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Molecular patho-epidemiological study on oral superficial carcinoma in East Asia regions

Research Project

Project/Area Number 20406029
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section海外学術
Research Field Morphological basic dentistry
Research InstitutionNiigata University

Principal Investigator

CHENG Jun  新潟大学, 医歯学系, 准教授 (40207460)

Co-Investigator(Kenkyū-buntansha) MARUYAMA Satoshi  新潟大学, 医歯学総合病院, 講師 (30397161)
SAKU Takashi  新潟大学, 医歯学系, 教授 (40145264)
IDA Hiroko  新潟大学, 医歯学総合病院, 講師 (60293213)
YAMAZAKI Manabu  新潟大学, 医歯学系, 助教 (10547516)
Project Period (FY) 2008 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥16,770,000 (Direct Cost: ¥12,900,000、Indirect Cost: ¥3,870,000)
Fiscal Year 2011: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2010: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2009: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2008: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Keywords口腔がん / 表在性癌 / 発症機構 / 病理疫学 / 分子病理学 / 扁平上皮癌 / 病理組織学 / 免疫組織化学
Research Abstract

Oral cancers, especially superficial carcinomas, are increasing in number not only in Japan but also Asian countries, which seems to be in parallel to changing of those countries into aging societies. Epidemiologically and molecular pathologically comparing Japanese cases and East Asian cases, we have shown that oral superficial carcinoma is a lesional complex of borderline malignancies including from epithelial dysplasia to micro-invasive carcinoma by establishing pathological diagnostic criteria for carcinoma in-situ, which were biological evidence-based.

Report

(6 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report   Self-evaluation Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (100 results)

All 2012 2011 2010 2009 2008 Other

All Journal Article (44 results) (of which Peer Reviewed: 44 results) Presentation (53 results) Remarks (3 results)

  • [Journal Article] Keratin-10-positive orthokeratotic dysplasia : a new leukoplakia-type precancerous entity of the oral mucosa2012

    • Author(s)
      Kobayashi T, Maruyama S, Abe T, Cheng J, Takagi R, Saku T.
    • Journal Title

      Histopathology

      Volume: (in press) Issue: 5 Pages: 910-920

    • DOI

      10.1111/j.1365-2559.2012.04283.x

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Parenchymal-stromal switching for extracellular matrix production on invasion of oral squamous cell carcinoma2012

    • Author(s)
      Metwaly H, Maruyama S, Yamazaki M, Tsuneki M, Abe T, Jen KY, Cheng J, Saku T.
    • Journal Title

      Human Pathology

      Volume: 43(11) Issue: 11 Pages: 1973-1981

    • DOI

      10.1016/j.humpath.2012.02.006

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Intraepithelially entrapped blood vessels in oral carcinoma in-situ2012

    • Author(s)
      Funayama A, Maruyama S, Yamazaki M, Al-Eryani K, Shingaki S, Saito C, Cheng J, Saku T.
    • Journal Title

      Virchows Archive

      Volume: 460(5) Issue: 5 Pages: 473-480

    • DOI

      10.1007/s00428-012-1224-0

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Loss of keratin 13 in oral carcinoma in situ : a comparative study of protein and gene expression levelsusing paraffin section2012

    • Author(s)
      Ida-Yonemochi H, Maruyam S, Kobayashi T, Yamazaki M, Cheng J, Saku T.
    • Journal Title

      Modern Pathology

      Volume: (in press) Issue: 6 Pages: 784-794

    • DOI

      10.1038/modpathol.2011.218

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Short telomeres in an oral precancerous lesion : Q-FISH analysis of leukoplakia2012

    • Author(s)
      Aida J, Kobayashi T, Saku T, Yamaguchi M, Shimomura N, Nakamura KI, Ishikawa N, Maruyama S, Cheng J, Poon SS, Sawabe M, aida T, Takubo K.
    • Journal Title

      Journal of Oral Pathology & Medicine

      Volume: 41(5) Issue: 5 Pages: 372-378

    • DOI

      10.1111/j.1600-0714.2011.01120.x

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Clinicopathological distinction of two categories of oral squamous cell carcinoma of the tongue: <i>de novo</i> vs. sequential types2012

    • Author(s)
      Saito M, Kobayashi T, Takagi R, Saku T.
    • Journal Title

      Oral Medicine & Pathology

      Volume: 16 Issue: 3+4 Pages: 81-88

    • DOI

      10.3353/omp.16.81

    • NAID

      130004850548

    • ISSN
      1342-0984, 1882-1537
    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Keratin-10-positive orthokeratotic dysplasia : a new leukoplakia-type precancerous entity of the oral mucosa2012

    • Author(s)
      Kobayashi T
    • Journal Title

      Histopathology

      Volume: (in press) Issue: 5 Pages: 974-983

    • DOI

      10.1111/j.1365-2559.2012.04282.x

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Parenchymal-stromal swiching for extracellular matrix production on invasion of oral squamous cell carcinoma2012

    • Author(s)
      Metwaly H
    • Journal Title

      Human Pathology

      Volume: (in press)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Nuclear translocation ofβ-catenin synchronized with loss of E-cadherin in oral epithelial dysplasia with a characteristic two-phase appearance2011

    • Author(s)
      Alvarado CG, Maruyama S, Cheng J, Ida-Yonemochi H, Kobayashi T, Yamazaki M, Takagi R, Saku T.
    • Journal Title

      Histopathology

      Volume: 59(2) Issue: 2 Pages: 283-291

    • DOI

      10.1111/j.1365-2559.2011.03929.x

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Enhancd expression of podoplanin in oral carcinoma in situ and squamous cell carcinomas2011

    • Author(s)
      Funayama A, Cheng J, Maruyama S, Yamazaki M, Kobayashi T, Syafriadi M, Kundu S, Shingaki S, Saito C, Saku T.
    • Journal Title

      Pathobiology

      Volume: 78(3) Issue: 3 Pages: 171-180

    • DOI

      10.1159/000324926

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Emergence of keratin 17 vs. loss of keratin 13 : Their reciprocal immunohistochemical profiles in oral carcinoma in situ2011

    • Author(s)
      Mikami T, Cheng J, Maruyama S, Kobayashi T, Funayama A, Yamazaki M, Adeola HA, Wu L, Shingaki S, Saito C, Saku T.
    • Journal Title

      Oral Oncology

      Volume: 47(6) Issue: 6 Pages: 497-503

    • DOI

      10.1016/j.oraloncology.2011.03.015

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Differential expression of perlecan receptors,α-dystroglycan and integrinβ1, before and after invasion of oral squamous cell carcinoma2011

    • Author(s)
      Ahsan MS, Yamazaki M, Maruyama S, Kobayashi T, Ida-Yonemochi H, Hasegawa M, Adeola HA, Cheng J, Saku T.
    • Journal Title

      Journal of Oral

      Volume: 40(7) Issue: 7 Pages: 552-559

    • DOI

      10.1111/j.1600-0714.2010.00990.x

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Oral cancer in Myanmar : a preliminary survery based on hospital-based cancer registries2011

    • Author(s)
      Oo HN, Myint YY, Maung CN, Oo PS, Cheng J, Maruyama S, Yamazaki M, Yagi M, Sawair FA, Saku T.
    • Journal Title

      Journal of Oral Pathology & Medicine

      Volume: 40(1) Issue: 1 Pages: 20-26

    • DOI

      10.1111/j.1600-0714.2010.00938.x

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Acetic acid treatment for wrinkle-free oral mucosal epithelia in paraffin section preparation2011

    • Author(s)
      Ahsan MS, Maruyama S, Cheng J, Al-Eryani K, Yamazaki M, Hasegawa M, Tsuneki M, Saku T.
    • Journal Title

      Microscopy Research and Technique

      Volume: 74(3) Issue: 3 Pages: 264-268

    • DOI

      10.1002/jemt.20900

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Emergenece of keratin 17 vs.loss of keratin 13 : Their reciprocal immunohistochemical profiles in oral carcinoma in situ.2011

    • Author(s)
      Mikami T, Cheng J, Maruyama S, Kobayashi T, Funayama A, Yamazaki M, Adeola HA, Wu L, Shingaki S, Siato C, Saku T.
    • Journal Title

      Oral Oncology 47(in press)

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Enhanced expression of podoplanin in oral carcinoma in situ and squamous cell carcinomas.2011

    • Author(s)
      Funayama A, Cheng J, Maruyama S, Yamazaki M, Kobayashi T, Syafriadi M, Kundu S, Shingaki S, Saito C, Saku T.
    • Journal Title

      Pathobiology 48(in press)

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Nuclear translocation of β-catenin synchronized with loss of E-cadherin in oral epithelial dysplasia with a charac- terristic two-phase appearance.2011

    • Author(s)
      Alvarado CG, Maruyama S, Cheng J, Ida-Yonemochi H, Kobayashi T, Yamazaki M, Takagi R, Saku T.
    • Journal Title

      Histopathology 58(in press)

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Differential expression of perlecan receptors, α-dystroglycan and integrin β1, before and after invasion of oral squamous cell carcinoma.2011

    • Author(s)
      Ahsan MS, Yamazaki M, Maruyama S, Kobayashi T, Ida-Yonemochi H, Hasegawa M, Adeola HA, Cheng J, Saku T.
    • Journal Title

      Journal of Oral Pathology & Medicine 40(in press)

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Oral cancer in Myanmar : a preliminary survey based on hospital-based cancer registries.2011

    • Author(s)
      Oo HN, Myint YY, Maung CN, Oo PS, Cheng J, Maruyama S, Yamazaki M, Yagi M, Sawair FA, Saku T.
    • Journal Title

      Journal of Oral Pathology & Medicine 40

      Pages: 20-26

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Emergence of keratin 17vs.loss of keratin 13:Their reciprocal immunohistochemical profiles in oral carcinoma in situ2011

    • Author(s)
      Mikami T
    • Journal Title

      Oral Oncology

      Volume: 47 In press

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Enhanced expression of podoplanin in oral carcinoma in situ and squamous cell carcinomas2011

    • Author(s)
      Funayama A
    • Journal Title

      Pathobiology

      Volume: 78 In press

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Nuclear translocation of R-catenin synchronized with loss of E-cadherin in oral epithelialdysplasia with a characteristic two-phase appearance2011

    • Author(s)
      Alvarado CG
    • Journal Title

      Histopathology

      Volume: 58 in press

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Differential expression of perlecan receptors, α-dystroglycan and integrin β1, before andafter invasion of oral squamous cell carcinoma2011

    • Author(s)
      Ahsan MS
    • Journal Title

      Journal of Oral Pathology & Medicine

      Volume: 40 in press

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Oral cancer in Myanmar : apreliminary survey based on hospital-based cancer registries2011

    • Author(s)
      Oo HN
    • Journal Title

      Journal of Oral Pathology & Medicine

      Volume: 40 Pages: 20-26

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Acetic acid treatment for wrinkle-free oral mucosal epithelial in paraffin section preparation2011

    • Author(s)
      Ahsan MS
    • Journal Title

      Microscopy Research and Technique

      Volume: 74 Pages: 264-268

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A Computer-Aided Distinction Method of Borderline Grades of Oral Cancer2010

    • Author(s)
      Sami MM, Saito M, Muramatsu S, Mikami T, Saku T.
    • Journal Title

      IEICE Transactions on Fundamentals of Electronics, Communications and Computer Sciences

      Volume: E93-A Issue: 8 Pages: 1544-1552

    • DOI

      10.1587/transfun.E93.A.1544

    • NAID

      10027368045

    • ISSN
      0916-8508, 1745-1337
    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Histopathological varieties of oral carcinoma in situ : Diagnosis aided by the immunohistochemistry dealing with the second basal cell layer as the proliferating center of oral mucosal epithelia2010

    • Author(s)
      Kobayashi T, Maruyama S, Cheng J, Ida-Yonemochi H, Yagi M, Takagi R, Saku T.
    • Journal Title

      Pathology International

      Volume: 60(3) Issue: 3 Pages: 156-166

    • DOI

      10.1111/j.1440-1827.2009.02499.x

    • NAID

      10029330935

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Twin-pair rete ridge analysis : a computer-aided method for facilitating objective histopathological distinction between epithelial dysplasia and carcinoma in-situ of the oral mucosa2010

    • Author(s)
      Sami MM, Saito M, Muramatsu S, Mikami T, Al-Eryani K, Sawair FA, Eid RA, Cheng J, Kikuchi H, Saku T.
    • Journal Title

      Oral Medicine & Pathology

      Volume: 14(3) Pages: 89-97

    • NAID

      130004509533

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Metastasis-associated genes in oral squamous cell carcinoma and salivary adenoid cystic carcinoma : a differential DNA chip analysis between metastatic and nonmetastatic cell systems2010

    • Author(s)
      Maruyama S, Cheng J, Yamazaki M, Zhou XJ, Zhang ZY, He RG, Saku T.
    • Journal Title

      Cancer Genetics and Cytogenetics

      Volume: 196(1) Pages: 14-22

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Histopathological varieties of oral carcinoma in situ : Diagnosis aided by immunohistoche-mistry dealing with the second basal cell layer as the proliferating center of oral mucosal epithelia.2010

    • Author(s)
      Kobayashi T, Maruyama S, Cheng J, Ida-Yonemochi H, Yagi M, Takagi R, Saku T.
    • Journal Title

      Pathology International 60

      Pages: 156-166

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Histopathological varieties of oral carcinoma in situ : Diagnosis aided by the immunohistochemistry dealing with the second basal cell layer as the proliferating center of oral mucosal epithelia2010

    • Author(s)
      Kobayashi T
    • Journal Title

      Pathology International 60

      Pages: 156-166

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Twin-pair rete ridge analysis : a computer-aided method for facilitating objective histopathological distinction between epithelial dysplasia and carcinoma in-situ of the oral mucosa2010

    • Author(s)
      Mustafa S
    • Journal Title

      Oral Medicine & Pathology 14(3)

      Pages: 89-97

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Metastasis-associated genes in oral squamous cell carcinoma and salivary adenoid cystic carcinoma : a differential DNA chip analysis between metastatic and nonmetastatic cell systems2010

    • Author(s)
      Maruyama S
    • Journal Title

      Cancer Genetics and Cytogenetics 196(1)

      Pages: 14-22

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Matrix metalloproteinase 7 and perlecan in oral epithelial dysplasia and carcinoma in situ : an aid for histopathologic recognition of their cell proliferation centers2009

    • Author(s)
      Tilakaratne WM, Kobayashi T, Ida-Yonemochi H, Swelam W, Yamazaki M, Mikami T, Alvarado CG, Ahsan MS, Maruyama S, Cheng J, Saku T.
    • Journal Title

      Journal of Oral Pathology & Medicine

      Volume: 38(4) Issue: 4 Pages: 348-355

    • DOI

      10.1111/j.1600-0714.2009.00750.x

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Oral solitary fibrous tumor : a cytogenetic analysis of tumor cells in culture with literature review2009

    • Author(s)
      Swelam WM
    • Journal Title

      Cancer Genetics and Cytogenetics 194(2)

      Pages: 75-81

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Establishment and characterization of pleomorphic adenoma cell systems : an in-vitro demonstration of carcinomas arising secondarily from adenomas in the salivary gland2009

    • Author(s)
      Maruyama S
    • Journal Title

      BioMed Central Cancer 9

      Pages: 247-264

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The absence of significant mutational events of the p53 gene in the only two salivary gland tumors possessing radiation-related development risks, mucoepidermoid carcinoma and Warthin tumor2009

    • Author(s)
      Abe M
    • Journal Title

      Oral Medicine & Pathology 13(4)

      Pages: 151-158

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Gingival metastasis of ovarian carcinoma : report of a case and review of the literature2009

    • Author(s)
      Munakata R
    • Journal Title

      International Journal of Oral Maxillofacial Surgery 38(10)

      Pages: 1123-1126

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Keratinocyte growth factor colocalized with perlecan at the site of capsular invasion and vascular involvement in salivary pleomorphic adenomas2009

    • Author(s)
      Maruyama S
    • Journal Title

      Journal of Oral Pathology & Medicine 38(4)

      Pages: 377-385

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Matrix metalloproteinase 7 and perlecan in oral epithelial dysplasia and carcinoma in situ : an aid for histopathologic recognition of their cell proliferation centers2009

    • Author(s)
      Tilakaratne WM
    • Journal Title

      Journal of Oral Pathology & Medicine 38(4)

      Pages: 348-355

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Lymphoepithelial cyst of the parotid gland : its possible histopathogenesis based on clinicopathologic analysis of 64 cases2009

    • Author(s)
      Wu L
    • Journal Title

      Human Pathology 40(5)

      Pages: 683-692

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Matrix metalloproteinase 7 and perlecan in oral epithelial dysplasia and carcinoma in situ : an aid for histopathologic recognition of their cell proliferation centers2008

    • Author(s)
      Tilakaratne WM
    • Journal Title

      Journal of Oral Pathology & Medicine 38

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] FGF7/KGF enhances proliferation but suppresses invasion of adenoid cystic carcinoma cells2008

    • Author(s)
      Maruyama S
    • Journal Title

      Oral Oncology 12(1)

      Pages: 243-250

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Perlecan-rich epithelial lining as a background of proliferative potentials of keratocystic odontogenic tumor2008

    • Author(s)
      Tsuneki M
    • Journal Title

      Journal of Oral Pathology & Medicine 37(5)

      Pages: 287-293

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Presentation] 口腔粘膜上皮内癌と浸潤癌で対比的なパールカン結合増殖因子の発現様式2011

    • Author(s)
      長谷川真弓,程君,丸山智,山崎学,齊藤力,朔敬
    • Organizer
      第56回日本口腔外科学会総会
    • Place of Presentation
      大阪市
    • Related Report
      2011 Final Research Report
  • [Presentation] MFG-E8は口腔扁平上皮癌においてアポトーシス細胞処理と腫瘍進展を促進する2011

    • Author(s)
      山崎学,丸山智,程君,朔敬
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋市
    • Related Report
      2011 Final Research Report
  • [Presentation] Podoplanin regulates the proliferation of oral squamous cell carcinoma cells via its binding to extracellular matrix2011

    • Author(s)
      Tsuneki M, Maruyama S, Yamazaki M, Cheng J, Saku T.
    • Organizer
      The 2011 European Multidisciplinary Cancer Congress
    • Place of Presentation
      Stockholm
    • Related Report
      2011 Final Research Report
  • [Presentation] Hemophagocytosis-induced PAR-2 expression regulates cytoskeletal rearrangement and cell growth of oral squamous cell carcinoma2011

    • Author(s)
      Al-Eryani K, Maruyama S, Yamazaki M, Tsuneki M, Cheng J, Saku T.
    • Organizer
      第22回日本臨床口腔病理学会総会学術大会・第5回アジア口腔病理学会
    • Place of Presentation
      福岡市
    • Related Report
      2011 Final Research Report
  • [Presentation] 口腔扁平上皮癌の浸潤性評価:パールカン免疫陽性間質の立体構築2011

    • Author(s)
      丸山智,島津徳人,工藤朝雄,青葉孝昭,朔敬
    • Organizer
      第100回日本口腔病理学会総会
    • Place of Presentation
      横浜市
    • Related Report
      2011 Final Research Report
  • [Presentation] 口腔扁平上皮癌におけるポドプラニン発現の意義2011

    • Author(s)
      常木雅之,丸山智,山崎学,程君,朔敬
    • Organizer
      第100回日本口腔病理学会総会
    • Place of Presentation
      横浜市
    • Related Report
      2011 Final Research Report
  • [Presentation] MFG-E8は口腔扁平上皮癌においてアポトーシス細胞処理と腫瘍進展を促進する2011

    • Author(s)
      山崎学
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋市・名古屋国際会議場
    • Related Report
      2011 Annual Research Report
  • [Presentation] 口腔粘膜上皮癌と浸潤癌で対比的なパールカン結合増殖因子の発現様式2011

    • Author(s)
      長谷川真弓
    • Organizer
      第56回日本口腔外科学会総会
    • Place of Presentation
      大阪市大阪国際会議場
    • Related Report
      2011 Annual Research Report
  • [Presentation] Podoplanin regulates the proliferation of oral squamous cell carcinoma cells via its binding to extracellular matrix2011

    • Author(s)
      Tsuneki M
    • Organizer
      The 2011 European Multidiscipllnary Cancer Congress
    • Place of Presentation
      Stockholm国際会議場
    • Related Report
      2011 Annual Research Report
  • [Presentation] Hemophagocytosis-induced PAR-2 expression regulates cytoskeletal rearrangement and cell growth of oral squamous cell carcinoma2011

    • Author(s)
      Al-Eryani K
    • Organizer
      第22回日本臨床口腔病理学会・第5回アジア口腔病理学会
    • Place of Presentation
      福岡市・九州大学医学部百年講堂
    • Related Report
      2011 Annual Research Report
  • [Presentation] Intraductal papilloma with peri-luminal extension of the minor salivary gland2011

    • Author(s)
      Cheng J
    • Organizer
      第22回日本臨床口腔病理学会・第5回アジア口腔病理学会
    • Place of Presentation
      福岡市・九州大学医学部百年講堂
    • Related Report
      2011 Annual Research Report
  • [Presentation] 口腔扁平上皮癌におけるMFG-E8の発現:腫瘍進展とアポトーシス細胞処理への関与2011

    • Author(s)
      山崎学
    • Organizer
      第100回日本病理学会総会
    • Place of Presentation
      横浜市・パシフィコ横浜
    • Related Report
      2011 Annual Research Report
  • [Presentation] 口腔扁平上皮癌の浸潤性評価:パールカン免疫陽性間質の立体構築2011

    • Author(s)
      丸山智
    • Organizer
      第100回日本病理学会総会
    • Place of Presentation
      横浜市・パシフィコ横浜
    • Related Report
      2011 Annual Research Report
  • [Presentation] 口腔扁平上皮癌におけるポドプラニン発現の意義2011

    • Author(s)
      常木雅之
    • Organizer
      第100回日本病理学会総会
    • Place of Presentation
      横浜市・パシフィコ横浜
    • Related Report
      2011 Annual Research Report
  • [Presentation] Perlecan-binding growth factors in oral superficial carcinoma2010

    • Author(s)
      Hasegawa M, Cheng J, Maruyama S, Yamazaki M, Saku T.
    • Organizer
      15^<th> Biennial Congress of the International Association of Oral Pathologists
    • Place of Presentation
      Seoul, South Korea
    • Related Report
      2011 Final Research Report
  • [Presentation] Acetic acid treatment for wrinkle free oral mucosal epithelia in paraffin section preparation2010

    • Author(s)
      Ahsan MS, Maruyama S, Cheng J, Al-Eryani K, Yamazaki M, Hasegawa M, Tsuneki M, Saku T.
    • Organizer
      第20回日本口腔粘膜病学会・第21回日本臨床口腔病理学会
    • Place of Presentation
      枚方市
    • Related Report
      2011 Final Research Report
  • [Presentation] 口腔粘膜上皮内癌の病理診断の実践的方法とトランスレーショナル研究視点2010

    • Author(s)
      朔敬
    • Organizer
      第99回日本病理学会総会
    • Place of Presentation
      東京都
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] 正角化型口腔異型上皮における構成細胞のテロメア長と染色体不安定性について:Q-FISH法による解析2010

    • Author(s)
      相田順子,小林孝憲,丸山智,程君,朔敬,泉山七生貴, 他6名
    • Organizer
      第99回日本病理学会総会
    • Place of Presentation
      東京都
    • Related Report
      2011 Final Research Report
  • [Presentation] Perlecan-binding growth factors in oral superficial carcinoma.2010

    • Author(s)
      Hasegawa M, Cheng J, Maruyama S, Yamazaki M, Saku T.
    • Organizer
      15th Biennial Congress of the International Association of Oral Pathologists
    • Place of Presentation
      Seoul, Korea.
    • Related Report
      2010 Self-evaluation Report
  • [Presentation] Epstein-Barr Virus-related lymphoepithelial carcinoma of the salivary gland : Aclinical and molecular pathological analysis in Asia, mainly from the Chinese population2010

    • Author(s)
      Cheng J
    • Organizer
      Global Congress of Chinese Dentists(GCCD 2010)
    • Place of Presentation
      Xiamen, China
    • Related Report
      2010 Annual Research Report
  • [Presentation] Perlecan-binding growth factors in oral superficial carcinoma2010

    • Author(s)
      Hasegawa M
    • Organizer
      15th Biennial Congress of the International Association of Oral Pathologists
    • Place of Presentation
      Seoul, South Korea
    • Related Report
      2010 Annual Research Report
  • [Presentation] 口腔粘膜組織パラフィン切片伸展のための酢酸処理:上皮のシワ防止2010

    • Author(s)
      Ahsan MS
    • Organizer
      第20回日本口腔粘膜病学会・第21回日本臨床口腔病理学会
    • Place of Presentation
      枚方市
    • Related Report
      2010 Annual Research Report
  • [Presentation] 口腔扁平苔癬のリンパ球浸潤域とパールカン沈着:異型上皮との鑑別の試み2010

    • Author(s)
      丸山智
    • Organizer
      第20回日本口腔粘膜病学会・第21回日本臨床口腔病理学会
    • Place of Presentation
      枚方市
    • Related Report
      2010 Annual Research Report
  • [Presentation] 口腔扁平苔癬におけるケラチン17の発現様式:異型上皮との鑑別2010

    • Author(s)
      山崎学
    • Organizer
      第20回日本口腔粘膜病学会・第21回日本臨床口腔病理学会
    • Place of Presentation
      枚方市
    • Related Report
      2010 Annual Research Report
  • [Presentation] New tissue architecture of oral carcinoma in-situ characterized by intraepithelial stroma and intraepithelial blood vessels : Biological evidence for its histopathological diagnosis2009

    • Author(s)
      Saku T.
    • Organizer
      4^<th> Meeting of Asian Society of Oral and Maxillofacial Pathology
    • Place of Presentation
      Beijing, China
    • Related Report
      2011 Final Research Report
  • [Presentation] Hemophagocytosis-related keratinization in squamous cell carcinoma and carcinoma in-situ of the oral mucosa2009

    • Author(s)
      Al-Eryani K, Cheng J, Maruyama S, Yamazaki M, Kobayashi T, Saku T.
    • Organizer
      Joint ECCO 15-34^<th> ESMO Multidisciplinary Congress
    • Place of Presentation
      Berlin, Germany
    • Related Report
      2011 Final Research Report
  • [Presentation] Loss ofβ-catenin and E-cadherin in oral epithelial dysplasia with two-phase appearance2009

    • Author(s)
      Alvarado CG, Cheng J, Ida-Yonemochi H, Maruyama S, Ahsan MS, Takagi R, Saku T.
    • Organizer
      第98回日本病理学会総会
    • Place of Presentation
      京都市
    • Related Report
      2011 Final Research Report
  • [Presentation] 口腔粘膜二層性異型上皮における細胞増殖因子の発現2009

    • Author(s)
      長谷川真弓,丸山智,程君,齊藤力,朔敬
    • Organizer
      第98回日本病理学会総会
    • Place of Presentation
      京都市
    • Related Report
      2011 Final Research Report 2009 Annual Research Report
  • [Presentation] New tissue architecture of oral carcinoma in-situ characterized by intraepithelial stroma and intraepithelial blood vessels.2009

    • Author(s)
      Saku T.
    • Organizer
      4th Biennial Meeting of the Asian Society of Oral and Maxillofacial Pathology
    • Place of Presentation
      Beijing, China.
    • Related Report
      2010 Self-evaluation Report
  • [Presentation] Intracellular deposition of extracellular matrix molecules in calcifying cystic odontogenic tumor : its possible involvement in the histopathologenesis of ghost cells2009

    • Author(s)
      Tsuneki M
    • Organizer
      4th Meeting of Asia Society of Oral and Maxillofacial Pathology
    • Place of Presentation
      Beijing, China
    • Related Report
      2009 Annual Research Report
  • [Presentation] Hemophagocytosis-related keratinization in squamous cell carcinoma and carcinoma in-situ of the oral mucosa2009

    • Author(s)
      Al-Eryani K
    • Organizer
      Joint ECCO15-34th ESMO Multidisciplinary congress
    • Place of Presentation
      Berlin, Germany
    • Related Report
      2009 Annual Research Report
  • [Presentation] 唾液腺多形性腺腫の低酸素環境における増殖機構2009

    • Author(s)
      丸山智
    • Organizer
      第20回日本臨床口腔病理学会総会・学術大会
    • Place of Presentation
      札幌市
    • Related Report
      2009 Annual Research Report
  • [Presentation] 歯原性腫瘍におけるポドプラニンの発現様式2009

    • Author(s)
      常木雅之
    • Organizer
      第20回日本臨床口腔病理学会総会・学術大会
    • Place of Presentation
      札幌市
    • Related Report
      2009 Annual Research Report
  • [Presentation] Histopathological relationship between pseudocysts and true duct-like structures in adenoid cystic carcinoma2009

    • Author(s)
      Ahsan S
    • Organizer
      第20回日本臨床口腔病理学会総会・学術大会
    • Place of Presentation
      札幌市
    • Related Report
      2009 Annual Research Report
  • [Presentation] 脈管分布様式からみたワルチン腫瘍のリンパ性間質2009

    • Author(s)
      阿部達也
    • Organizer
      第98回日本病理学会総会
    • Place of Presentation
      京都市
    • Related Report
      2009 Annual Research Report
  • [Presentation] Keratin pearl formation due to hemoglobin-derived oxidative stress in oral squamous cell carcinoma2009

    • Author(s)
      Al-Eryani K
    • Organizer
      第98回日本病理学会総会
    • Place of Presentation
      京都市
    • Related Report
      2009 Annual Research Report
  • [Presentation] Loss of β-catenin and E-cadherin in oral epithelial dysplasia with two-phase appearance2009

    • Author(s)
      Alvarado C
    • Organizer
      第98回日本病理学会総会
    • Place of Presentation
      京都市
    • Related Report
      2009 Annual Research Report
  • [Presentation] 石灰化嚢胞性歯原性腫瘍の幻影細胞における細胞外基質分子の細胞内蓄積2009

    • Author(s)
      常木雅之
    • Organizer
      第98回日本病理学会総会
    • Place of Presentation
      京都市
    • Related Report
      2009 Annual Research Report
  • [Presentation] Recurrence of leukoplakias as evidencefor malignancy : histopathological varieties oforal carcinoma in-situ2008

    • Author(s)
      Saku T.
    • Organizer
      Asia-pacific congress onOral Cavity Cancer, 12th annual Meeting ofTaiwan Cooperative Oncology Group
    • Place of Presentation
      Taipei, Taiwan
    • Related Report
      2011 Final Research Report
  • [Presentation] 正角化型異型上皮:新しい診断概念の確立とその意義2008

    • Author(s)
      小林孝憲,依田浩子,丸山智,程君,高木律男,齊藤力,朔敬
    • Organizer
      第19回日本臨床口腔病理学会
    • Place of Presentation
      東京都
    • Related Report
      2011 Final Research Report
  • [Presentation] CK17と14-3-3σの共発現が口腔扁平上皮癌で強調される2008

    • Author(s)
      三上俊彦,程君,丸山智,小林孝憲,依田浩子,新垣晋,朔敬
    • Organizer
      第19回日本臨床口腔病理学会
    • Place of Presentation
      東京都
    • Related Report
      2011 Final Research Report
  • [Presentation] Histopathological diagnosis for oralcancer and precancer2008

    • Author(s)
      Saku T.
    • Organizer
      Asian Association of Oraland Maxillofacial Surgeons Lectures andWorkshop
    • Place of Presentation
      Bali, Indonesia
    • Related Report
      2011 Final Research Report
  • [Presentation] Pathologenesis of round-shaped dyskeratosis in oral carcinoma in-sitiu2008

    • Author(s)
      Al-Eryani K, Maruyama S, Cheng J, Saku T.
    • Organizer
      14^<th> Congress of the International Association of Oral Pathologists
    • Place of Presentation
      San Francisco, USA
    • Related Report
      2011 Final Research Report
  • [Presentation] New histopathological criteria for oral borderline malignancies2008

    • Author(s)
      Saku T.
    • Organizer
      First Clinical Pathology Conference or the Chinese and Asian Academy of Oral Pathologists
    • Place of Presentation
      Hangzhou, China
    • Related Report
      2011 Final Research Report
  • [Presentation] 口腔粘膜上皮内癌におけるp53遺伝子変異の解析.ワークショップ「口腔粘膜上皮内癌:診断の科学的根拠」2008

    • Author(s)
      丸山智
    • Organizer
      第97回日本病理学会総会
    • Place of Presentation
      金沢市
    • Related Report
      2011 Final Research Report
  • [Presentation] 口腔粘膜扁平上皮癌・上皮内癌の再発に関する臨床病理学的検討2008

    • Author(s)
      小林孝憲,依田浩子,丸山智,程君,齊藤力,高木律男,朔敬
    • Organizer
      第97回日本病理学会総会
    • Place of Presentation
      金沢市
    • Related Report
      2011 Final Research Report
  • [Presentation] 正角化型異型上皮 : 新しい診断概念の確立とその意義2008

    • Author(s)
      小林孝憲
    • Organizer
      第19回日本臨床口腔病理学会総会
    • Place of Presentation
      東京都
    • Related Report
      2008 Annual Research Report
  • [Presentation] CK17と14-3-38の共発現が口腔粘膜扁平上皮癌で強調される2008

    • Author(s)
      三上俊彦
    • Organizer
      第19回日本臨床口腔病理学会総会
    • Place of Presentation
      東京都
    • Related Report
      2008 Annual Research Report
  • [Presentation] Pathologenesis of round-shaped dyskeratosis in oral carcinoma in-situ2008

    • Author(s)
      Al-Eryani K
    • Organizer
      14^<th> International Congress, International Association of Oral Pathologists
    • Place of Presentation
      San Francisco, USA
    • Related Report
      2008 Annual Research Report
  • [Presentation] FGF7/KGF enhances proliferation but suppresses invasion of adenoid cystic carcinoma cells2008

    • Author(s)
      Maruyama S
    • Organizer
      12^<th> International Congress on Oral Cancer
    • Place of Presentation
      Shanghai, China
    • Related Report
      2008 Annual Research Report
  • [Presentation] 口腔粘膜扁平上皮癌・上皮内癌の再発に関する臨床病理学的検討2008

    • Author(s)
      小林孝憲
    • Organizer
      第97回日本病理学会総会
    • Place of Presentation
      第97回日本病理学会総会
    • Related Report
      2008 Annual Research Report
  • [Presentation] Immunohistochemical characterization of the two-phase appearance of oral precancerous lesion2008

    • Author(s)
      Alvarado C
    • Organizer
      第97回日本病理学会総会
    • Place of Presentation
      金沢市
    • Related Report
      2008 Annual Research Report
  • [Presentation] Comparative expression modes of dystroglycan and perlecan in oral carcinoma in-situ2008

    • Author(s)
      Ahsan S
    • Organizer
      第97回日本病理学会総会
    • Place of Presentation
      金沢市
    • Related Report
      2008 Annual Research Report
  • [Remarks]

    • URL

      http://www.dent.niigata-u.ac.jp/patho/publications/index.html

    • Related Report
      2011 Final Research Report
  • [Remarks]

    • URL

      http://www.dent.niigata-u.ac.jp/patho/index.html

    • Related Report
      2011 Annual Research Report
  • [Remarks]

    • URL

      http://www.dent.niigata-u.ac.jp/patho/publicationsfindex.html

    • Related Report
      2010 Annual Research Report

URL: 

Published: 2008-04-01   Modified: 2016-04-21  

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