Fabrication of hollow microcapsules and their use as ultrasound contrast agents and drug delivery systems
| Project/Area Number |
20360093
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Thermal engineering
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| Research Institution | The University of Tokyo |
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Principal Investigator |
DAIGUJI Hirofumi The University of Tokyo, 大学院・新領域創成科学研究科, 准教授 (10302754)
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| Research Collaborator |
TAKEMURA Fumio 産業技術総合研究所, エネルギー技術研究部門, 主任研究員 (20313041)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥19,760,000 (Direct Cost: ¥15,200,000、Indirect Cost: ¥4,560,000)
Fiscal Year 2010: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2009: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2008: ¥10,400,000 (Direct Cost: ¥8,000,000、Indirect Cost: ¥2,400,000)
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| Keywords | 流体 / 化学物理 / 化学工学 |
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| Research Abstract |
Hollow microcapsules of biodegradable polymers with diameter less than 10 μm are expected to be used as ultrasound contrast agents or carriers for drug delivery systems in medical or pharmaceutical applications. In this study, a simple method was developed that uses microbubbles as templates to fabricate hollow microspheres covered with biodegradable polymers. We elucidated dominant factors affecting size and uniformity of hollow poly-lactic acid microcapsules and hollow polyelectrolytes microcapsules fabricated from microbubble templates.
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Report
(4 results)
Research Products
(16 results)
