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Construction of an infectious disease epidemic prediction model by deep learning

Research Project

Project/Area Number 19K10614
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 58030:Hygiene and public health-related: excluding laboratory approach
Research InstitutionGunma University

Principal Investigator

Uchida Mitsuo  群馬大学, 大学院医学系研究科, 准教授 (00377251)

Project Period (FY) 2019-04-01 – 2022-03-31
Project Status Completed (Fiscal Year 2021)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2021: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2020: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2019: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords感染症 / AI / RNN / LSTM / 数理モデル / 流行予測 / Deep learning / 定点報告 / 全数報告 / 保健所 / AI / 地域
Outline of Research at the Start

本研究は,人工知能の技術のひとつである再帰型ニューラルネットワーク(RNN)の技術を用いて,県レベルの地方の感染症流行の予測をおこなうことを目的とした。群馬県の衛生環境研究所と連携して過去の感染症データを用いて流行予測モデルを作成し,研究開始後に実際報告される感染症の発生データを入力し,実際に精度の高い予測を行うことが可能かどうか検討する。

Outline of Final Research Achievements

The purpose of this study was to create a model to predict future epidemics of infectious diseases using AI technology with past epidemiological data. Data were collected at the Gunma Prefectural Institute of Public Health and Environment for the past 11 years from 2009 to 2019, including influenza, RS virus, pharyngoconjunctival fever, group A streptococcus, infectious gastroenteritis, varicella, hand-foot-and-mouth disease, erythema infectiosum, sudden rash, herpangina, epidemic mumps, epidemic keratitis conjunctivitis, and Mycoplasma. As a result of constructing a LSTM model, we were able to create a highly accurate prediction model for influenza and RS virus which were with enough cases.

Academic Significance and Societal Importance of the Research Achievements

本研究は,毎年周期的に流行を引き起こす感染症に対し,“その年の流行を予測できれば医療資源の準備や病床の確保を行うための参考情報にできるのではないか?”という発想の下で行われた。本研究の成果より,毎年多数報告されるインフルエンザやRSウイルスは予測精度の高いモデルを構築することができたが,他方,報告数の多くない感染症の予測精度は高くなかった。現在の学習型のAIは,学習のために多数のサンプル数を必要とするため,報告数の少ない感染症への対応に課題が残された。この課題は,今後の研究により解決することが望まれる。

Report

(4 results)
  • 2021 Annual Research Report   Final Research Report ( PDF )
  • 2020 Research-status Report
  • 2019 Research-status Report
  • Research Products

    (9 results)

All 2021 2020 2019

All Journal Article (6 results) (of which Peer Reviewed: 3 results,  Open Access: 3 results) Presentation (3 results) (of which Int'l Joint Research: 1 results)

  • [Journal Article] Changes in numbers of COVID-19 cases among residents of sightseeing resort areas before and during the “Go To Travel” campaign: Descriptive epidemiology in Gunma Prefecture2021

    • Author(s)
      Uchida Mitsuo
    • Journal Title

      Japanese Journal of Infectious Diseases

      Volume: advpub Issue: 0 Pages: 554-559

    • DOI

      10.7883/yoken.JJID.2021.122

    • NAID

      130008119521

    • ISSN
      1344-6304, 1884-2836
    • Year and Date
      2021-04-30
    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 社会医学研究におけるAIの活用例2021

    • Author(s)
      内田満夫,野下浩司,浅尾高行,小山洋
    • Journal Title

      BIO Clinica

      Volume: 36 Pages: 58-62

    • Related Report
      2021 Annual Research Report
  • [Journal Article] How has the COVID-19 Pandemic Affected Travelers and Tourist Destinations?2021

    • Author(s)
      Uchida Mitsuo
    • Journal Title

      Journal of Vaccines & Vaccination

      Volume: 12 Pages: 1-2

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 社会医学研究におけるAIの活用例2020

    • Author(s)
      内田満夫,野下浩司,浅尾高行,小山洋
    • Journal Title

      Precision Medicine

      Volume: 3 Pages: 74-78

    • Related Report
      2020 Research-status Report
  • [Journal Article] Effects of influenza vaccination on seasonal influenza symptoms: a prospective observational study in elementary schoolchildren in Japan2020

    • Author(s)
      Uchida M, Takeuchi S, Saito MM, Koyama H.
    • Journal Title

      Heliyon

      Volume: 6 Issue: 2 Pages: e03385-e03385

    • DOI

      10.1016/j.heliyon.2020.e03385

    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 社会医学領域において進めるAI研究2019

    • Author(s)
      内田満夫, 野下浩司, 浅尾高行, 小山 洋
    • Journal Title

      Precision Medicine

      Volume: 2 Pages: 72-76

    • NAID

      40022166967

    • Related Report
      2019 Research-status Report
  • [Presentation] 群馬県におけるCOVID-19に対する検査陽性率の推移に関する考察2021

    • Author(s)
      内田満夫
    • Organizer
      日本公衆衛生学会総会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 群馬県における新型コロナウイルス感染症の流行とその特徴2020

    • Author(s)
      内田満夫
    • Organizer
      日本公衆衛生学会総会
    • Related Report
      2020 Research-status Report
  • [Presentation] Estimation of infectious disease dynamics: Application of a recurrent neural network2019

    • Author(s)
      Uchida M.
    • Organizer
      American Public Health Association annual meeting
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research

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Published: 2019-04-18   Modified: 2023-01-30  

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