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Swallowing rehabilitation by peripheral magnetic stimulation of the suprahyoid muscles synchronized with swallowing reflex

Research Project

Project/Area Number 19K11311
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 59010:Rehabilitation science-related
Research InstitutionFujita Health University

Principal Investigator

Kagaya Hitoshi  藤田医科大学, 医学部, 教授 (40282181)

Co-Investigator(Kenkyū-buntansha) 青柳 陽一郎  日本医科大学, 大学院医学研究科, 大学院教授 (30286661)
稲本 陽子  藤田医科大学, 保健学研究科, 教授 (70612547)
Project Period (FY) 2019-04-01 – 2022-03-31
Project Status Completed (Fiscal Year 2021)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2021: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2020: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2019: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Keywords摂食嚥下障害 / 末梢磁気刺激 / 嚥下反射 / 舌骨上筋 / 舌骨下筋 / 磁気刺激
Outline of Research at the Start

高齢化社会に突入しているわが国において高齢者の摂食嚥下障害は重大な問題である.正常な嚥下では嚥下反射中に舌骨が挙上し,同時に食道入口部が開大することで食物が咽頭から食道へと送り込まれる.しかし,摂食嚥下障害患者では,舌骨の挙上が悪く,食道入口部もあまり開大しない.本研究では,嚥下反射の生じるタイミングに舌骨上筋に磁気刺激を行うことで,嚥下反射中の舌骨の挙上を増大させて,さらに食道入口部の開大も増加させる.経口摂取が不可能であった摂食嚥下障害患者に磁気刺激を行うことで経口摂取訓練が可能になれば,その意義は大きい.

Outline of Final Research Achievements

We synchronized the peripheral magnetic stimulation of the suprahyoid muscles with the swallowing reflex. The electromyography of the sternohyoid muscle during swallowing reflex was used as a trigger of the magnetic stimulation. The significant increases were observed in the anterior maximum movement distance of the hyoid bone and opening width of the upper oesophageal sphincter. In addition, we clarified the differences in muscle activities of the anterior belly of digastric, sternohyoid, masseter, temporal, and sternocleidomastoid muscles between discrete swallowing and chew-swallowing.

Academic Significance and Societal Importance of the Research Achievements

高齢者の摂食嚥下障害への対策は重要である.摂食嚥下障害では嚥下反射中の舌骨挙上が障害されることが多い.磁気刺激を用いて舌骨を疼痛なく挙上させることができ,嚥下反射と同期させることで,舌骨挙上,食道入口部開大をより大きくすることができた.摂食嚥下障害の新たな治療法の開発に目処がついた.また,1口嚥下と咀嚼嚥下という異なる嚥下様式における筋活動の違いを明らかにできたことで両者の生理的差異がより理解できるようになった.

Report

(4 results)
  • 2021 Annual Research Report   Final Research Report ( PDF )
  • 2020 Research-status Report
  • 2019 Research-status Report
  • Research Products

    (10 results)

All 2022 2021 2020 2019

All Journal Article (7 results) (of which Peer Reviewed: 4 results,  Open Access: 3 results) Presentation (3 results) (of which Int'l Joint Research: 1 results,  Invited: 2 results)

  • [Journal Article] Possible Rehabilitation Procedures to Treat Sarcopenic Dysphagia2022

    • Author(s)
      Kagaya Hitoshi、Inamoto Yoko
    • Journal Title

      Nutrients

      Volume: 14 Issue: 4 Pages: 778-778

    • DOI

      10.3390/nu14040778

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 一口嚥下と咀嚼嚥下における嚥下時の筋活動2021

    • Author(s)
      長島有毅
    • Journal Title

      日大歯学

      Volume: 95 Pages: 61-68

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 誤嚥性肺炎のリハビリテーション治療2021

    • Author(s)
      加賀谷 斉,戸田 芙美
    • Journal Title

      日本医師会雑誌

      Volume: 149 Pages: 2161-2164

    • Related Report
      2020 Research-status Report
  • [Journal Article] 【摂食嚥下障害に対する電気・磁気刺激療法】オーバービュー2020

    • Author(s)
      加賀谷 斉
    • Journal Title

      臨床リハ

      Volume: 29 Pages: 872-875

    • Related Report
      2020 Research-status Report
  • [Journal Article] 【摂食嚥下障害に対する電気・磁気刺激療法】末梢神経磁気刺激2020

    • Author(s)
      戸田 芙美,加賀谷 斉
    • Journal Title

      臨床リハ

      Volume: 29 Pages: 899-904

    • Related Report
      2020 Research-status Report
  • [Journal Article] The risk of laryngeal penetration or aspiration among discrete, sequential, and chew-swallowing2019

    • Author(s)
      Ogawa M, Kagaya H, Ozeki M, Kikumura K, Shibata S, Saitoh E.
    • Journal Title

      Japanese Journal of Comprehensive Rehabilitation Science

      Volume: 10 Issue: 0 Pages: 77-81

    • DOI

      10.11336/jjcrs.10.77

    • NAID

      130007733389

    • ISSN
      2185-5323
    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Feasibility of repetitive peripheral magnetic stimulation for dysphagia with reduced hyoid elevation: a report of two cases2019

    • Author(s)
      Mori S, Kagaya H, Nagashima Y, Toda F, Kuwabara A, Masuda Y, Sato Y, Ogawa M, Tsunoda T, Akahori R, Shibata S, Saitoh E.
    • Journal Title

      Jpn J Compr Rehabil Sci

      Volume: 10 Issue: 0 Pages: 42-46

    • DOI

      10.11336/jjcrs.10.42

    • NAID

      130007669554

    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] 摂食嚥下障害に対する末梢からの電気・磁気刺激療法2021

    • Author(s)
      加賀谷斉
    • Organizer
      第58回日本リハビリテーション医学会学術集会
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] 摂食嚥下障害に対する末梢からの電気・磁気刺激療法2020

    • Author(s)
      加賀谷 斉
    • Organizer
      第57回日本リハビリテーション医学会学術集会
    • Related Report
      2020 Research-status Report
    • Invited
  • [Presentation] Upper esophageal sphincter pressure at rest during magnetic stimulation of suprahyoid muscles in healthy individuals2019

    • Author(s)
      Kagaya H, Aihara K, Ogawa M, Nagashima Y, Aoyagi Y, Mori S, Toda F, Shibata S, Inamoto Y, Onogi K, Saitoh E.
    • Organizer
      13th International Society of Physical and Rehabilitation Medicine
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research

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Published: 2019-04-18   Modified: 2023-01-30  

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