Development of photo-driven bionano-machines
Project/Area Number |
20200029
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Research Category |
Grant-in-Aid for Scientific Research on Innovative Areas (Research a proposed research project)
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Allocation Type | Single-year Grants |
Research Field |
Microdevices/Nanodevices
Biophysics
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Research Institution | Soka University |
Principal Investigator |
MARUTA Shinsaku Soka University, 工学部, 教授 (40231732)
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Project Period (FY) |
2008 – 2010
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Project Status |
Completed (Fiscal Year 2010)
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Budget Amount *help |
¥30,550,000 (Direct Cost: ¥23,500,000、Indirect Cost: ¥7,050,000)
Fiscal Year 2010: ¥10,530,000 (Direct Cost: ¥8,100,000、Indirect Cost: ¥2,430,000)
Fiscal Year 2009: ¥10,270,000 (Direct Cost: ¥7,900,000、Indirect Cost: ¥2,370,000)
Fiscal Year 2008: ¥9,750,000 (Direct Cost: ¥7,500,000、Indirect Cost: ¥2,250,000)
|
Keywords | ナノマシーン / 生体分子機械 / ナノマシン / 光駆動 / レーザー光 / バイオナノロボット / 生体分子 |
Research Abstract |
Photochromic molecules of azobenzene and spiropyran derivatives incorporated were incorporated into the functional sites of the bionanomachines, myosin, kinesin, calmodulin, G-protein Ras. The function of the bionanomachines modified with photochromic molecules were successfully controlled by Ultra-violet (UV) and visible (VIS) light. Reversibly. Moreover, we synthesized ATP analogue composed of photochromic molecule and revealed the analogue can induce ATP state, ADP state or no nucleotide state reversibly by UV-VIS light irradiation.
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Report
(4 results)
Research Products
(95 results)
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[Presentation] Conformational change of myosin head induced by phto-isomerization of photochromic ATP analogue2011
Author(s)
Itaba, T., Shishido, H., Sugimoto, Y., Wakabayashi, K., Maruta, S.
Organizer
第55回米国生物物理学会
Place of Presentation
Baltimore, MD USA.
Year and Date
2011-03-08
Related Report
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[Presentation] Conformational change of myosin head induced by phto-isomerization of photochromic ATP analogue2011
Author(s)
Itaba, T., Shishido, H., Sugimoto, Y., Wakabayashi, K., Maruta, S.
Organizer
第55回米国生物物理学会
Place of Presentation
Baltimore, MD USA
Year and Date
2011-03-08
Related Report
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[Presentation] Ca2+ dependent dimerization of kinesin-CaM and Kinesin-M13 fusion proteins2011
Author(s)
Nakazato, K., Shishido, H., Itaba, T., Kondo, K., Maruta, S.
Organizer
第55回米国生物物理学会
Place of Presentation
Baltimore, MD USA.
Year and Date
2011-03-06
Related Report
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[Presentation] Characterization of the plant-specific rice kinesins2011
Author(s)
Umezu, N., Umeki, N., Hanzawa, N., Kondo, K., Mitsui, T., Maruta, S.
Organizer
第55回米国生物物理学会
Place of Presentation
Baltimore, MD USA
Year and Date
2011-03-06
Related Report
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[Presentation] Ca2+ dependent dimerization of kinesin-CaM and Kinesin-M13 fusion proteins2011
Author(s)
Nakazato, K, Shishido, H., Itaba, T., Kondo, K., Maruta, S.
Organizer
第55回米国生物物理学会
Place of Presentation
Baltimore, MD USA
Year and Date
2011-03-06
Related Report
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[Presentation] KINESIN-CALMODULIN FUSION PROTEIN AS A MOLECULAR SHUTTLE AND MARKER FOR PLUS END OF MICROTUBULE2010
Author(s)
Itaba, T., Shishido, H., Nakazato, K., Katayama, E., Chaen, S., Maruta, S.
Organizer
第54回米国生物物理学会
Place of Presentation
San Francisco, CA USA.
Year and Date
2010-02-22
Related Report
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[Presentation] ANALYSIS OF CONFORMATION OF THE SKELETAL MUSCLE MYOSIN MODIFIED BY F_2DNB USING FRE2010
Author(s)
Yamada, M.D., Ishiyama, K., Katayama, E., Kimori, Y, Maruta, S.
Organizer
第54回米国生物物理学会
Place of Presentation
San Francisco, CA USA
Year and Date
2010-02-21
Related Report
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[Presentation] KINESIN-CALMODULIN FUSION PROTEIN AS A MOLECULAR SHUTTLE AND MARKER FOR PLUS END OF MICROTUBULE2010
Author(s)
Itaba, T., Shishido, H., Nakazato, K., Katayama, E., Chaen, S, Maruta, S.
Organizer
第54回米国生物物理学会
Place of Presentation
San Francisco, CA USA
Year and Date
2010-02-21
Related Report
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[Presentation] Kinesin-Calmodulin Fusion Protein as a Molecular Shuttle2009
Author(s)
Shishidol, H., Nakazato, K., Katayama, E., Chaen, S., Maruta, S.
Organizer
第49回米国細胞生物学会年会
Place of Presentation
San Diego, CA USA.
Year and Date
2009-12-07
Related Report
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[Presentation] Analysis of Conformation of the Skeletal Muscle Myosin Modified by Bifunctional Reagents Using FRET2009
Author(s)
Yamada, M.D., Ishiyama, K., Katayama, E., Kimori, Y, Maruta, S.
Organizer
第49回米国細胞生物学会年会
Place of Presentation
San Diego, CA USA
Year and Date
2009-12-06
Related Report
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[Presentation] Kinesin-Calmodulin Fusion Protein as a Molecular Shuttle2009
Author(s)
Shishidol, H., Nakazato, K., Katayama, E., Chaen, S, Maruta, S.
Organizer
第49回米国細胞生物学会年会
Place of Presentation
San Diego, CA USA
Year and Date
2009-12-06
Related Report
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