吾, 藤田潔, 岩田仲生, 北島剛
    • Organizer
      Annual Conference of the International Society for Bipolar Disorders
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 緑内障患者における視神経乳頭血流障害と内因性光感受性網膜神経節細胞機能の関連2023

    • Author(s)
      治村寛信, 吉川匡宣, 大林賢史, 宮田季美恵, 佐伯圭吾, 緒方奈保子
    • Organizer
      日本眼循環学会
    • Related Report
      2023 Annual Research Report
  • [Presentation] 有機EL(OLED)照明とLED照明が眠気に及ぼす影響-無作為化クロスオーバー試験-2023

    • Author(s)
      澤木友利華, 久保智樹, 山口洋一, 山上優紀, 佐伯圭吾, 大林賢史
    • Organizer
      照明学会全国大会
    • Related Report
      2023 Annual Research Report
  • [Presentation] 不適切な光曝露が引き起こす心血管代謝疾患2023

    • Author(s)
      大林賢史
    • Organizer
      日本睡眠学会定期学術集会
    • Related Report
      2023 Annual Research Report
    • Invited
  • [Presentation] 内因性メラトニンの抗動脈硬化作用2023

    • Author(s)
      大林賢史
    • Organizer
      日本睡眠学会定期学術集会
    • Related Report
      2023 Annual Research Report
    • Invited
  • [Presentation] 双極性障害における日常生活光曝露と概日活動リズムとの横断的関連:APPLEコホー トスタディからの知見2023

    • Author(s)
      江崎悠一, 大林賢史, 佐伯圭吾, 藤田潔, 岩田仲生, 北島剛司
    • Organizer
      日本睡眠学会定期学術集会
    • Related Report
      2023 Annual Research Report
  • [Presentation] 有機EL(OLED)照明とLED照明がメラトニン分泌に及ぼす影響 ―無作為化クロスオーバー試験―2023

    • Author(s)
      澤木友利華, 久保智樹, 山口洋一, 山上優紀, 佐伯圭吾, 大林賢史
    • Organizer
      日本睡眠学会定期学術集会
    • Related Report
      2023 Annual Research Report
  • [Presentation] パーキンソン病における就寝時末梢皮膚温と客観的睡眠指標の関連:PHASEスタディ2023

    • Author(s)
      田井義彬, 大林賢史, 山上優紀, 佐伯圭吾, 杉江和馬, 形岡博史
    • Organizer
      日本睡眠学会定期学術集会
    • Related Report
      2023 Annual Research Report
  • [Presentation] 就寝中の寝室温高値と客観的睡眠指標悪化の関連2023

    • Author(s)
      奥村和生, 大林賢史, 田井義彬, 山上優紀, 佐伯圭吾
    • Organizer
      日本睡眠学会学術集会
    • Related Report
      2023 Annual Research Report
  • [Presentation] パーキンソン病患者の光曝露量と客観的睡眠指標の関連:PHASEスタディ2023

    • Author(s)
      大林賢史, 佐伯圭吾, 田井義彬, 山上優紀, 杉江和馬, 形岡博史
    • Organizer
      日本睡眠学会学術集会
    • Related Report
      2023 Annual Research Report
  • [Presentation] 光環境と生活習慣病:最新の医学知見2023

    • Author(s)
      大林賢史
    • Organizer
      健康保険組合連合会大阪連合会(セミナー講演)
    • Related Report
      2023 Annual Research Report
    • Invited
  • [Presentation] 長時間の夜間空腹と低い骨格筋量との関連2023

    • Author(s)
      大滝直人, 田井義彬, 山上優紀, 大林 賢史, 佐伯圭吾
    • Organizer
      日本栄養・食糧学会近畿支部大会
    • Related Report
      2023 Annual Research Report
  • [Presentation] 光環境が健康に及ぼす影響:現状のエビデンスと今後の課題2023

    • Author(s)
      大林賢史
    • Organizer
      日本衛生学会学術総会
    • Related Report
      2022 Annual Research Report
    • Invited
  • [Presentation] 実生活環境下の入浴と夜間頻尿の短期縦断的関連:平城京スタディ2023

    • Author(s)
      田井義彬, 大林賢史, 山上優紀, 佐伯圭吾
    • Organizer
      日本疫学会学術総会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 有機EL(OLED)照明とLED照明が夜間作業効率と眠気に及ぼす影響-無作為化クロスオーバー非劣性試験-2022

    • Author(s)
      澤木友利華, 久保智樹, 山口洋一, 清水宏司, 山上優紀, 佐伯圭吾, 大林賢史
    • Organizer
      室内環境学会学術集会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 紫色励起LEDのメラトニン分泌、客観的覚醒度、主観的眠気への影響: 無作為化クロスオーバー試験2022

    • Author(s)
      三井勝裕, 佐伯圭吾, 孫明ゆえ, 山上優紀, 田井義彬, 大林賢史
    • Organizer
      日本時間生物学会学術大会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 皮膚温リズムと肥満の関連:平城京スタディ2022

    • Author(s)
      田井義彬, 大林賢史, 山上優紀, 佐伯圭吾
    • Organizer
      日本時間生物学会学術大会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 黄斑色素密度と腎糸球体濾過量の関連2022

    • Author(s)
      辻中大生, 佐伯圭吾, 大林賢史, 西智, 上田哲生, 緒方奈保子
    • Organizer
      日本網膜硝子体学会総会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 総死亡の相対危険が最低となる室温の推計:既存データとコホートデータを用いた分析2022

    • Author(s)
      佐伯圭吾, 田井義彬, 山上優紀, 大林賢史
    • Organizer
      日本公衆衛生学会総会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 実生活環境下における寒冷曝露時の血圧上昇における皮膚温の媒介効果:平城京スタディ2022

    • Author(s)
      田井義彬, 大林賢史, 山上優紀, 佐伯圭吾
    • Organizer
      日本公衆衛生学会総会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 冬の室内寒冷曝露と筋力・歩行速度低値の横断関連: 平城京スタディ2022

    • Author(s)
      諏訪内宏益, 大林賢史, 田井義彬, 山上優紀, 佐伯圭吾
    • Organizer
      日本公衆衛生学会総会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 緑内障患者における内因性光感受性網膜神経節細胞障害と認知機能の関連2022

    • Author(s)
      吉川匡宣, 大林賢史, 宮田季美恵, 治村寛信, 佐伯圭吾, 緒方奈保子
    • Organizer
      日本緑内障学会学術集会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 睡眠休養感に影響しうる生活環境要因2022

    • Author(s)
      佐伯圭吾, 大林賢史
    • Organizer
      日本睡眠学会定期学術集会
    • Related Report
      2022 Annual Research Report
    • Invited
  • [Presentation] 実生活環境下での入浴と客観的睡眠指標の縦断的関連:外気温による効果修飾(平城京スタディ)2022

    • Author(s)
      田井義彬, 大林賢史, 山上優紀, 佐伯圭吾
    • Organizer
      日本睡眠学会学術集会
    • Related Report
      2022 Annual Research Report
  • [Presentation] うつ症状の有無が寒冷曝露と血圧高値の関連に及ぼす影響:平城京スタディ2022

    • Author(s)
      奥村和生, 大林賢史, 田井義彬, 山上優紀, 佐伯圭吾
    • Organizer
      日本精神神経学会学術総会
    • Related Report
      2022 Annual Research Report
  • [Presentation] Association between Circadian Activity Rhythms and Mood Episode Relapse in Bipolar disorder: Results from A Prospective Cohort Study2022

    • Author(s)
      江崎悠一, 大林賢史, 佐伯圭吾, 藤田潔, 岩田仲生, 北島剛
    • Organizer
      Anual Conference of the International Conference of Psychiatry and Neurosciences
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 寛解期および病相期を含めた双極性障害患者における客観的・主観的睡眠パラメータの比較2022

    • Author(s)
      藤田明里, 江崎悠一, 大林賢史, 佐伯圭吾, 藤田潔, 岩田仲生, 北島剛司
    • Organizer
      日本精神神経学会学術総会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 内因性光感受性網膜神経節細胞機能と緑内障重症度の関連:LIGHTスタディ2022

    • Author(s)
      宮田季美恵, 吉川匡宣, 大林賢史, 治村寛信, 佐伯圭吾, 緒方奈保子
    • Organizer
      日本眼科学会総会
    • Related Report
      2022 Annual Research Report
  • [Presentation] Preventive Effect of Morning Light Exposure on Relapse of Depressive Episode in Bipolar Disorder: Results from A Prospective Cohort Study2021

    • Author(s)
      江崎悠一, 大林賢史, 佐伯圭吾, 藤田潔, 岩田仲生, 北島剛司
    • Organizer
      Annual Conference of the International Society for Bipolar Disorders
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 双極性障害患者における夜型クロノタイプと自傷行為との横断的関連:APPLEコホー トスタディからの知見2021

    • Author(s)
      江崎悠一, 大林賢史, 佐伯圭吾, 藤田潔, 岩田仲生, 北島剛司
    • Organizer
      日本睡眠学会学術集会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 高齢者における夜間頻尿と入浴との関連:平城京スタディ2021

    • Author(s)
      田井義彬, 大林賢史, 山上優紀, 車谷典男, 佐伯圭吾
    • Organizer
      日本睡眠学会学術集会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 緑内障患者におけるADMAと夜間血圧の関連: LIGHTスタディ2021

    • Author(s)
      吉川匡宣, 大林賢史, 宮田季美恵, 佐伯圭吾, 緒方奈保子
    • Organizer
      日本眼循環学会学術集会
    • Related Report
      2021 Annual Research Report
  • [Presentation] Effect of Evening Light Exposure on Sleep in Bipolar Disorder: A Longitudinal Analysis for Repeated Measures in the APPLE Cohort2021

    • Author(s)
      江崎悠一, 大林賢史, 佐伯圭吾, 藤田潔, 岩田仲生, 北島剛司
    • Organizer
      Annual Conference of the International Society for Affective Disorders
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Association between Circadian Characteristics of the Distal Skin Temperature Rhythm and Actigraphic Sleep in Community-Dwelling Older Adults2021

    • Author(s)
      田井義彬, 大林賢史, 山上優紀, 佐伯圭吾
    • Organizer
      日本時間生物学会学術大会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 実生活の入浴中の血圧変動と皮膚温の関連:1527人の大規模疫学研究(平城京スタディ)2021

    • Author(s)
      田井義彬, 大林賢史, 山上優紀, 佐伯圭吾
    • Organizer
      日本公衆衛生学会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 夜間排尿回数と夜間光曝露との関連:平城京スタディ2020

    • Author(s)
      三井勝裕, 佐伯圭吾, 刀根庸浩, 鈴木信二, 高宮祥一, 田井義彬, 山上優紀, 大林賢史
    • Organizer
      日本時間生物学会学術大会
    • Related Report
      2020 Annual Research Report
  • [Presentation] 光環境と健康に関する最新の医学エビデンス2020

    • Author(s)
      大林賢史
    • Organizer
      経産省地域企業イノベーション支援事業プロジェクト All Japan Lighting Laboratory(セミナー講演)
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] 高齢者の朝食欠食と認知機能低下の関連:平城京コホート縦断分析2020

    • Author(s)
      石塚理香, 大滝直人, 田井義彬, 山上優紀, 田中邦彦, 森川将行, 伊木雅之, 車谷典男, 佐伯圭吾, 大林賢史
    • Organizer
      日本栄養改善学会学術総会
    • Related Report
      2020 Annual Research Report
  • [Presentation] 日常生活における日中光曝露と双極性障害のうつ症状との関連:APPLE コホートスタディからの横断解析2020

    • Author(s)
      江﨑悠一, 大林賢史, 佐伯圭吾, 藤田潔, 岩田仲生, 北島剛司
    • Organizer
      日本精神神経学会学術総会
    • Related Report
      2020 Annual Research Report
  • [Presentation] 室内光環境の健康影響:最新の医学エビデンス2019

    • Author(s)
      大林賢史
    • Organizer
      日本インテリア健康学協会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Sleep Disturbances in Older Adults Exposed to Short-Wavelength Light at Night: the HEIJO-KYO Cohort2019

    • Author(s)
      三井勝裕, 佐伯圭吾, 刀根庸浩, 鈴木信二, 高宮祥一, 山上優紀, 車谷典男, 大林賢史
    • Organizer
      日本時間生物学会学術大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Nighttime Light Exposure and the Incidence of Diabetes Mellitus: A Longitudinal Study of the HEIJO-KYO Cohort2019

    • Author(s)
      大林賢史, 山上優紀, 車谷典男, 佐伯圭吾
    • Organizer
      World Sleep
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 白内障と動脈硬化進行の関連:平城京スタディ縦断解析2019

    • Author(s)
      吉川匡宣, 大林賢史, 宮田季美恵, 佐伯圭吾, 緒方奈保子
    • Organizer
      日本白内障学会総会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 夜間光曝露と糖尿病発症の関連:平城京スタディ縦断分析2019

    • Author(s)
      大林賢史, 山上優紀, 巽志伸, 車谷典男, 佐伯圭吾
    • Organizer
      日本睡眠学会定期学術集会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Lower Melatonin Secretion in Elderly Individuals Exposed to Nighttime Short-Wavelength Light at Eye-Level2019

    • Author(s)
      三井勝裕, 佐伯圭吾, 刀根庸浩, 鈴木信二, 高宮祥一, 山上優紀, 大林賢史
    • Organizer
      日本睡眠学会定期学術集会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Glaucomatous Optic Disc and Changes in Sleep Quality in Elderly Individuals: the HEIJO-KYO Cohort2019

    • Author(s)
      宮田季美恵, 大林賢史, 吉川匡宣, 山上優紀, 上田哲生, 車谷典男, 佐伯圭吾, 緒方奈保子
    • Organizer
      日本睡眠学会定期学術集会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Effect of Bathing on Nighttime Blood Pressure among Elderly: Longitudinal Analysis of Repeated Measurements in the HEIJO-KYO Cohort2019

    • Author(s)
      田井義彬, 大林賢史, 吉本清己, 西尾健治, 佐伯圭吾
    • Organizer
      WONCA Asia Pacific Region Conference
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Book] 室内環境の事典:快適で健康な暮らしを支える科学2023

    • Author(s)
      大林賢史
    • Total Pages
      2
    • Publisher
      朝倉書店
    • ISBN
      4254266529
    • Related Report
      2023 Annual Research Report
  • [Book] 睡眠医療2023

    • Author(s)
      大林賢史
    • Total Pages
      4
    • Publisher
      ライフ・サイエンス
    • ISBN
      4898017886
    • Related Report
      2023 Annual Research Report
  • [Book] メディカルビューポイント2022

    • Author(s)
      大林賢史
    • Total Pages
      2
    • Publisher
      医事出版社
    • Related Report
      2021 Annual Research Report
  • [Book] 最新臨床睡眠学-睡眠障害の基礎と臨床-(日本臨床 2020年12月増刊号)2020

    • Author(s)
      大林賢史
    • Total Pages
      5
    • Publisher
      日本臨床社
    • Related Report
      2020 Annual Research Report
  • [Book] 日本臨床 2020年5月号(Vol.78 No.5)2020

    • Author(s)
      大林賢史
    • Total Pages
      5
    • Publisher
      日本臨床社
    • Related Report
      2020 Annual Research Report
  • [Book] 住まいとでんき 2020年5月号(Vol.32 No.5)2020

    • Author(s)
      大林賢史
    • Total Pages
      4
    • Publisher
      日本工業出版株式会社
    • Related Report
      2020 Annual Research Report
  • [Book] Indoor Environmental Quality and Health Risk toward Healthier Environment for All2019

    • Author(s)
      佐伯圭吾, 大林賢史
    • Total Pages
      14
    • Publisher
      Springer
    • ISBN
      9813291818
    • Related Report
      2019 Annual Research Report
  • [Remarks] Researchmap

    • URL

      https://researchmap.jp/obayashi_k/

    • Related Report
      2020 Annual Research Report 2019 Annual Research Report
  • [Remarks] 奈良県立医科大学 疫学・予防医学講座

    • URL

      https://www.naramed-u.ac.jp/~epi/index.html

    • Related Report
      2020 Annual Research Report
  • [Remarks] 奈良県立医科大学 疫学・予防医学講座

    • URL

      http://www.naramed-u.ac.jp/~epi/index.html

    • Related Report
      2019 Annual Research Report
  • [Patent(Industrial Property Rights)] 照明装置、照明システム及び照明制御方法2020

    • Inventor(s)
      三井勝裕, 大林 賢史, 加藤秀崇
    • Industrial Property Rights Holder
      三井勝裕, 大林 賢史, 加藤秀崇
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2020-026628
    • Filing Date
      2020
    • Related Report
      2020 Annual Research Report

URL: 

Published: 2019-04-18   Modified: 2025-01-30  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi