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Eye gaze measurement in persons with ADHD and ASD using an eye tracker

Research Project

Project/Area Number 19K08055
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 52030:Psychiatry-related
Research InstitutionShowa University

Principal Investigator

Iwanami Akira  昭和大学, 医学部, 教授 (80276518)

Co-Investigator(Kenkyū-buntansha) 高塩 理  昭和大学, 医学部, 准教授 (00384256)
岡島 由佳  昭和大学, 医学部, 准教授 (50317525)
Project Period (FY) 2019-04-01 – 2022-03-31
Project Status Completed (Fiscal Year 2021)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2021: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2020: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2019: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
KeywordsADHD / ASD / アイトラッカー / 生物学的指標 / 視線計測 / ADOS / 表情認知 / 共同注意 / マインドワンダリング / 鑑別診断
Outline of Research at the Start

成人期の発達障害の代表的な疾患は、ADHD(注意欠如多動性障害)とASD(自閉症スペクトラム障害)であるが、この両者は精神症状においても、問題行動においても類似性が大きく鑑別困難なケースが多い。このため本研究においては、動画を視聴している際における被験者の視線をアイトラッカーを用いて計測し、両者を鑑別するための指標を求めるものである。過去の研究においては、ASDにおいては、動画の中の人の顔や目の部分を見ない傾向が指摘されている。本研究では対象者の精神症状を国際的な評価尺度によって評価し、視線計測との関連を検討する。

Outline of Final Research Achievements

We sought biological indicators that could differentiate between ADHD and ASD, the major developmental disorders of adulthood. It has been reported that persons with ASD look at people's faces less frequently in still or moving image tasks, and that they look at eyes less frequently among faces. In this study, eye tracking with an eye tracker was used to measure eye gaze in adult subjects with ADHD and ASD while they were watching a video task. The results showed that adults with ASD looked at people or eyes less frequently, while this was not the case with ADHD. The results suggest that gaze measurement may be used to differentiate between the two groups.

Academic Significance and Societal Importance of the Research Achievements

臨床的にADHDとASDはしばしば鑑別が困難である。特に成人のケースにおいては、両者の精神症状や問題行動が類似していることが多い。このため両者を鑑別可能な生物学的指標を明らかにすることにより、発達障害の診療はより充実したものになると考えられる。ADHDに対しては薬物療法が有効であるが、診断に至らないため、適切な治療が行われていないこともしばしばみられる。新たな生物学的指標を得ることにより、より適切な診療が可能になると考えられる。

Report

(4 results)
  • 2021 Annual Research Report   Final Research Report ( PDF )
  • 2020 Research-status Report
  • 2019 Research-status Report
  • Research Products

    (12 results)

All 2021 2020 2019

All Journal Article (6 results) (of which Peer Reviewed: 3 results,  Open Access: 3 results) Presentation (5 results) (of which Int'l Joint Research: 1 results) Book (1 results)

  • [Journal Article] Efficacy and safety of guanfacine extended-release in Japanese adults with attention-deficit/hyperactivity disorder: Exploratory post hoc subgroup analyses of a randomized, double-blind, placebo-controlled study2021

    • Author(s)
      Naya N, Sakai C, Okutsu D, Kiguchi R, Fujiwara M, Tsuji T, Iwanami A
    • Journal Title

      Neuropsychopharmacol Rep

      Volume: 41 Pages: 26-39

    • Related Report
      2021 Annual Research Report
  • [Journal Article] Similarity of subjective symptoms between autism spectrum disorder and attention-deficit/hyperactivity disorder in adults: Preliminary findings2021

    • Author(s)
      Nakagawa A, Hayashi W, Nishio T, Hanawa Y, Aoyagi K, Okajima Y, Iwanami A
    • Journal Title

      Neuropsychopharmacol Rep

      Volume: 41 Pages: 237-241

    • Related Report
      2021 Annual Research Report
  • [Journal Article] Correction to ASD symptoms in adults with ADHD: a preliminary study using the ADOS-22021

    • Author(s)
      Hayashi W, Hanawa Y, Iwami Y, Aoyagi K, Saga N, Nakamura D, Iwanami A
    • Journal Title

      Eur Arch Psychiatry Clin Neurosci

      Volume: ー Issue: 2 Pages: 233-233

    • DOI

      10.1007/s00406-021-01317-0

    • Related Report
      2021 Annual Research Report
  • [Journal Article] Spontaneous theory of mind in adults with attention-deficit/hyperactivity disorder2020

    • Author(s)
      Hayashi W, Arai G, Uno H, Saga N, Ikuse D, Takashio O, Iwanami A.
    • Journal Title

      Psychiatry Res

      Volume: 288 Pages: 113025-113025

    • DOI

      10.1016/j.psychres.2020.113025

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Efficacy and Safety of Guanfacine Extended-Release in the Treatment of Attention-Deficit/Hyperactivity Disorder in Adults: Results of a Randomized, Double-Blind, Placebo-Controlled Study2020

    • Author(s)
      Iwanami A, Saito K, Fujiwara M, Okutsu D, Ichikawa H
    • Journal Title

      J Clin Psychiatry

      Volume: 81 Issue: 3

    • DOI

      10.4088/jcp.19m12979

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Clinical Characteristics of Women with ADHD in Japan2019

    • Author(s)
      Hayashi W, Suzuki H, Saga N, Arai G, Igarashi R, Tokumasu T, Ota H, Yamada H, Takashio O, Iwanami A
    • Journal Title

      .Neuropsychiatr Dis Treat

      Volume: 15 Pages: 3367-3374

    • DOI

      10.2147/ndt.s232565

    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] ADHD専門プログラム改訂の取り組み2021

    • Author(s)
      水野健、横井英樹、五十嵐美紀、佐賀信之、中村暖、中村善文、岩波明
    • Organizer
      第2回日本成人期発達障害臨床医学会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 成人期ASDとADHDにおけるADOS-2の検討2021

    • Author(s)
      花輪洋一, 林若穂, 岩見有里子, 青柳啓介, 佐賀信之, 中村暖, 岩波明
    • Organizer
      第117回日本精神神経学会学術総会
    • Related Report
      2021 Annual Research Report
  • [Presentation] Overlap between ADHD and ASD symptoms in adulthood2021

    • Author(s)
      林若穂、花輪洋一、岩見有里子、岩波明
    • Organizer
      第2回日本成人期発達障害臨床医学会
    • Related Report
      2020 Research-status Report
  • [Presentation] 成人期ADHDにおけるSluggish Cognitive Tempoの検討2021

    • Author(s)
      岩見有里子、林若穂、花輪洋一、青柳啓介、佐賀信之、中村暖、岩波明
    • Organizer
      第2回日本成人期発達障害臨床医学会
    • Related Report
      2020 Research-status Report
  • [Presentation] Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study of Guanfacine Extended Release in Adults With Attention-Deficit/Hyperactivity Disorder2019

    • Author(s)
      Iwanami A, Saito K, Fujiwara M, et al.
    • Organizer
      The 7th World Congress on ADHD
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Book] 発達障害はなぜ誤診されるのか2021

    • Author(s)
      岩波明
    • Total Pages
      220
    • Publisher
      新潮社
    • ISBN
      9784106038631
    • Related Report
      2020 Research-status Report

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Published: 2019-04-18   Modified: 2023-01-30  

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