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Cineangiography Using Particle-Induced Dual-Wavelength Pulsed-X-rays for Minimization of Dosages of Contrast Medium and Radiation

Research Project

Project/Area Number 20300175
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Medical systems
Research InstitutionTokyo Institute of Technology

Principal Investigator

OGURI Yoshiyuki  東京工業大学, 原子炉工学研究所, 教授 (90160829)

Co-Investigator(Kenkyū-buntansha) HASEGAWA Jun  東京工業大学, 総合理工学研究科(研究院), 准教授 (90302984)
HORIOKA Kazuhiko  東京工業大学, 総合理工学研究科(研究院), 教授 (10126328)
Project Period (FY) 2008 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥19,110,000 (Direct Cost: ¥14,700,000、Indirect Cost: ¥4,410,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2010: ¥10,270,000 (Direct Cost: ¥7,900,000、Indirect Cost: ¥2,370,000)
Fiscal Year 2009: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2008: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Keywords荷電粒子励起特性 X 線 / 静電加速器 / 造影剤 / 動画撮影 / 二波長差分法 / 高コン トラスト撮影 / 被ばく線量 / 電子増倍型 CCD カメラ / 荷電粒子励起特性X線 / 陽子ビーム / 二波長差分 / 高コントラスト撮影 / 電子増倍型CCDカメラ / 荷電粒子励起X線放出 / 静電タンデム加速器 / 血管動画撮影 / コントラスト / 重粒子線 / シンチレーター / EMCCDカメラ / 負イオン源 / 特性X線
Research Abstract

We irradiated a rotating target with two metallic plates made of different elements by a MeV proton beam, and alternately produced quasi-monochromatic pulsed X-rays with two different energies: one was lower and the other was higher than the absorption-edge energy of the contrast medium. A cineradiograph of a phantom containing contrast medium was taken using these pulsed X-rays. A moving image which emphasized only the contrast medium was reconstructed by taking the difference between the adjacent frames. From this result, we found that the contrast-medium concentration and the X-ray dose for cineangiography could be reduced by applying this method.

Report

(7 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report   Self-evaluation Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (19 results)

All 2013 2012 2011 2010 2009 2008 Other

All Journal Article (8 results) (of which Peer Reviewed: 5 results) Presentation (11 results)

  • [Journal Article] Digital Subtraction Cineangiography Using Proton-Induced Quasi-Monochromatic Pulsed X-Rays2013

    • Author(s)
      Yoshiyuki Oguri
    • Journal Title

      International Journal of PIXE

      Volume: 23

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Transport Mechanism of MeV Protons in Tapered Glass Capillaries2011

    • Author(s)
      J. Hasegawa, S. Jaiyen, C. Polee,N. Chankow and Y. Oguri
    • Journal Title

      J. Appl. Phys

      Volume: 110 Issue: 4

    • DOI

      10.1063/1.3624617

    • Related Report
      2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Development of a Micro-PIXE System Using Tapered Glass Capillary Optics2011

    • Author(s)
      J.Hasegawa, S.Jaiyen, Y.Oguri
    • Journal Title

      Nuclear Instruments and Methods in Physics Research B in press

    • Related Report
      2010 Self-evaluation Report
  • [Journal Article] Development of a Micro-PIXE System Using Tapered Glass Capillary Optics2011

    • Author(s)
      J.Hasegawa, S.Jaiyen, Y.Oguri
    • Journal Title

      Nuclear Instruments and Methods B

      Volume: (印刷中)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] テーパーキャピラリーによるMeVイオン輸送の数値解析II2009

    • Author(s)
      長谷川純, 小栗慶之, 福田一志
    • Journal Title

      日本物理学会講演概要集第2分冊 64

      Pages: 64-64

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A Compact Micro-Beam System Using a Tapered Glass Capillary for Proton-Induced X-ray Radiography2008

    • Author(s)
      J.Hasegawa, S.Shiba, H.Fukuda, Y.Oguri
    • Journal Title

      Nuclear Instruments and Methods in Physics Research B 266

      Pages: 2125-2129

    • Related Report
      2010 Self-evaluation Report
  • [Journal Article] A Compact Micro-Beam System Using a Tapered Glass Capillary for Proton-Induced X-ray Radiography2008

    • Author(s)
      長谷川 純
    • Journal Title

      Nuclear Instruments and Methods in Physics Research B 266

      Pages: 2125-2129

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Digital Subtraction Cineangiography Using Proton-Induced Quasi-Monochromatic Pulsed X-Rays

    • Author(s)
      Y. Oguri, Y. Hu, K. Kondo, H. Fukuda, and J. Hasegawa
    • Journal Title

      Int. J. PIXE

      Volume: (掲載確定)

    • Related Report
      2012 Final Research Report
  • [Presentation] 被ばく線量と造影剤投与量の低い陽子線励起二波長パルスX線による血管動画撮影2012

    • Author(s)
      小栗慶之,胡宇超,近藤康太郎,福田一志,長谷川純
    • Organizer
      日本原子力学会2012年秋の大会予稿集
    • Place of Presentation
      広島大学東広島キャンパス
    • Related Report
      2012 Final Research Report
  • [Presentation] 陽子線励起準単色X線を用いた二波長差分法による血管動画造影の基礎研究2012

    • Author(s)
      小栗慶之
    • Organizer
      第28回PIXEシンポジウム
    • Place of Presentation
      東京工業大学(東京都)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 陽子線励起準単色X線を用いた二波長差分法による血管動画造影の基礎研究2011

    • Author(s)
      小栗慶之,胡宇超,近藤康太郎,福田一志,長谷川純
    • Organizer
      第28回PIXEシンポジウム
    • Place of Presentation
      東京工業大学
    • Year and Date
      2011-07-09
    • Related Report
      2012 Final Research Report
  • [Presentation] テーパーキャピラリーによるイオン集束とビーム品質の評価2010

    • Author(s)
      長谷川純, S.Jaiyen, 小栗慶之
    • Organizer
      日本物理学会2010年秋季大会
    • Place of Presentation
      大阪府立大学
    • Year and Date
      2010-09-26
    • Related Report
      2010 Annual Research Report 2010 Self-evaluation Report
  • [Presentation] Development of a μ-PIXE System Using Tapered Glass Capillary Optics2010

    • Author(s)
      J.Hasegawa, S.Jaiyen, Y.Oguri
    • Organizer
      10th European Conference on Accelerators in Applied Research and Technology
    • Place of Presentation
      Athens, Greece.
    • Year and Date
      2010-09-14
    • Related Report
      2010 Self-evaluation Report
  • [Presentation] Development of a μ-PIXE System Using Tapered Glass Capillary Optics2010

    • Author(s)
      J.Hasegawa, S.Jaiyen, Y.Oguri
    • Organizer
      10th European Conference on Accelerators in Applied Research and Technology
    • Place of Presentation
      Athens, Greece
    • Year and Date
      2010-09-14
    • Related Report
      2010 Annual Research Report
  • [Presentation] Monte-Carlo Simulation of Ion Beam Focusing Using Glancing-Angle Scattering2010

    • Author(s)
      J.Hasegawa, Y.Oguri, S.Jaiyen
    • Organizer
      The 18th International Symposium on Heavy Ion Inertial Fusion
    • Place of Presentation
      Darmstadt, Germany.
    • Year and Date
      2010-08-30
    • Related Report
      2010 Self-evaluation Report
  • [Presentation] Monte-Carlo Simulation of Ion Beam Focusing Using Glancing-Angle Scattering2010

    • Author(s)
      J.Hasegawa, Y.Oguri, S.Jaiyen
    • Organizer
      The 18th International Symposium on Heavy Ion Inertial Fusion
    • Place of Presentation
      Darmstadt, Germany
    • Year and Date
      2010-08-30
    • Related Report
      2010 Annual Research Report
  • [Presentation] A micro-PIXE analysis system based on taper capillary optics2009

    • Author(s)
      J.Hasegawa, C.Polee, H.Fukuda, Y.Oguri
    • Organizer
      20th International Congress on X-ray Optics and Microanalysis
    • Place of Presentation
      ドイツ・カールスルーエ,Congress Center Karlsruhe
    • Year and Date
      2009-09-16
    • Related Report
      2009 Annual Research Report
  • [Presentation] ガラスキヤピラリーを用いたマイクロPIXE装置の開発2008

    • Author(s)
      長谷川 純
    • Organizer
      第25回PIXEシンポジウム
    • Place of Presentation
      群馬大学医学部
    • Year and Date
      2008-09-11
    • Related Report
      2008 Annual Research Report
  • [Presentation] Preliminary Micro PIXE Analysis Using Glass Capillaries2008

    • Author(s)
      Chalermpong Polee
    • Organizer
      日本原子力学会2008年秋の大会
    • Place of Presentation
      高知工科大学
    • Year and Date
      2008-09-04
    • Related Report
      2008 Annual Research Report

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Published: 2008-04-01   Modified: 2019-07-29  

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