• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Novel advances of adiponectin signal transduction network

Research Project

Project/Area Number 20390254
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Metabolomics
Research InstitutionThe University of Tokyo

Principal Investigator

YAMAUCHI Toshimasa  The University of Tokyo, 医学部附属病院, 講師 (40372370)

Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥19,110,000 (Direct Cost: ¥14,700,000、Indirect Cost: ¥4,410,000)
Fiscal Year 2010: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2009: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2008: ¥10,010,000 (Direct Cost: ¥7,700,000、Indirect Cost: ¥2,310,000)
Keywordsアディポネクチン / シグナル情報伝達 / 動脈硬化 / インスリン / AdipoR / 糖代謝 / 脂質代謝
Research Abstract

Adiponectin induces extracellular Ca influx by adiponectin receptor 1 (AdipoR1), which was necessary for subsequent activation of CaMKKb and AMPK, increased expression PGC-1a, and increased mitochondria in myocytes. Moreover, muscle-specific disruption of AdipoR1 suppressed the adiponectin-mediated increase in intracellular Ca concentration, and decreased the activation of CaMKK and AMPK by adiponectin. Suppression of AdipoR1 also resulted in decreased PGC-1a expression, decreased mitochondrial content and enzymes, and decreased oxidative type I myofibres in skeletal muscle, which were associated with insulin resistance and decreased exercise endurance (Nature 464 : 1313,2010). Decreased levels of adiponectin and AdipoR1 in obesity may have causal roles in mitochondrial dysfunction and insulin resistance seen in diabetes.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (46 results)

All 2011 2010 2009 2008

All Journal Article (24 results) (of which Peer Reviewed: 24 results) Presentation (22 results)

  • [Journal Article] Adiponectin receptor signaling : a new layer to the current model.2011

    • Author(s)
      Kadowaki T, Yamauchi T
    • Journal Title

      Cell Metabolism 13

      Pages: 123-124

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Adiponectin receptor signaling : a new layer to the current model.2011

    • Author(s)
      Kadowaki T, Yamauchi T.
    • Journal Title

      Cell Meabolism

      Volume: 13 Pages: 123-124

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The diabetogenic VPS13C/C2CD4A/C2CD4B rs7172432 variant impairs glucose-stimulated insulin response in 5,722 non-diabetic Danish individuals.2011

    • Author(s)
      Grarup N, Overvad M, Sparso T, Witte DR, Oisinger C, Jorgensen T, Yamauchi T, Hara K, Maeda S, Kadowaki T, Hansen T, Pedersen O.
    • Journal Title

      Diabetologia

      Volume: 54 Pages: 789-794

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Adiponectin and AdipoR1 regulate PGC-1α and mitochondria by Ca^<2+> and AMPK/SIRT1.2010

    • Author(s)
      Iwabu M, Yamauchi T, Okada-Iwabu M, Sato K, Nakagawa T, Funata M, Yamaguchi M, Namiki S, Nakayama R, Tabata M, Ogata H, Kubota N, Takamoto I, Hayashi K.Y, Yamauchi N, Waki H, Fukayama M, Nishino I, Tokuyama K, Ueki K, Oike Y, Ishii S, Hirose K, Shimizu T, Touhara K, Kadowaki T
    • Journal Title

      Nature 434

      Pages: 1313-1319

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Adiponectin suppresses tumorigenesis in Apc(Min)(/+) mice.2010

    • Author(s)
      Otani K, Kitayama J, Yasuda K, Nio Y, Iwabu M, Okudaira S, Aoki J, Yamauchi T, Kadowaki T, Nagawa H
    • Journal Title

      Cancer Letter 288(2)

      Pages: 177-182

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Adiponectin and AdipoR1 regulate PGC-lalpha and mitochondria by Ca(2+) and AMPK/SIRT12010

    • Author(s)
      Iwabu M, Yamauchi T, Okada-Iwabu M, Sato K, Nakagawa T, Funata M, Yamaguchi M, Namiki S, Nakayama R, Tabata M, Ogata H, Kubota N, Takamoto I, Hayashi YK, Yamauchi N, Waki H, Fukayama M, Nis hino I, Tokuyama K, Ueki K, Oike Y, Ishii S, Hirose K, Shimizu T, Touhara K, Kadowaki T.
    • Journal Title

      Nature

      Volume: 464 Pages: 1313-1319

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B2010

    • Author(s)
      Yamauchi T, Hara K, Maeda S, Yasuda K, Takahashi A, Horikoshi M, Nakamura M, Fujita H, Grarup N, Cauchi S, Ng DP, Ma RC, Tsunoda T, Kubo M, Watada H, Maegawa H, Okada-Iwabu M, Iwabu M, Shojima N, Shin HD, Andersen G, Witte DR, Jorgensen T, Lauritzen T, Sandbwk A, Hansen T, Ohshige T, Omori S, Saito I, Kaku K, Hirose H, So WY, Beury D, Chan JC, Park KS, Tai ES, Ito C, Tanaka Y, Kashiwagi A, Kawamori R, Kasuga M, Froguel P, Pedersen O, Kamatani N, Nakamura Y, Kadowaki T
    • Journal Title

      Nature Genetics

      Volume: 42 Pages: 864-868

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Adiponectin receptors are downregulated in human gastric cancer.2010

    • Author(s)
      Otani K, Kitayama J, Kamei, T, Soma D, Miyato H, Yamauchi T, Kadowaki T, Nagawa H
    • Journal Title

      Journal of Gastroenterology

      Volume: 45 Pages: 918-927

    • NAID

      10027698901

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Adiponectin and AdipoR1 regulate PGC-lalpha and mitochondria by Ca(2+)and AMPK/SIRT1.2010

    • Author(s)
      Iwabu M, Yamauchi T, Okada-Iwabu M, Sato K, Nakagawa T, Funata M, Yamaguchi M, Namiki S, Nakayama R, Tabata M, Ogata H, Kubota N, Takamoto I, Hayashi YK, Yamauchi N, Waki H, Fukayama M, Nishino I, Tokuyama K, Ueki K, Oike Y, Ishii S, Hirose K, Shimizu T, Touhara K, Kadowaki T.
    • Journal Title

      Nature (published online Mar.31,2010)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Adiponectin suppresses tumorigenesis in Apc(Min)(/+)mice.2010

    • Author(s)
      Otani K, Kitayama J, Yasuda K, Nio Y, Iwabu M, Okudaira S, Aoki J, Yamauchi T, Kadowaki T, Nagawa H.
    • Journal Title

      Cancer Lett. 288

      Pages: 177-182

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Peroxisome proliferator-activated receptor γ agonist rosiglitazone increases expression of very low density lipoprotein receptor gene in adipocytes.2009

    • Author(s)
      Takazawa T, Yamauchi T, Tsuchida A, Takata M, Hada Y, Iwabu M, Okada-Iwabu M, Ueki K, Kadowaki T
    • Journal Title

      The Journal of Biological Chemistry 284

      Pages: 30049-30057

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Adiponectin suppresses hepatic SREBP1c expression in an AdipoR1/LKB1/AMPK dependent pathway.2009

    • Author(s)
      Awazawa M, Ueki K, Inabe K, Yamauchi T, Kaneko K, Okazaki Y, Bardeesy N, Ohnishi S, Nagai R, Kadowaki T
    • Journal Title

      Biochemical and Biophysical Research Communications 382

      Pages: 51-56

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Rimonabant Ameliorates Insulin Resistance via both Adiponectin-dependent and Adiponectin-independent Pathways.2009

    • Author(s)
      Watanabe T, Kubota N, Ohsugi M, Kubota T, Takamoto I, Iwabu M, Awazawa M, Katsuyama H, Hasegawa C, Tokuyama K, Moroi M, Sugi K, Yamauchi T, Noda T, Nagai R, Terauchi Y, Tobe K, Ueki K, Kadowaki T
    • Journal Title

      The Journal of Biological Chemistry 284

      Pages: 1803-1812

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Peroxisome proliferator-activated receptor gamma agonist rosiglitazone increases the expression of very low density lipoprotein receptor gene in adipocytes.2009

    • Author(s)
      Takazawa T, Yamauchi T, Tsuchida A, Takata M, Hada Y, Iwabu M, Okada-Iwabu M, Ueki K, Kadowaki T
    • Journal Title

      J Biol Chem 284

      Pages: 30049-30057

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Reconsideration of insulin signals induced by improved laboratory animal diets, Japanese and American diets, in IRS-2 deficcient mice.2009

    • Author(s)
      Hashimoto H, Arai T, Mori A, Kawai K, Hikishima K, Ohnishi Y, Eto T, Ito M, Hioki K, Suzuki R, Ohsugi M, Saito M, Ueyama Y, Okano H, Yamauchi T, Kubota N, Ueki K, Tobe K, Tamaoki N, Kadowaki T, Kosaka K
    • Journal Title

      Exp Clin Endocrinol Diabetes 117

      Pages: 577-586

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Adiponectin suppresses hepatic SREBP1c expression in an AdipoRi/LKB1/AMPK dependent pathway.2009

    • Author(s)
      Awazawa M, Ueki K, Inabe K, Yamauchi T, Kaneko K, Okazaki Y, Bardeesy N, Ohnishi S, Nagai R, Kadowaki T
    • Journal Title

      Biochem Biophys Res Commun 382

      Pages: 51-56

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Adiponectin suppresses hepatic SREBP1c expression in an AdipoRl/LKB1/AMPK dependent pathway.2009

    • Author(s)
      Awazawa M, Ueki K, Inane K, Yamauchi T, Kaneko K, Okazaki Y, Bardeesy N, Ohnishi S, Nagai R, Kadowaki T.
    • Journal Title

      Biochem Biophys Res Commun (in press)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Rimonabant ameliorates insulin resistance via both adiponectin-dependent and adiponectin-independent pathways2009

    • Author(s)
      Watanabe T, Kubota N, Ohsugi M, Kubota T, Takamoto I, Iwabu M, Awazawa M, Katsuyama H, Hasegawa C, Tokuyama K, Moroi M, Sugi K, Yamauchi T, Noda T, Nagai R, Terauchi Y, Tobe K, Ueki K, Kadnwaki T
    • Journal Title

      J Blot Chem 284

      Pages: 1803-1812

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Adiponectin suppresses colorectal carcinogenesis under the high-fat diet condition.2008

    • Author(s)
      Fujisawa T, Endo H, Tomimoto A, Sugiyama M, Takahashi H, Saito S, Inamori M, Nakajima N, Watanabe M, Kubota N, Yamauchi T, Kadowaki T, Wada K, Nakagama H, Nakajima A
    • Journal Title

      Gut 57

      Pages: 1531-1538

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 5-Hydroxytryptamine 2A receptor signaling cascade modulates adiponectin and plasminogen activator inhibitor 1 expression in adipose tissue.2008

    • Author(s)
      Uchida-Kitajima S, Yamauchi T, Takashina Y, Okada-Iwabu M, Iwabu M, Ueki K, Kadowaki T
    • Journal Title

      FEBS Letters 582

      Pages: 3037-3044

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Adiponectin suppresses colorectal carcinogenesis under the high-fat diet condition.2008

    • Author(s)
      Fujisawa T, Endo H, Tomimoto A, Sugiyama M, Takahashi H, Saito S, Inamori M, Nakajima N, Watanabe M, Kubota N, Yamauchi T, Kadowaki T, Wada K, Nakagama H, Nakajima A.
    • Journal Title

      Gut 57

      Pages: 1531-1538

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 5-Hydroxytryptamine 2A receptor signaling cascade modulates adiponectin and plasminogen activator inhibitor 1 expression in adipose tissue.2008

    • Author(s)
      Uchida-Kitajima S, Yamauchi T, Takashina Y, Okada-Iwabu M, Iwabu M, Ueki K, Kadowaki T.
    • Journal Title

      FEBS Lett 582

      Pages: 3037-3044

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] An Efficient reproductive method for Irs2-/-mice with C57BL/6JJclgenetic background.2008

    • Author(s)
      Hashimoto H, Eto T, Kamisako T, Hoya N, Hatakeyama T, Arai T, Yokosuka M, Ohnishi Y, Ito M, Hioki K, Suzuki R, Ohsugi M, Saito M, Ueyama Y, Yamauchi T, Kubota N, Tobe K, Kadowaki T, Tamaoki N, Nomura T, Kosaka K.
    • Journal Title

      Exp Anim 57

      Pages: 407-411

    • NAID

      10024166620

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Fulminant type 1 diabetes mellitus observed in insulin receptor substrate 2 deficient mice2008

    • Author(s)
      Arai T, Hashimoto H, Kawai K, Mori A, Ohnishi Y, Hioki K, Ito M, Saito M, Ueyama Y, Ohsugi M, Suzuki R, Kubota N, Yamauchi T, Tobe K. Kadowaki T, Kosaka K.
    • Journal Title

      Clin Exp Med 8

      Pages: 93-99

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Presentation] 代謝に重要な各組織におけるアディポネクチン受容体を介した細胞内情報伝達の解析2010

    • Author(s)
      山内敏正、岩部美紀、岩部真人、窪田直人、植木浩二郎、門脇孝
    • Organizer
      第31回日本肥満学会
    • Place of Presentation
      前橋
    • Year and Date
      2010-10-02
    • Related Report
      2010 Final Research Report
  • [Presentation] 代謝に重要な各組織におけるアティポネクチン受容体を介した細胞内情報伝達の解析2010

    • Author(s)
      山内敏正, 岩部美紀, 岩部真人, 窪田直人, 植木浩二郎, 門脇孝
    • Organizer
      第31回日本肥満学会
    • Place of Presentation
      煥乎堂(前橋市)
    • Year and Date
      2010-10-02
    • Related Report
      2010 Annual Research Report
  • [Presentation] Signal Transduction Mechanisms by Which Adiponectin/AdipoR1 Active AMPK, SIRT1 and PGC-1alpha, Leading to Increased Mitochondrial Bioenergetics in Muscle Cells.2010

    • Author(s)
      山内敏正, 岩部真人, 岩部美紀, 植木浩二郎, 門脇孝
    • Organizer
      The 70^<th> Scientific Sessions of the American Diabetes Association 2010
    • Place of Presentation
      Florida, USA
    • Year and Date
      2010-06-28
    • Related Report
      2010 Final Research Report
  • [Presentation] Signal Transduction Mechanisms by Which Adiponectin/AdipoR1 Active AMP K, SIRT1 and PGC-lalpha, Leading to Increased Mitochondrial Bioenergetics in Muscle Cells.2010

    • Author(s)
      Toshimasa Yamauchi, Masato Iwabu, Miki Iwahu, Kohjiro Ueki, Takashi Kadowaki
    • Organizer
      The 70^<th> Scientific Sessions of the American Diabetes Association 2010
    • Place of Presentation
      Florida, USA
    • Year and Date
      2010-06-28
    • Related Report
      2010 Annual Research Report
  • [Presentation] Progress in Metabolic Syndrome Research 2010「Pathophysiological roles of adiponectin and AdipoRs in metabolic syndrome」2010

    • Author(s)
      山内敏正
    • Organizer
      第53回日本糖尿病学会年次学術集会
    • Place of Presentation
      岡山
    • Year and Date
      2010-05-27
    • Related Report
      2010 Final Research Report
  • [Presentation] Pathophysiological roles of adiponectin and AdipoRs in metabolic syndrome2010

    • Author(s)
      山内敏正
    • Organizer
      第53回日本糖尿病学会年次学術集会シンポジウムProgress in Metabolic Syndrome Research 2010
    • Place of Presentation
      岡山全日空ホテル(岡山市)
    • Year and Date
      2010-05-27
    • Related Report
      2010 Annual Research Report
  • [Presentation] アディポネクチン受容体AdipoRと2型糖尿病2009

    • Author(s)
      山内敏正、門脇孝
    • Organizer
      第30回日本肥満学会
    • Place of Presentation
      浜松
    • Year and Date
      2009-10-09
    • Related Report
      2010 Final Research Report 2009 Annual Research Report
  • [Presentation] Targeted Disruption of Adiponectin Receptor AdipoR2 in Endothelial Cells Reduced PPARgamma and Increased Neointimal Formation.2009

    • Author(s)
      山内敏正, 岩部美紀, 岩部真人, 窪田直人, 植木浩二郎, 門脇孝
    • Organizer
      The 69^<th> Scientific Sessions of the American Diabetes Association 2009
    • Place of Presentation
      Louisiana, USA
    • Year and Date
      2009-06-07
    • Related Report
      2010 Final Research Report
  • [Presentation] Muscle-Specific Disruption of AdipoR1 Reduced pAMPK PGC-1Mitochondrial Biogenesis2009

    • Author(s)
      山内敏正, 岩部真人, 岩部美紀, 窪田直人, 植木浩二郎, 門脇孝
    • Organizer
      Slow Twitch Muscle Fibers, Insulin Sensitivity and Running Endurance. The 69^<th> Scientific Sessions of the American Diabetes Association 2009
    • Place of Presentation
      Louisiana, USA
    • Year and Date
      2009-06-07
    • Related Report
      2010 Final Research Report
  • [Presentation] Targeted Disruption of Adiponectin Receptor AdipoR2 in Endothelial Cells Reduced PPARgamma and Increased Neointimal Formation.2009

    • Author(s)
      山内敏正, 岩部真人, 岩部美紀, 窪田直人, 植木浩二郎, 門脇孝
    • Organizer
      The 69th Scientific Sessions of the American Diabates Association 2009
    • Place of Presentation
      New Orleans U.S.A.
    • Year and Date
      2009-06-07
    • Related Report
      2009 Annual Research Report
  • [Presentation] AdipoR欠損マウス及び培養細胞を用いた代謝に重要な各組織におけるアディポネクチン受容体を介した細胞内情報伝達の解析2009

    • Author(s)
      山内敏正、岩部真人、岩部美紀、船田雅昭、山口麻美子、窪田直人、植木浩二郎、門脇孝
    • Organizer
      第52回日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2009-05-23
    • Related Report
      2010 Final Research Report 2009 Annual Research Report
  • [Presentation] シンポジウム1:肥満脂肪細胞の病態:肥満脂肪組織とアディポネクチン受容体2008

    • Author(s)
      山内敏正、門脇孝
    • Organizer
      第29回日本肥満学会
    • Place of Presentation
      大分
    • Year and Date
      2008-10-17
    • Related Report
      2010 Final Research Report
  • [Presentation] シンポジウム1肥満脂肪細胞の病態肥満脂肪組織とアディポネクチン受容体2008

    • Author(s)
      山内敏正、門脇孝
    • Organizer
      第29回日本肥満学会
    • Place of Presentation
      大分
    • Year and Date
      2008-10-17
    • Related Report
      2008 Annual Research Report
  • [Presentation] Physiological roles of adiponectin/AdipoRs in skeletal muscle bioenergetics-Disruption of adipoRs resulted in mitochondrial dysfunction in skeletal muscle2008

    • Author(s)
      岩部真人、山内敏正、岩部美紀、植木浩二郎、門脇孝
    • Organizer
      第1回Insulin Resistance in Metabolic Disease Forum
    • Place of Presentation
      大阪
    • Year and Date
      2008-09-20
    • Related Report
      2010 Final Research Report
  • [Presentation] Dynamic functional relay between insulin receptor substrate-1 and -2 in hepatic insulin signaling during fasting and feeding2008

    • Author(s)
      Naoto Kubota、Tetsuya Kubota、Toshimasa Yamauchi、Kohjiro Ueki、Takashi Kadowaki
    • Organizer
      第1回Insulin Resistance in Metabolic Disease Forum
    • Place of Presentation
      大阪
    • Year and Date
      2008-09-20
    • Related Report
      2010 Final Research Report
  • [Presentation] Dynamic functional relay between insulin receptor substrate-1 and -2 in hepatic insulin signaling during fasting and feeding.2008

    • Author(s)
      Naoto Kubota, Tetsuya Kubota, Toshimasa Yamauchi, Kohjiro Ueki, Takashi Kadowaki.
    • Organizer
      第1回Insulin Resistance in Metabolic Disease Forum
    • Place of Presentation
      大阪
    • Year and Date
      2008-09-20
    • Related Report
      2008 Annual Research Report
  • [Presentation] Physiological roles of adiponectin /AdipoRs in skeletal musele bioenergetics -Disruption of adipoRs resulted in mitochon drial dysfunction in skeletal muscle.2008

    • Author(s)
      Masato Iwabu, Toshimasa Yamauchi, Miki Okada-Iwabu, Kohjiro Ueki, Takashi Kadowak
    • Organizer
      第1回InsulinResistance in Metabolic Disease Forum
    • Place of Presentation
      大阪
    • Year and Date
      2008-09-20
    • Related Report
      2008 Annual Research Report
  • [Presentation] シンポジウム6:脂肪組織における炎症とストレス応答Adiponectin Receptors-New Insights in the Pathogenesis of Obesity-linked Insulin Resistance and Metabolic Syndrome-2008

    • Author(s)
      山内敏正
    • Organizer
      第51回日本糖尿病学会年次学術集会
    • Place of Presentation
      東京
    • Year and Date
      2008-05-23
    • Related Report
      2010 Final Research Report
  • [Presentation] シンポジウム6脂肪組織における炎症とストレス応答Adiponectin Receptors-New InsightsinthePathogenesis of Obesity-linked Insulin Resistance and Metabolic Syndrome2008

    • Author(s)
      山内敏正
    • Organizer
      第51回日本糖尿病学会年次学術集会
    • Place of Presentation
      東京
    • Year and Date
      2008-05-23
    • Related Report
      2008 Annual Research Report
  • [Presentation] 2型糖尿病の分子メカニズムと治療戦略2008

    • Author(s)
      山内敏正
    • Organizer
      第51回日本糖尿病学会年次学術集会
    • Place of Presentation
      東京
    • Year and Date
      2008-05-22
    • Related Report
      2010 Final Research Report 2008 Annual Research Report
  • [Presentation] (糖・脂質代謝1-3)アディポネクチン/AdipoRの生理的・病態生理的意義2008

    • Author(s)
      山内敏正
    • Organizer
      第81回日本内分泌学会学術総会
    • Place of Presentation
      青森
    • Year and Date
      2008-05-17
    • Related Report
      2010 Final Research Report
  • [Presentation] アディポネクチン/AdipoRの生理的・病態生理的意義2008

    • Author(s)
      山内敏正
    • Organizer
      第81回日本内分泌学会学術総会
    • Place of Presentation
      青森
    • Year and Date
      2008-05-17
    • Related Report
      2008 Annual Research Report

URL: 

Published: 2008-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi