Investigation for the establishment of gender-sensitive geriatric medicine
| Project/Area Number |
20249041
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
General internal medicine (including Psychosomatic medicine)
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| Research Institution | The University of Tokyo |
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Principal Investigator |
OUCHI Yasuyoshi The University of Tokyo, 医学部附属病院, 教授 (80168864)
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| Co-Investigator(Kenkyū-buntansha) |
AKISHITA Masahiro 東京大学, 医学部附属病院, 准教授 (00261975)
ETO Masato 東京大学, 医学部附属病院, 特任准教授 (80282630)
IIJIMA Katsuya 東京大学, 医学部附属病院, 講師 (00334384)
OGAWA Sumito 東京大学, 医学部附属病院, 講師 (20323579)
OTA Hidetaka 東京大学, 医学部附属病院, 助教 (20431869)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥47,450,000 (Direct Cost: ¥36,500,000、Indirect Cost: ¥10,950,000)
Fiscal Year 2010: ¥12,480,000 (Direct Cost: ¥9,600,000、Indirect Cost: ¥2,880,000)
Fiscal Year 2009: ¥15,470,000 (Direct Cost: ¥11,900,000、Indirect Cost: ¥3,570,000)
Fiscal Year 2008: ¥19,500,000 (Direct Cost: ¥15,000,000、Indirect Cost: ¥4,500,000)
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| Keywords | 健康寿命延長 / 女性外来 / 性ホルモン / 性差 / 老年症候群 / 長寿遺伝子 |
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| Research Abstract |
This project was conducted to investigate the gender difference in age-related diseases and their pathogenesis. The study group examined and reported on the role of androgen receptor and Sirt1 in the process of aging, the gender difference and the role of sex hormones in frailty as well as in metabolic syndrome and atherosclerosis. Also, the questionnaire survey to hospitals revealed agendas and needs for the practical and educational system of gender-sensitive medicine.
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Report
(4 results)
Research Products
(39 results)
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[Journal Article] Induction of Endothelial Nitric Oxide Synthase, SIRT 1, and Catalase by Statins Inhibits Endothelial Senescence Through the Akt Pathway.2011
Author(s)
Ota H, Eto M, Kano MR, Kahyo T, Setou M, Ogawa S, Iljima K, AkishitaM, Ouchi Y.
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Journal Title
Arterioscler Thromb Vasc Biol.
Volume: in press(掲載確定)
Related Report
Peer Reviewed
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[Journal Article] Induction of endothelial nitric oxide synthase, SIRT1, and catalase by statins inhibits endothelial senescence through the Akt pathway2010
Author(s)
Ota H, Eto M, Kano MR, Kahyo T, Setou M, Ogawa S, Iijima K, Akishita M, Ouchi Y
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Journal Title
Arterioscler Thromb Vasc Biol. 30
Pages: 2205-11
Related Report
Peer Reviewed
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[Book] 新老年学 第3版2010
Author(s)
大内尉義, 秋山弘子, 折茂肇編
Total Pages
2142
Publisher
東京大学出版会・東京
Related Report
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