Budget Amount *help |
¥30,550,000 (Direct Cost: ¥23,500,000、Indirect Cost: ¥7,050,000)
Fiscal Year 2010: ¥10,530,000 (Direct Cost: ¥8,100,000、Indirect Cost: ¥2,430,000)
Fiscal Year 2009: ¥10,270,000 (Direct Cost: ¥7,900,000、Indirect Cost: ¥2,370,000)
Fiscal Year 2008: ¥9,750,000 (Direct Cost: ¥7,500,000、Indirect Cost: ¥2,250,000)
|
Research Abstract |
Photochromic molecules of azobenzene and spiropyran derivatives incorporated were incorporated into the functional sites of the bionanomachines, myosin, kinesin, calmodulin, G-protein Ras. The function of the bionanomachines modified with photochromic molecules were successfully controlled by Ultra-violet (UV) and visible (VIS) light. Reversibly. Moreover, we synthesized ATP analogue composed of photochromic molecule and revealed the analogue can induce ATP state, ADP state or no nucleotide state reversibly by UV-VIS light irradiation.
|