Preparation of new chiral building blocks and their practical use in the enantioselective total synthesis of bioactive polycyclic natural products

• Project/Area Number: 20390006
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Chemical pharmacy
• Research Institution: Waseda University
• Principal Investigator: NAKADA Masahisa Waseda University, 理工学術院, 教授 (50198131)
• Co-Investigator(Kenkyū-buntansha): NOGUCHI Naoyoshi 早稲田大学, 理工学術院, 助手 (70454048)
• Project Period (FY): 2008 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥14,690,000 (Direct Cost: ¥11,300,000、Indirect Cost: ¥3,390,000); Fiscal Year 2010: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000); Fiscal Year 2009: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000); Fiscal Year 2008: ¥7,670,000 (Direct Cost: ¥5,900,000、Indirect Cost: ¥1,770,000)
• Keywords: 合成化学 / 全合成 / 有機化学

Research Abstract

Preparation of new chiral building blocks has advantage in the enantioselective total synthesis of naturally occurring important organic compounds (natural products) possessing diverse structures. In this research project, preparation methods of chiral building blocks via the catalysis with enzymes or chiral catalysts have been developed and they have been successfully applied to the enantioselective total synthesis of natural products including first syntheses. The chiral building blocks as well as their preparation methods will be used in the total synthesis of other natural products.

Research Products

• [Journal Article] Enantioselective Divergent Approaches to both (-)-Platensimycin and (-)-Platencin (2011)
  • Author(s): Hirai S.; Nakada M.
  • Journal Title: Tetrahedron 67 Pages: 518-530
  • Peer Reviewed
• [Journal Article] Enantioselective Divergent Approaches to both (-)-Platensimycin and (-)-Platencin (2011)
  • Author(s): Hirai, S.; Nakada, M.
  • Journal Title: Tetrahedron Volume: 67 Pages: 518-530
  • Peer Reviewed
• [Journal Article] An Enantioselective Approach to (-)-Platencin via Catalytic Asymmetric Intramolecular Cyclopropanation (2010)
  • Author(s): Hirai S.; Nakada M.
  • Journal Title: Tetrahedron Lett. 51 Pages: 5076-5079
  • Peer Reviewed
• [Journal Article] Synthetic Studies on Nemorosone via Enantioselective Intramolecular Cyclopropanation (2010)
  • Author(s): Abe M.; Saito A.; Nakada M.
  • Journal Title: Tetrahedron Lett. 51 Pages: 1298-1302
  • Peer Reviewed
• [Journal Article] Synthesis of NH006&#8212 A Photostable Fungicide Effective against Botrytis Cinerea&#8212 ; According to the Asymmetric Total Synthesis of MK8383 (2010)
  • Author(s): Hayashi, N.; Yamamoto, K.; Minowa, N.; Nakada, M.
  • Journal Title: Org.Biomol.Chem. Volume: 8 Pages: 1821-1825
  • Peer Reviewed
• [Journal Article] An Enantioselective Approach to (-)-Platencin via Catalytic Asymmetric Intramolecular Cyclopropanation (2010)
  • Author(s): Hirai, S.; Nakada, M.
  • Journal Title: Tetrahedron Lett. Volume: 51 Pages: 5076-5079
  • Peer Reviewed
• [Journal Article] Asymmetric Total Synthesis of MK3388 : The Iron-mediated Coupling Reaction is the Only Effective Method for the Conetruotion of the(2)-Trisubstituted Side-chain Alkene (2009)
  • Author(s): Hayashi, N., Nakada, M.
  • Journal Title: Tetrahedron Lett. 50 Pages: 232-235
  • Peer Reviewed
• [Journal Article] Alternative Synthetic Approach for(+)-Phomopsidin via the Highly Stereoselective TADA Reaction (2009)
  • Author(s): Hayashi, N., Suzuki, T., Usui, K., Nakada, M.
  • Journal Title: Tetrahedron 65 Pages: 888-895
  • Peer Reviewed
• [Journal Article] Total Synthesis of(-)-FR182877 through the Tandem IMDA-IMHDA Reaction and the Stereoselective Transition Metal-Mediated Transformations (2009)
  • Author(s): Tanaka, N., Suzuki, T., Matsumura, T., Hosoya, Y., Nakada, M.
  • Journal Title: Angew.Chem., Int.Ed. 48 Pages: 2580-2583
  • Peer Reviewed
• [Journal Article] Development of Catalytic Asymmetric Intramolecular Cyclopropanation for α-Diazo-β-Keto Sulfones and Applications to Natural Product Synthesis (2009)
  • Author(s): Honma, M., Takeda, H., Takano, M., Nakada, M.
  • Journal Title: Synlett Pages: 1695-1712
  • Peer Reviewed
• [Journal Article] 野崎-檜山-岸(NHK)反応有機クロム化合物の調製と反応 (2009)
  • Author(s): 中田雅久
  • Journal Title: 化学と教育 57 Pages: 410-411
  • Peer Reviewed
• [Journal Article] 抗腫瘍性化合物FR182877の不斉全合成 (2009)
  • Author(s): 中田雅久
  • Journal Title: ファルマシア 45 Pages: 451-456
  • Peer Reviewed
• [Journal Article] Asymmetric Total Synthesis of(+)-Carneic Acid A and Structure Revision of its Natural Form (2009)
  • Author(s): Yamakoshi, S., Hayashi, N., Suzuki, T., Nakada, M.
  • Journal Title: Tetrahedron Lett. 50 Pages: 5372-5375
  • Peer Reviewed
• [Journal Article] Structure Elucidation and Enantioselective Total Synthesis of the HMG-CoA Reductase Inhibitors, FR901512 and FR901516 (2009)
  • Author(s): Inoue, M., Nakada, M.
  • Journal Title: Synthesis Pages: 3694-3707
  • Peer Reviewed
• [Journal Article] Preparation of a Chiral Building Block with a Stereogenic Benzylic Quaternary Carbon Center and Formal Total Synthesis of (-)-Physostigmine (2008)
  • Author(s): Asakawa K.; Noguchi N.; Takashima S.; Nakada M.
  • Journal Title: Tetrahedron : Asymmetry 19 Pages: 2304-2309
  • Peer Reviewed
• [Journal Article] Total Synthesis of (+)-Allocyathin B_2, (-)-Erinacine B, and (-)-Erinacine E (2008)
  • Author(s): Watanabe H.; Takano M.; Nakada M.
  • Journal Title: J.Synth.Org.Chem. 66 Pages: 1116-1125
  • NAID: 10024409526
  • Peer Reviewed
• [Journal Article] Synthetic Studies on the Taxane Skeleton : Effective Construction of the Eight-membered Carbocyclic Ring by Palladium-catalyzed Intramolecular α-Alkenylation of Methyl Ketone (2008)
  • Author(s): Utsugi M.; Kamada Y.; Miyamoto H.; Nakada M.
  • Journal Title: Tetrahedron Lett. 49 Pages: 4754-4757
  • Peer Reviewed
• [Journal Article] Biomimetic Total Synthesis of (-)-Erinacine E (2008)
  • Author(s): Watanabe H.; Nakada M.
  • Journal Title: J.Am.Chem.Soc. 130 Pages: 1150-1151
  • Peer Reviewed
• [Journal Article] Synthetic Studies on (-)-Scabronine A (2008)
  • Author(s): Watanabe H.; Nakada M.
  • Journal Title: Tetrahedron Lett. 49 Pages: 1518-1522
  • Peer Reviewed
• [Journal Article] Synthetic studies on (-)- Scabronine A (2008)
  • Author(s): Watanabe, H., Nakada, M.
  • Journal Title: Tetrahedron Lett. 49 Pages: 1518-1522
  • Peer Reviewed
• [Journal Article] Biomimetic Total Synthesis of (-)- Erinaoine E (2008)
  • Author(s): Watanabe, H., Nakada, M.
  • Journal Title: J. Am. Chem. Soc. 130 Pages: 1150-1151
  • Peer Reviewed
• [Journal Article] Catalytic Asymmetric Nozaki-Hiyama Reactions with A Tridentate Bis (oxazolinyl) carbazoIe Ligand (2008)
  • Author(s): Inoue, M., Suzuki, T., Kinoshita, A., Nakada, M.
  • Journal Title: Chem. Reo. 8 Pages: 169-181
  • Peer Reviewed
• [Journal Article] Formal Total Synthesis of (-)- Physostigmine (2008)
  • Author(s): Asakawa, K., Noguchi, N., Nakada, M.
  • Journal Title: Heterocvcles 76 Pages: 183-190
  • NAID: 40016208560
  • Peer Reviewed
• [Journal Article] Synthetic studies on the Taxane Skeleton : Effective Construction of the Eight - metnbered Carbocyclic Ring by Palladium-catalyzed Intramolecular α-Alkenylation of Methyl Ketone (2008)
  • Author(s): Utsugi, M., Kamada, Y., Miyamoto, H., Nakada, M.
  • Journal Title: Tetrahedron Lett. 49 Pages: 4754-4757
  • Peer Reviewed
• [Journal Article] Total Synthesis of (+)-AIlocyathin B2, (-)-Erinaoine B, and (-)-Erinacine E (2008)
  • Author(s): Watanabe, H., Takano, M., Nakada, M.
  • Journal Title: J. Synth. Org. Chem. 66 Pages: 1116-1125
  • Peer Reviewed
• [Journal Article] Preparation of a Chiral BuiIding Block with a Stereogenio Benzylic Quaternary Carbon Center and Formal Total Synthesis of (-)- Physostigmine (2008)
  • Author(s): Asakawa, K., Noguohi, N., Takashima, S., Nakada, M.
  • Journal Title: Tetrahedron : Asymmetry 19 Pages: 2304-2309
  • Peer Reviewed
• [Journal Article] プラテンシマイシンは人類の救世主となるか? (2008)
  • Author(s): 中田雅久
  • Journal Title: 化学 63 Pages: 68-69
  • Peer Reviewed
• [Presentation] (+)-Ophiobolin Aの不斉全合成 (2011)
  • Author(s): 綱和宏、野口直義、中田雅久
  • Organizer: 日本化学会第91春季年会
  • Place of Presentation: 神奈川大学横浜キャンパス
  • Year and Date: 2011-03-29
• [Presentation] 共通キラル中間体を用いた(–)-platencinと(–)-platensimycinの形式不斉全合成 (2011)
  • Author(s): 平井祥、中田雅久
  • Organizer: 日本化学会第91春季年会
  • Place of Presentation: 神奈川大学横浜キャンパス
  • Year and Date: 2011-03-27
• [Presentation] Carneic Acid Aの不斉全合成およびその構造訂正 (2011)
  • Author(s): 山腰修平、林伸行、中田雅久
  • Organizer: 日本化学会第91春季年会
  • Place of Presentation: 神奈川大学横浜キャンパス
  • Year and Date: 2011-03-27
• [Presentation] Synthetic Studies on Antitumor Agent, Taxol (2011)
  • Author(s): Hirai, S.; Nakada, M.
  • Organizer: The 2th Symposium on Chiral Science & Technology : Mesochemistry & Chemical Wisdom
  • Place of Presentation: 早稲田大学西早稲田キャンパス
  • Year and Date: 2011-03-02
• [Presentation] First Enantioselective Total Synthesis of (+)-Ophiobolin A (2011)
  • Author(s): Tsuna, K.; Noguchi, N.; Nakada, M.
  • Organizer: The 2th Symposium on Chiral Science & Technology : Mesochemistry & Chemical Wisdom
  • Place of Presentation: 早稲田大学西早稲田キャンパス
  • Year and Date: 2011-03-02
• [Presentation] Synthetic Studies on Hyperforin (2011)
  • Author(s): Uwamori, M; Saito, A.; Nakada, M.
  • Organizer: The 2th Symposium on Chiral Science & Technology Mesochemistry & Chemical Wisdom
  • Place of Presentation: 早稲田大学西早稲田キャンパス
  • Year and Date: 2011-03-02
• [Presentation] Synthetic Studies on the Cyathane Core (2011)
  • Author(s): Orimoto, K.; Nakada, M.
  • Organizer: The 2th Symposium on Chiral Science & Technology : Mesochemistry & Chemical Wisdom
  • Place of Presentation: 早稲田大学西早稲田キャンパス
  • Year and Date: 2011-03-02
• [Presentation] Design, Synthesis, and Bioactivity of Tubulin-Binding Compounds (2011)
  • Author(s): Okajima, H.; Hosoya, Y.; Terada, Y.; Nakada, M.
  • Organizer: 生物学・化学・情報科学融合のための戦略的先進理工学研究基盤形成支援事業(FBT)第3回FBTシンポジウム
  • Place of Presentation: 早稲田大学西早稲田キャンパス
  • Year and Date: 2011-01-22
• [Presentation] Synthetic Studies on Antitumor Agent, Taxol (2011)
  • Author(s): Hirai, S.; Nakada, M.
  • Organizer: The 5th Global COE International Symposium on 'Practical Chemical Wisdom'
  • Place of Presentation: 早稲田大学西早稲田キャンパス
  • Year and Date: 2011-01-13
• [Presentation] First Enantioselective Total Synthesis of (+)-Ophiobolin A (2011)
  • Author(s): Tsuna, K.; Noguchi, N.; Nakada, M.
  • Organizer: The 5th Global COE International Symposium on 'Practical Chemical Wisdom'
  • Place of Presentation: 早稲田大学西早稲田キャンパス
  • Year and Date: 2011-01-13
• [Presentation] Synthetic Studies on Hyperforin (2011)
  • Author(s): Uwamori, M.; Saito, A.; Nakada, M.
  • Organizer: The 5th Global COE International Symposium on 'Practical Chemical Wisdom'
  • Place of Presentation: 早稲田大学西早稲田キャンパス
  • Year and Date: 2011-01-13
• [Presentation] Synthetic Studies on the Cyathane Core (2011)
  • Author(s): Orimoto, K.; Nakada, M.
  • Organizer: The 5th Global COE International Symposium on 'Practical Chemical Wisdom'
  • Place of Presentation: 早稲田大学西早稲田キャンパス
  • Year and Date: 2011-01-13
• [Presentation] (+)-ophiobolin Aの不斉全合成 (2011)
  • Author(s): 綱和宏、野口直義、中田雅久
  • Organizer: 日本化学会第91春季年会
  • Place of Presentation: 神奈川
• [Presentation] (+)-ophiobolin Aの不斉全合成研究 (2010)
  • Author(s): 綱和宏、野口直義、中田雅久
  • Organizer: 第36回反応と合成のシンポシンポジウム
  • Place of Presentation: 愛知県名古屋市
  • Year and Date: 2010-11-01
• [Presentation] 新合成ルートによるタキソールの収束的不斉全合成への挑戦 (2010)
  • Author(s): 中田雅久
  • Organizer: 理研シンポジウム第5回「有機合成化学のフロンティア」
  • Place of Presentation: 埼玉県和光市(招待講演)
  • Year and Date: 2010-07-09
• [Presentation] タキソールの収束的不斉全合成への挑戦 (2010)
  • Author(s): 中田雅久
  • Organizer: 第45回天然物談話会
  • Place of Presentation: 愛知県蒲郡市(招待講演)
  • Year and Date: 2010-07-06
• [Presentation] 同一中間体を経由する(–)-platencinと(–)-platensimycinの形式不斉全合成 (2010)
  • Author(s): 平井祥、中田雅久
  • Organizer: 第97回有機合成シンポジウム
  • Place of Presentation: 慶応大学薬学部
  • Year and Date: 2010-06-19
• [Presentation] (+)-ophiobolin Aの不斉全合成研究 (2010)
  • Author(s): 綱和宏、野口直義、中田雅久
  • Organizer: 第36回反応と合成のシンポシンポジウム
  • Place of Presentation: 名古屋
• [Presentation] 新合成ルートによるタキソールの収束的不斉全合成への挑戦 (2010)
  • Author(s): 中田雅久
  • Organizer: 理研シンポジウム第5回「有機合成化学のフロンティア」
  • Place of Presentation: 埼玉(招待講演)
• [Presentation] 同一中間体を経由する(-)-platencinと(-)-platensimycinの形式不斉全合成 (2010)
  • Author(s): 平井祥、中田雅久
  • Organizer: 第97回有機合成シンポジウム
  • Place of Presentation: 東京
• [Presentation] 連続反応を鍵工程とする生物活性多環式天然物の不斉全合成研究 (2010)
  • Author(s): 中田雅久
  • Organizer: 日本化学会第90春季年会
  • Place of Presentation: 大阪(特別講演)
• [Presentation] 連続反応を鍵工程とする生物活性多環式天然物の不斉全合成研究 (2010)
  • Author(s): 中田雅久
  • Organizer: 日本化学会第90春季年会(2010)
  • Place of Presentation: 大阪
• [Presentation] Nemorosoneの不斉全合成研究 (2009)
  • Author(s): 阿部正人、斎藤彩、中田雅久
  • Organizer: 第96回有機合成シンポジウム
  • Place of Presentation: 東京
• [Presentation] 有用な生物活性多環式天然物の精密不斉全合成に関する研究 (2009)
  • Author(s): 中田雅久
  • Organizer: 第95回有機合成化学シンポジウム
  • Place of Presentation: 東京(招待講演)
• [Presentation] (-)-platencinの形式不斉全合成 (2009)
  • Author(s): 平井祥、中田雅久
  • Organizer: 日本化学会第89春季年会
  • Place of Presentation: 千葉
• [Presentation] (+)-ophiobolin Aの不斉全合成研究 (2009)
  • Author(s): 綱和宏, 野口直義, 平井祥, 中田雅久
  • Organizer: 第57回有機合成化学協会関東支部シンポジウム
  • Place of Presentation: 東京
• [Presentation] (-)-carneic acid Aの不斉全合成研究 (2009)
  • Author(s): 山腰修平, 林伸行, 中田雅久
  • Organizer: 第57回有機合成化学協会関東支部シンポジウム
  • Place of Presentation: 東京
• [Presentation] (-)-platencin の形式不斉全合成 (2009)
  • Author(s): 平井祥, 中田雅久
  • Organizer: 第57回有機合成化学協会関東支部シンポジウム
  • Place of Presentation: 東京
• [Presentation] 有用な生物活性多環式天然物の精密不斉全合成に関する研究 (2009)
  • Author(s): 中田雅久
  • Organizer: 第95回有機合成シンポジウム
  • Place of Presentation: 東京
• [Presentation] 生物活性多環式天然物の不斉全合成 (2009)
  • Author(s): 中田雅久
  • Organizer: 中外製薬株式会社御殿場研究所学術講演会
  • Place of Presentation: 静岡
• [Presentation] 有用な生物活性天然物の精密不斉全合成に関する研究 (2009)
  • Author(s): 中田雅久
  • Organizer: アステラス製薬株式会社化学研究所学術講演会
  • Place of Presentation: つくば
• [Presentation] Studies on Enantioselective Total Synthesis of(+)-Ophiobolin A (2009)
  • Author(s): 綱和宏, 野口直義, 中田雅久
  • Organizer: The Symposium on Chiral Science & Technology : Mesochemistry & Chemical Wisdom
  • Place of Presentation: 東京
• [Presentation] Asymmetric Total Synthesis of(+)-Carneic Acid A and Structure Revision of its Natural Form (2009)
  • Author(s): 山腰修平, 林伸行, 中田雅久
  • Organizer: The Symposium on Chiral Science & Technology : Mesochemistry & Chemical Wisdom
  • Place of Presentation: 東京
• [Presentation] Nemorosone の不斉全合成研究 (2009)
  • Author(s): 阿部正人, 斎藤彩, 中田雅久
  • Organizer: 第96回有機合成シンポジウム
  • Place of Presentation: 東京
• [Presentation] Synthetic Studies on Cyathane Diterpenoids (2009)
  • Author(s): 折本浩平, 中田雅久
  • Organizer: The 4th Global COE International Symposium on "Practical Chemical Wisdom"
  • Place of Presentation: 東京
• [Presentation] Studies on Enantioselective Total Synthesis of(+)-Ophiobolin A (2009)
  • Author(s): 綱和宏, 野口直義, 中田雅久
  • Organizer: The 4th Global COE International Symposium on "Practical Chemical Wisdom"
  • Place of Presentation: 東京
• [Presentation] Enantioselective Formal Total Synthesis of Platencin and Platensimycin via the Same Chiral Intermediate (2009)
  • Author(s): 平井祥, 中田雅久
  • Organizer: The 4th Global COE International Symposium on "Practical Chemical Wisdom"
  • Place of Presentation: 東京
• [Presentation] 抗菌活性天然物(+)- phomopsidinおよびその同族体であるMK8383の新規農園芸剤開発を志向した構造活性相関研究 (2009)
  • Author(s): 林伸行, 中田雅久, 山本憲太朗, 尾山和彦, 箕輪宣人, 三冨正明
  • Organizer: 日本化学会第89春季年会
  • Place of Presentation: 日大船橋、千葉
• [Presentation] (+)- ophiobolin A の不斉全合成研究-8員環の新規構築法の開発- (2009)
  • Author(s): 綱和宏, 平井祥, 野口直義, 中田雅久
  • Organizer: 日本化学会第89春季年会
  • Place of Presentation: 日大船橋、千葉
• [Presentation] (-)-platencinの形式不斉全合成 (2009)
  • Author(s): 平井祥, 中田雅久
  • Organizer: 日本化学会第89春季年会
  • Place of Presentation: 日大船橋、千葉
• [Presentation] (-)-oarneio acid Aの不斉全合成研究 (2009)
  • Author(s): 山腰修平, 林伸行, 中田雅久
  • Organizer: 日本化学会第89春季年会
  • Place of Presentation: 日大船橋、千葉
• [Presentation] 光安定性の向上を目的とした殺菌活性化合物MK8383の誘導体化 (2009)
  • Author(s): 山本憲太朗, 尾山和彦, 箕輪宣人, 三冨正明, 林伸行, 中田雅久
  • Organizer: 日本農薬学会第34回大会
  • Place of Presentation: 東京大学、東京
• [Presentation] 新合成ルートによるタキソールの収束的不斉全合成への挑戦 (2008)
  • Author(s): 中田雅久
  • Organizer: 高知大学学術講演会
  • Place of Presentation: 高知(招待講演)
• [Presentation] Studies on Asymmetric Total Synthesis of Hyperforin (2008)
  • Author(s): 阿部正人、中田雅久
  • Organizer: The 2nd Global COE International Symposium on 'Practical Chemical Wisdom'
  • Place of Presentation: 東京
• [Presentation] タキソールの不斉全合成研究 (2008)
  • Author(s): 鎌田恭明、宇津木雅之、中田雅久
  • Organizer: 第93回有機合成シンポジウム
  • Place of Presentation: 東京
• [Presentation] MK8383の不斉全合成 (2008)
  • Author(s): 林伸行, 中田雅久
  • Organizer: 第55回有機合成化学協会関東シンポジウム
  • Place of Presentation: 東京理大、千葉
• [Presentation] タキソールの不斉全合成研究 (2008)
  • Author(s): 鎌田恭明, 宇津木雅之, 中田雅久
  • Organizer: 第93回有機合成シンポジウム
  • Place of Presentation: 東京工業大学、東京
• [Presentation] 生物活性多環式天然物の収束的不斉全合成 (2008)
  • Author(s): 中田雅久
  • Organizer: 文部科学省科学研究費補助金特定領域研究「生体機能分子の創製」取りまとめシンポジウム(東京)
  • Place of Presentation: 船堀、東京
• [Presentation] Enantioselective Total Synthesis of Bioactive PoIycycIic Natural Products (2008)
  • Author(s): 中田雅久
  • Organizer: The 2nd Global COE International Symposiun on ‘Practical Chemical Wisdom'
  • Place of Presentation: 早稲田大学、東京
• [Presentation] Asymmetric Total Synthesis of (&#8211 ; )-FR182877 (2008)
  • Author(s): 田中奈津美, 鈴木孝弘, 松村岳彦, 細谷洋介, 中田雅久
  • Organizer: The 2nd Global COE International Symposium on ‘Practical Chemical Wisdom'
  • Place of Presentation: 早稲田大学、東京
• [Presentation] studies on Enantioselective Total Synthesis of (+)- Ophiobolin (2008)
  • Author(s): 野口直義, 綱和宏, 中田雅久
  • Organizer: The 2nd Global COE International Symposium on ‘Practical Chemical
  • Place of Presentation: 早稲田大学、東京
• [Presentation] studies on Asymmetric Total Synthesis of Hyperforin (2008)
  • Author(s): 阿部正人, 中田雅久
  • Organizer: The 2nd Global COE International Symposium on ‘Practical Chemical Wisdom'
  • Place of Presentation: 早稲田大学、東京
• [Presentation] Total Synthesis of MK8383 and Its Structure-Activity ReIationships (2008)
  • Author(s): 林伸行, 中田雅久
  • Organizer: The 2nd Global COE International Symposium on ‘Practical Chemical Wisdom'
  • Place of Presentation: 早稲田大学、東京
• [Presentation] 新合成ルートによるタキソールの収束的不斉全合成への挑戦 (2008)
  • Author(s): 中田雅久
  • Organizer: 高知大学学術講演会
  • Place of Presentation: 高知大学、高知
• [Presentation] 抗腫瘍性化合物(-)- FR182877の不斉全合成 (2008)
  • Author(s): 田中奈津美, 鈴木孝弘, 松村岳彦, 細谷洋介, 中田雅久
  • Organizer: 第50回天然有機化合物討論会
  • Place of Presentation: 福岡国際会議場、福岡
• [Presentation] 抗腫瘍性化合物(-)- FR182877の不斉全合成 (2008)
  • Author(s): 田中奈津美, 鈴木孝弘, 松村岳彦, 細谷洋介, 中田雅久
  • Organizer: 2008若手研究者のためのセミナー
  • Place of Presentation: 東京工業大学、東京
• [Presentation] 抗腫瘍性化合物(- FR182877の不斉全合成 (2008)
  • Author(s): 田中奈津美, 鈴木孝弘, 松村岳彦, 細谷洋介, 中田雅久
  • Organizer: 第94回有機合成シンポジウム
  • Place of Presentation: 早稲田大学、東京
• [Presentation] (-)- platencinの形式不斉全合成 (2008)
  • Author(s): 平井祥, 中田雅久
  • Organizer: 第56回有機合成化学協会関東支部シンポジウム(新潟シンポジウム)
  • Place of Presentation: 新潟大学、新潟
• [Remarks] ホームページ等
  • URL: http://www.chem.waseda.ac.jp/nakada/
• [Remarks]
  • URL: http://www.chem.waseda.ac.jp/nakada/