Nano-scale and real-time fluorescence imaging of metal-corrosion reaction dynamics

• Project/Area Number: 19K22118
• Research Category: Grant-in-Aid for Challenging Research (Exploratory)
• Allocation Type: Multi-year Fund
• Review Section: Medium-sized Section 28:Nano/micro science and related fields
• Research Institution: Rikkyo University
• Principal Investigator: MORIMOTO Masakazu 立教大学, 理学部, 教授 (70447126)
• Project Period (FY): 2019-06-28 – 2021-03-31
• Project Status: Completed (Fiscal Year 2020)
• Budget Amount: ¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000); Fiscal Year 2020: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000); Fiscal Year 2019: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
• Keywords: 金属材料 / 腐食 / 蛍光 / 蛍光イメージング

Outline of Research at the Start

本研究では、金属腐食反応のダイナミクスをナノメートルスケールの空間分解能でリアルタイムにイメージングする新手法の創出に挑戦する。新規に設計・合成する金属腐食プローブを用いた蛍光イメージングにより、極微小領域における金属腐食反応に関わる化学種を可視化し、金属腐食の時空間的・化学的発展過程をとらえる。将来におけるナノ材料・ナノデバイスの社会実装を目指す上で必要となる、ナノスケール・リアルタイム品質評価の革新的方法論の開拓へ向けた萌芽的研究に取り組む。

Outline of Final Research Achievements

In order to create a new method for real-time fluorescence imaging of metal corrosion reaction dynamics with nanometer-scale resolution, we aimed to establish design strategies for fluorescent molecular probes to visualize the spatial distribution of chemical species involved in metal corrosion. By studying the substituent effect on photoresponsive properties of photoswitchable fluorescent diarylethene derivatives, we obtained useful knowledge on control of absorption and fluorescence spectra, improvement of photostability, and proton-responsive functions toward rational design of fluorescent molecular probes.

Academic Significance and Societal Importance of the Research Achievements

本研究で見出した設計原理に基づくことで、水素イオンのみならず金属イオンに応答する分子を合成することも可能になると考えられる。光と様々な化学種に応答する多重機能性蛍光分子は、微小領域における金属腐食反応や細胞内における化学反応などのダイナミクスをイメージングするための蛍光プローブとして機能し、将来的には金属材料が関わる様々な産業分野や生物学・医学分野などに貢献する可能性を秘めている。

Research Products

• [Journal Article] Stepwise assembly of ultrathin poly(vinyl alcohol) films on photoresponsive diarylethene crystals (2021)
  • Author(s): Hiroka Chiba, Masakazu Morimoto, Masahiro Irie
  • Journal Title: Chemistry Letters Volume: 50 Issue: 1 Pages: 84-86
  • DOI: 10.1246/cl.200693
  • NAID: 130007965967
  • Peer Reviewed / Open Access
• [Journal Article] Photoinduced swing of a diarylethene thin broad sword shaped crystal: a study on the detailed mechanism (2020)
  • Author(s): Ayako Fujimoto, Noriko Fujinaga, Ryo Nishimura, Eri Hatano, Luna Kono, Akira Nagai, Akiko Sekine, Yohei Hattori, Yuko Kojima, Nobuhiro Yasuda, Masakazu Morimoto, Satoshi Yokojima, Shinichiro Nakamura, Ben L. Feringa, Kingo Uchida
  • Journal Title: Chemical Science Volume: 11 Issue: 45 Pages: 12307-12315
  • DOI: 10.1039/d0sc05388k
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Optical microresonator arrays of fluorescence-switchable diarylethenes with unreplicable spectral fingerprints (2020)
  • Author(s): Daichi Okada, Zhan-Hong Lin, Jer-Shing Huang, Osamu Oki, Masakazu Morimoto, Xuying Liu, Takeo Minari, Satoshi Ishii, Tadaaki Nagao, Masahiro Irie, Yohei Yamamoto
  • Journal Title: Materials Horizons Volume: 7 Issue: 7 Pages: 1801-1808
  • DOI: 10.1039/d0mh00566e
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Turn-on mode fluorescent diarylethenes: effect of electron-donating and electron-withdrawing substituents on photoswitching performance (2020)
  • Author(s): Ryota Iwai, Masakazu Morimoto, Masahiro Irie
  • Journal Title: Photochemical & Photobiological Sciences Volume: 19 Issue: 6 Pages: 783-789
  • DOI: 10.1039/d0pp00064g
  • Peer Reviewed
• [Journal Article] Object Transportation System Mimicking the Cilia of Paramecium aurelia Making Use of the Light‐Controllable Crystal Bending Behavior of a Photochromic Diarylethene (2019)
  • Author(s): Ryo Nishimura, Ayako Fujimoto, Nobuhiro Yasuda, Masakazu Morimoto, Tatsuhiro Nagasaka, Dr. Hikaru Sotome, Dr. Syoji Ito, Hiroshi Miyasaka, Satoshi Yokojima, Shinichiro Nakamura, Ben L. Feringa, Kingo Uchida
  • Journal Title: Angewandte Chemie International Edition Volume: 58 Issue: 38 Pages: 13308-13312
  • DOI: 10.1002/anie.201907574
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] An all-photonic full color RGB system based on molecular photoswitches (2019)
  • Author(s): Gaowa Naren, Chien-Wei Hsu, Shiming Li, Masakazu Morimoto, Sicheng Tang, Jordi Hernando, Gonzalo Guirado, Masahiro Irie, Francisco M. Raymo, Henrik Sunden, Joakim Andreasson
  • Journal Title: Nature Communications Volume: 10 Issue: 1
  • DOI: 10.1038/s41467-019-11885-4
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Presentation] Turn-on mode photoswitchable fluorescent molecules based on photochromic diarylethenes (2019)
  • Author(s): Masakazu Morimoto
  • Organizer: The 41st PhotonIcs & Electromagnetics Research Symposium
  • Int'l Joint Research / Invited
• [Presentation] Turn-on mode photoswitchable fluorescent diarylethenes: Substituent effect on photoswitching performance (2019)
  • Author(s): Masakazu Morimoto, Ryota Iwai, Shoya Takasu, Masahiro Irie
  • Organizer: 10th International Symposium on Photochromism
  • Int'l Joint Research
• [Remarks] 立教大学森本正和研究室ホームページ
  • URL: https://www2.rikkyo.ac.jp/web/m-morimoto/index.html