| Project/Area Number |
20300153
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (B)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Biomedical engineering/Biological material science
|
|---|
| Research Institution | Tokyo Medical and Dental University |
|---|
Principal Investigator |
TAKAKUDA Kazuo Tokyo Medical and Dental University, 生体材料工学研究所, 教授 (70108223)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
KOYAMA Yoshihisa 東京医科歯科大学, 生体材料工学研究所, 助教 (70361714)
NAGAI Masahiro 東京医科歯科大学, 生体材料工学研究所, 特任助教 (10013971)
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
MATSUMOTO Hiroko 東京医科歯科大学, 生体材料工学研究所, 技術補佐員 (70420263)
|
|---|
| Project Period (FY) |
2008 – 2010
|
| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥14,820,000 (Direct Cost: ¥11,400,000、Indirect Cost: ¥3,420,000)
Fiscal Year 2010: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2009: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2008: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
|
|---|
| Keywords | バイオメカニクス / 生体材料 / 組織工学 / 生体力学 / リモデリング |
|---|
| Research Abstract |
Fundamental investigations were performed to establish the design principles for the optimum mechanical characteristics of the tissue-regeneration devices. Specifically, the scaffold structures, the vascularizable structures, and the protective structures were developed for the regeneration of peripheral nerves, ligaments, periodontal tissues, and small caliber blood vessels. Experimental devices were created with the usages of bioabsorbable polymers as PLLA and their performances were examined in animal experiments.
|
