| Budget Amount *help |
¥17,550,000 (Direct Cost: ¥13,500,000、Indirect Cost: ¥4,050,000)
Fiscal Year 2021: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2020: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2019: ¥7,410,000 (Direct Cost: ¥5,700,000、Indirect Cost: ¥1,710,000)
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| Outline of Final Research Achievements |
A number of methods have been developed to assess asbestos contamination in construction materials using microscopy and X-ray diffraction. However, adaptation of these methods to high-throughput analysis has been difficult. Amplified luminescence proximity homogeneous assay (Alpha) technology relies on binding of two different beads to a target of interest. In case of the binding and the resulting proximity of the two beads, an energy transfer from one bead to the other takes place. This results in the production of a chemiluminescent signal. Here we developed two different beads that display asbestos binding proteins and demonstrated that this technology would be applicable to high-throughput analysis of asbestos.
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