• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Perioperative pain management strategies with sleep management

Research Project

Project/Area Number 19K18486
Research Category

Grant-in-Aid for Early-Career Scientists

Allocation TypeMulti-year Fund
Review Section Basic Section 56020:Orthopedics-related
Research InstitutionUniversity of Tsukuba

Principal Investigator

Mammoto Takeo  筑波大学, 医学医療系, 准教授 (30635206)

Project Period (FY) 2019-04-01 – 2023-03-31
Project Status Completed (Fiscal Year 2022)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2021: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2020: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2019: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords手術周術期管理 / 疼痛管理 / 睡眠管理 / 機能回復 / 患者満足度 / 手術周術期 / 周術期 / 疼痛 / 睡眠 / 術後疼痛
Outline of Research at the Start

術後疼痛は睡眠障害を招き、睡眠障害は疼痛そのものを増強する。また、術後鎮痛に用いられるオピオイドは睡眠に影響を与える。本研究では術後睡眠に対する影響を考慮した適切な術後疼痛の管理方法を確立するための方法を探索する。
<本研究の具体的な目的>
① 現在用いられている複合的術後鎮痛法(multimodal analgesia )を用いた術後疼痛患者の疼痛および睡眠の程度と状態・睡眠の質の実際を調査する。
② 術後疼痛の程度・睡眠状態・睡眠の質を分析し、疼痛が睡眠に及ぼす影響を調査する。
③ 術後疼痛の軽減と睡眠の状態・質の改善に向けた適切な方法を探求する。

Outline of Final Research Achievements

This study investigated acute pain, sleep status, and functional recovery during the perioperative period. It was confirmed that the greater the perioperative pain, the greater the amount of analgesic consumption and the worse the sleep status. The less invasive surgery resulted less pain and better functional recovery, but there were no differences in sleep status compared to the more invasive surgery. Questionnaire surveys suggested that it is necessary to consider the influence of mental status and environmental factors as factors that affect sleep status. A randomized controlled trial revealed that those with less pain used less amount of consumption of analgesics, had better sleep status, and had superior postoperative functional recovery.

Academic Significance and Societal Importance of the Research Achievements

術後疼痛は睡眠障害を招き、睡眠障害は疼痛を増強するが、これまで術後疼痛と睡眠状態について評価した研究は少ない。本研究では複合的術後鎮痛法を用いた術後疼痛患者の疼痛および睡眠の程度と状態・睡眠の質の実際を調査した。術後疼痛が強いと睡眠の質は低下し、機能回復が遅れることを明らかとした。術後疼痛は睡眠障害を引き起こし、肉体的・精神的疲労が引き起こされ、リハビリテーションが妨げられる。入院中のQOLは低下する。加えて入院期間が延長すれば、医療費の増加や社会生産性の低下などの損失を生み出す可能性があり、睡眠状態を考慮した適切な術後疼痛の管理方法を確立することが重要であることを示唆している。

Report

(5 results)
  • 2022 Annual Research Report   Final Research Report ( PDF )
  • 2021 Research-status Report
  • 2020 Research-status Report
  • 2019 Research-status Report
  • Research Products

    (20 results)

All 2023 2022 2021 2020 2019

All Journal Article (6 results) (of which Peer Reviewed: 5 results,  Open Access: 4 results) Presentation (14 results) (of which Int'l Joint Research: 12 results)

  • [Journal Article] Effects of zolpidem administration on postoperative pain in patients after total knee arthroplasty: Study protocol for a randomized controlled trial2022

    • Author(s)
      Mammoto Takeo、Taguchi Noriko、Takei Shunji、Imoo Yoshiyuki、Ma Enbo
    • Journal Title

      Archives of Clinical Trials

      Volume: 2 Issue: 2 Pages: 1-6

    • DOI

      10.33425/2768-4598.1020

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Pediatric pathological subtrochanteric fracture treated with an adult proximal humerus polyaxial locking plate: A case report2022

    • Author(s)
      Tsutsumi Ryosuke、Mammoto Takeo
    • Journal Title

      SAGE Open Medical Case Reports

      Volume: 10

    • DOI

      10.1177/2050313x221093112

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Effects of Magnetic Resonance Imaging With Axial Traction of the Thumb Carpometacarpal Joint on Articular Cartilage Visibility: A Feasibility Study2022

    • Author(s)
      Ikumi Akira、Kohyama Sho、Okuwaki Shun、Tatsumura Masaki、Hara Yuki、Mammoto Takeo、Ogawa Takeshi、Yoshii Yuichi、Kawamura Haruo、Yamazaki Masashi
    • Journal Title

      Cureus

      Volume: -

    • DOI

      10.7759/cureus.22421

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Rare Presentation of Angiolipoma Affecting an Intact Achilles Tendon2022

    • Author(s)
      Mammoto Takeo、Takahashi Nobuyuki、Takayashiki Norio
    • Journal Title

      Case Reports in Orthopedics

      Volume: 2022 Pages: 1-5

    • DOI

      10.1155/2022/6997320

    • Related Report
      2022 Annual Research Report 2021 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Short-Term Effects of Early Postoperative Celecoxib Administration for Pain, Sleep Quality, and Range of Motion After Total Knee Arthroplasty: A Randomized Controlled Trial2021

    • Author(s)
      Mammoto Takeo、Fujie Keiko、Taguchi Noriko、Ma Enbo、Shimizu Takeru、Hashimoto Koichi
    • Journal Title

      The Journal of Arthroplasty

      Volume: 36 Issue: 2 Pages: 526-531

    • DOI

      10.1016/j.arth.2020.08.018

    • Related Report
      2021 Research-status Report 2020 Research-status Report
    • Peer Reviewed
  • [Journal Article] セレコキシブ内服が術後早期の睡眠に与える影響 無作為化・無治療対照・並行群間比較試験2019

    • Author(s)
      万本 健生, 田口 典子, 馬見塚 尚孝, 平野 篤, 山崎 正志
    • Journal Title

      JOSKAS

      Volume: 44 Pages: 484-485

    • Related Report
      2019 Research-status Report
  • [Presentation] Postoperative Sleep Status after Total Knee Arthroplasty2023

    • Author(s)
      Takeo Mammoto
    • Organizer
      America Academy of Orthopaedic Surgeons
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Differences in Pain and Sleep Status between TKA and UKA2023

    • Author(s)
      Takeo Mammoto
    • Organizer
      Orthopaedic Research Society
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Differences in pain, sleep status and functional recovery between TKA and UKA2023

    • Author(s)
      Takeo Mammoto
    • Organizer
      European Federation of National Associations of Orthopaedics and Traumatology
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Differences in Pain, Sleep Status and Functional Recovery between TKA and UKA2023

    • Author(s)
      Takeo Mammoto
    • Organizer
      International Society of Arthroscopy, Knee Surgery and Orthopaedic Sports Medicine
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Postoperative Sleep Status aft er Total Knee Arthroplast2022

    • Author(s)
      Takeo Mammoto
    • Organizer
      America Academy of Orthopaedic Surgeons
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Perioperative Sleep Quality After Total Knee Arthroplasty.2022

    • Author(s)
      Takeo Mammoto
    • Organizer
      European Federation of National Associations of Orthopaedics and Traumatology
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Postoperative Sleep Quality After Total Knee Arthroplasty2022

    • Author(s)
      Takeo Mammoto
    • Organizer
      Orthopaedic Research Society
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Postoperative Sleep Status after Total Knee Arthroplasty2021

    • Author(s)
      Takeo Mammoto
    • Organizer
      American Academy of Orthopaedic Surgeons
    • Related Report
      2021 Research-status Report
    • Int'l Joint Research
  • [Presentation] Sleep Quality After Total Knee Arthroplasty.2021

    • Author(s)
      Takeo Mammoto
    • Organizer
      22nd EFORT Congress in Vienna, Austria
    • Related Report
      2021 Research-status Report
    • Int'l Joint Research
  • [Presentation] Postoperative Sleep Quality After Total Knee Arthroplasty2021

    • Author(s)
      Takeo Mammoto
    • Organizer
      Orthopaedic Research Society
    • Related Report
      2021 Research-status Report
    • Int'l Joint Research
  • [Presentation] Postoperative sleep disturbance in orthopaedic surgery2020

    • Author(s)
      Airi Suzuki, Takeo Mammoto, Kaori Kimura, Yukiko Maejima, Shumpei Suzuki, Masaki Tatsumura, Takeshi Ogawa and Atsushi Hirano
    • Organizer
      19 eme Reunion de la Societe Franco-Japonaise d’Orthopedie
    • Related Report
      2020 Research-status Report
    • Int'l Joint Research
  • [Presentation] Changes In Sleep Quality After Total Knee Arthroplasty.2020

    • Author(s)
      Takeo Mammoto
    • Organizer
      21st EFORT Annual Congress 2020
    • Related Report
      2020 Research-status Report
    • Int'l Joint Research
  • [Presentation] Ryosuke Tsutsumi, Takeo Mannmoto, Atsushi Hirano2020

    • Author(s)
      Surgical Outcome of TKA which Performed Distal Fumer Osteotomy Using Flexible Rod
    • Organizer
      JOSKAS-JOSSM 2020
    • Related Report
      2020 Research-status Report
  • [Presentation] Impact Of Early Administration Of Celecoxib On Postoperative Pain, Range Of Motion And Sleep Quality In Patients Undergoing Total Knee Arthroplasty: A Randomized Controlled Trial2019

    • Author(s)
      Takeo Mammoto,Keiko, Fujie, Noriko Taguchi, Koichi Hashimoto
    • Organizer
      European Federation of National Associations of Orthopaedics and Traumatology
    • Related Report
      2019 Research-status Report

URL: 

Published: 2019-04-18   Modified: 2024-01-30  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi