| Project/Area Number |
20200015
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| Research Category |
Grant-in-Aid for Scientific Research on Innovative Areas (Research a proposed research project)
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| Allocation Type | Single-year Grants |
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| Research Field |
Medical systems
Fluid engineering
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| Research Institution | Toyama National College of Maritime Technology |
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Principal Investigator |
HACHIGA Tadashi Toyama National College of Maritime Technology, 商船学科, 教授 (80123305)
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| Co-Investigator(Kenkyū-buntansha) |
ANDOH Tsugunobu 富山大学, 大学院・医学薬学研究部, 准教授 (50333498)
AKIGUCHI Shunsuke 富山高専, 電子情報工学科, 助教 (50462130)
ISHIDA Hiroki 富山高専, 電子情報工学科, 准教授 (50413761)
WAKISAKA Tomoyuki 大阪市立大学, 大学院・工学研究科, 客員教授 (10089112)
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| Co-Investigator(Renkei-kenkyūsha) |
KURAISHI Yasushi 富山大学, 大学院・医学薬学研究部, 教授 (80111970)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥28,730,000 (Direct Cost: ¥22,100,000、Indirect Cost: ¥6,630,000)
Fiscal Year 2010: ¥9,360,000 (Direct Cost: ¥7,200,000、Indirect Cost: ¥2,160,000)
Fiscal Year 2009: ¥9,360,000 (Direct Cost: ¥7,200,000、Indirect Cost: ¥2,160,000)
Fiscal Year 2008: ¥10,010,000 (Direct Cost: ¥7,700,000、Indirect Cost: ¥2,310,000)
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| Keywords | 検査・診断システム / 流体計測 / 血流速度 / レーザードップラー流速計 / 癌 / 血管血流速イメージング / 血流シミュレーション / レーザドップラー流速計 / 速度分布 / レーザ治療 |
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| Research Abstract |
We have developed a laser Doppler velocimeter to measure blood flow, named the Micro-Multi point Laser Doppler Velocimeter (μ MLDV). The μ MLDV was developed primarily for use in the diagnosis of cancer. We attempted to perform blood flow velocity imaging of a malignant melanoma which had been transplanted in the ear of a mouse. With this device we have succeeded in non-invasively measuring the blood flow velocity in microvessels. Moreover, we are able to measure absolute velocity and based on this can display the flow within blood vessels. Further experimentation confirmed the ability for the μ MLDV to be used as a heating device for cancer treatment. Cancer lesions are targeted by crossing the two laser beams producing overheating at the site of the malignant cells. The experimental results suggest that this device has the potential to become a new non-invasive diagnostic method for distinguishing benign nevi from malignant melanomas.
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