Creation of new treatment protocol according to the biological prognostic factors for Wilms Tumor
| Project/Area Number |
20390452
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Pediatric surgery
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| Research Institution | Osaka University |
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Principal Investigator |
OUE Takaharu Osaka University, 医学系研究科, 講師 (50314315)
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| Co-Investigator(Kenkyū-buntansha) |
FUKUZAWA Masahiro 大阪大学, 医学系研究科, 教授 (60165272)
MUGISHIMA Hideo 日本大学, 医学部, 教授 (80183648)
KANEKO Yasuhiko 埼玉県立がんセンター, 臨床腫瘍研究所, 所長 (50373387)
NOZAKI Miwako 獨協医科大学, 医学部, 准教授 (30197727)
KOSHINAGA Tsugumichi 日本大学, 医学部, 准教授 (70205376)
OKITA Hajime 国立成育医療センター, 小児血液腫瘍研究部・分子病理研究室, 室長 (50317260)
NAKADATE Hisaya 北里大学, 医学部, 講師 (30306633)
HINOTSU Shiro 京都大学, 医学研究科, 准教授 (80323567)
CHIN Motoaki 日本大学, 医学部, 助教 (50277422)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥19,760,000 (Direct Cost: ¥15,200,000、Indirect Cost: ¥4,560,000)
Fiscal Year 2010: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2009: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2008: ¥12,350,000 (Direct Cost: ¥9,500,000、Indirect Cost: ¥2,850,000)
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| Keywords | Wilms腫瘍 / グループスタディ / 治療プロトコル / 生物学的予後因子 / CCSK / RTK / 両側性腎芽腫 / JWiTS / PTK / 予後因子 / リスク分類 / プロトコール |
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| Research Abstract |
The results of the Japan Wilms Tumor Study group JWiTS-1 was that the OS of patients in the JWiTS-1 study were comparable with the results of other multicenter studies in the USA and Europe. The outcome for patients with nephroblastoma and CCSK was fair. In contrast, the cure rate for those with RTK was not satisfactory. In the patients with bilateral tumor, preservation of renal function was not satisfactory. New treatment strategies are needed for patients with RTK and bilateral Wilms tumor.
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Report
(4 results)
Research Products
(54 results)
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[Journal Article] Outcome of pediatric renal tumor treated using the Japan Wilms Tumor Study-1 (JWiTS-1) protocol : a report from the JWiTS group.2009
Author(s)
Oue T, Fukuzawa M, Okita H, Mugishima H, Horie H, Hata J, Saito M, Nozaki M, Chin M, Nakadate N, Hinotsu S, Koshinaga T, Kaneko Y, Kitano Y, Tanaka Y
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Journal Title
Pediatr Surg Int. 25
Pages: 923-929
NAID
Related Report
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[Journal Article] 日本ウィルムス腫瘍スタディグループ-1登録症例の追跡調査報告2009
Author(s)
大植孝治, 福澤正洋, 大喜多肇, 金子安比古, 北野良博, 越永従道, 齋藤正博, 田中祐吉, 陳基明, 中舘尚也, 野崎美和子, 秦順一, 樋之津史郎, 堀江弘, 麦島秀雄
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Journal Title
小児がん 46(3)
Pages: 349-358
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[Journal Article] 小児がん2009
Author(s)
大植孝治, 福澤正洋, 大喜多肇, 他
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Journal Title
日本ワィルムス腫瘍スタディグループ-1(JWiTS-1)登録症例の追跡調査報告 46
Pages: 349-358
Related Report
Peer Reviewed
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[Presentation] Outcome of Pediatric Renal Tumor Treated With the JWiTS-1 Protocol : A Report From the Japan Wilms Tumor Study (JWITs) Group.2010
Author(s)
Oue T, Fukuzawa M, Koshinaga T, Mugishima H, Nozaki M, Chin M, Nakadate H, Hinotsu S, Kaneko Y, Okita H, et al
Organizer
第26回日本小児がん学会
Place of Presentation
大阪国際会議場
Related Report
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[Presentation] 日本ウィルムス腫瘍シュタディ(JWiTS)-1における晩期障害調査報告2009
Author(s)
中舘尚也, 陳基明, 大植孝治, 越永従道, 野崎美和子, 桶之津史郎, 大喜多肇, 金子安比古, 麦島秀雄, 福澤正洋, 他
Organizer
日本小児がん学会
Place of Presentation
千葉
Related Report
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