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Coordinate frames of MST neurons representing visual motion and smooth pursuit eye movements

Research Project

Project/Area Number 20500351
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Neurophysiology and muscle physiology
Research InstitutionHokkaido University

Principal Investigator

KURKIN Sergey  Hokkaido University, 大学院・医学研究科, 助教 (00344466)

Co-Investigator(Kenkyū-buntansha) FUKUSHIMA Kikuro  北海道大学, 大学院・医学研究科, 教授 (70091486)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2008: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords滑動性追跡眼球運動 / optic flow / MST / 座標表現 / 静的傾斜 / 耳石器 / 最適方向 / サル / 頭部中心座標 / MST野 / 運動視 / 重力 / 耳石 / 単一ニューロン / 日本サル
Research Abstract

To understand coordinate frames representing smooth-pursuit and/or visual motion signals in MST, we compared preferred directions (re monkeys'head/trunk axis) of pursuit and/or visual motion responses of MSTd neurons while upright and during static whole-body roll-tilt. In the majority (80%) of neurons tested, preferred directions of pursuit and/or visual motion responses were similar while upright and during 40°static roll-tilt. Preferred directions of the remaining 20% of neurons were shifted beyond the range expected from ocular counter-rolling. These shifts, however, were still less than half of the expected shift if MST signals are coded in the earth-centered coordinates. These results suggest that smooth-pursuit and/or visual motion signals of MST neurons are coded in the head-centered coordinate.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (53 results)

All 2011 2010 2009 2008 Other

All Journal Article (24 results) (of which Peer Reviewed: 17 results) Presentation (24 results) Book (5 results)

  • [Journal Article] Activity of pursuit-related neurons in Medial Superior Temporal area (MST) during static roll-tilt.2011

    • Author(s)
      Fujiwara K, Akao T, Kurkin S, Fukushima K.
    • Journal Title

      Cerebral Cortex 21

      Pages: 155-165

    • NAID

      120003660575

    • Related Report
      2010 Final Research Report
  • [Journal Article] Neuronal activity in the caudal frontal eye fields of monkeys during memory-based smooth-pursuit eye movements : comparison with the supplementary eye fields.2011

    • Author(s)
      Fukushima J, Akao T, Shichinohe N, Kurkin S, Kaneko CRS, Fukushima K.
    • Journal Title

      Cerebral Cortex 10.1093

    • NAID

      120003260039

    • Related Report
      2010 Final Research Report
  • [Journal Article] Activity of pursuit-related neurons in Medial Superior Temporal area (MST) during static roll-tilt2011

    • Author(s)
      Fujiwara K
    • Journal Title

      Cerebral Cortex

      Volume: 21 Pages: 155-165

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Neuronal activity in the caudal frontal eye fields of monkeys during memory-based smooth-pursuit eye movements : comparison with the supplementary eye fields2011

    • Author(s)
      Fukushima J
    • Journal Title

      Cerebral Cortex

      Volume: (In press,In press)

    • NAID

      120003260039

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Oscillatory eye movements resembling pendular nystagmus in normal juvenile macaques2011

    • Author(s)
      Shichinohe N
    • Journal Title

      Investigative Ophthalmology & Visual Science

      Volume: (In press,In press)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Representation of neck velocity and neck-vestibular interactions in pursuit neurons in the simian frontal eye fields.2010

    • Author(s)
      Fukushima K, Akao T, Saito H, Kurkin S, Fukushima J, Peterson BW.
    • Journal Title

      Cerebral Cortex 20

      Pages: 1195-1207

    • NAID

      120005946612

    • Related Report
      2010 Final Research Report
  • [Journal Article] Representation of neck velocity and neck-vestibular interactions in pursuit neurons in the simian frontal eye fields2010

    • Author(s)
      Fukushima K
    • Journal Title

      Cerebral Cortex

      Volume: 20 Pages: 1195-1207

    • NAID

      120005946612

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Memory and decision-making in the frontal cortex during visual motion-processing for smooth pursuit eye movements.2009

    • Author(s)
      Shichinohe N, Akao T, Kurkin S, Fukushima J, Kaneko CRS, Fukushima K.
    • Journal Title

      Neuron 62

      Pages: 717-732

    • NAID

      120001390974

    • Related Report
      2010 Final Research Report
  • [Journal Article] Eye-pursuit and re-afferent head movement signals carried by pursuit neurons in the caudal part of the frontal eye fields during head-free pursuit.2009

    • Author(s)
      Fukushima K, Kasahara S, Akao T, Kurkin S, Fukushima J, Peterson BW.
    • Journal Title

      Cerebral Cortex 19

      Pages: 263-275

    • Related Report
      2010 Final Research Report
  • [Journal Article] Discharge of pursuit-related neurons in the caudal part of the frontal eye fields in juvenile monkeys with up-down pursuit asymmetry.2009

    • Author(s)
      Kurkin S, Akao T, Fukushima J, Fukushima K.
    • Journal Title

      Experimental Brain Research 193

      Pages: 181-188

    • Related Report
      2010 Final Research Report
  • [Journal Article] Discharge of pursuit-related neurons in the caudal part of the frontal eye fields in juvenile monkeys with up-down pursuit asymmetry2009

    • Author(s)
      Kurkin S
    • Journal Title

      Experimental Brain Research 193

      Pages: 181-188

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Eye-pursuit and re-afferent head movement signals carried by pursuit neurons in the caudal part of the frontal eye fields during head-free pursuit2009

    • Author(s)
      Fukushima K
    • Journal Title

      Cerebral Cortex 19

      Pages: 263-275

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Otolith inputs to pursuit neurons in the frontal eye fields of alert monkeys2009

    • Author(s)
      Akao T
    • Journal Title

      Experimental Brain Research 193

      Pages: 455-466

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Discharge of pursuit neurons in the caudal part of the frontal eye fields during cross-axis vestibular-pursuit training in monkeys2009

    • Author(s)
      Fujiwara K, et al.
    • Journal Title

      Experimental Brain Research 195

      Pages: 229-240

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Memory and decision-making in the frontal cortex during visual motion-processing for smooth pursuit eye movements2009

    • Author(s)
      Shichinohe N, et al.
    • Journal Title

      Neuron 62

      Pages: 717-732

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Relating Neuronal Firing Patterns to Functional Differentiation of Cerebral Cortex2009

    • Author(s)
      Shinomoto S, et al.
    • Journal Title

      PLoS Computational Biology 5

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Representation of neck velocity and neck-vestibular interactions in pursuit neurons in the simian frontal eye fields2009

    • Author(s)
      Fukushima K, et al.
    • Journal Title

      Cerebral Cortex 10.1093/cercor/

    • NAID

      120005946612

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Eye-pursuit and re-afferent head movement signals carried by pursuit neurons in the caudal part of the frontal eye fields during head-free pursuit2009

    • Author(s)
      Fukushisma K, et.al.
    • Journal Title

      Cerebral Cortex 19

      Pages: 263-275

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Discharge of pursuit-related neurons in the caudal part of the frontal eye fields in juvenile monkeys with up-down pursu it asymmetry2009

    • Author(s)
      Kurkin, et.al.
    • Journal Title

      Exp Brain Res 193

      Pages: 181-188

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Otolith inputs to pursuit neurons in the frontal eye fields of alert monkeys2009

    • Author(s)
      Akao, et.al.
    • Journal Title

      Exp Brain Res 193

      Pages: 455-466

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Involvement of the cerebellar dorsal vermis in vergence eye movements in monkeys2008

    • Author(s)
      Nitta T, et.al.
    • Journal Title

      Cerebral Cortex 18

      Pages: 1042-1057

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Oscillatory eye movements resembling pendular nystagmus in normal juvenile macaques.

    • Author(s)
      Shichinohe N, Barnes G, Akao T, Kurkin S, Fukushima J, Kase M, Leigh RJ, Belton T, Fukushima K.
    • Journal Title

      Investigative Ophthalmology and Visual Sciences in press

    • Related Report
      2010 Final Research Report
  • [Journal Article] Discharge of pursuit neurons in the caudal part of the frontal eye fields during cross-axis vestibular-pursuit training in monkeys

    • Author(s)
      Fujiwara, et.al.
    • Journal Title

      Exp Brain Res (印刷中)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Re-afferent head movement signals carried by pursuit neurons of the frontal eye fields during head-movements

    • Author(s)
      Fukushisma K, et.al.
    • Journal Title

      Ann NY Acad Sci (印刷中)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Presentation] Population Responses of Floccular Purkinje Cells During Vergence Pursuit2010

    • Author(s)
      Kurkin S
    • Organizer
      XXVI Barany Society Meeting
    • Place of Presentation
      Reykjavik, Iceland
    • Year and Date
      2010-08-19
    • Related Report
      2010 Annual Research Report
  • [Presentation] Population Responses of Floccular Purkinje Cells During Vergence Pursuit.2010

    • Author(s)
      Kurkin S, Tsubuku T, Akao T, Fukushima J, Fukushima K.
    • Organizer
      XXVI Barany Society Meeting
    • Place of Presentation
      Reykjavik
    • Related Report
      2010 Final Research Report
  • [Presentation] 補足眼野と記憶依存性滑動性追跡眼球運動2009

    • Author(s)
      七戸夏子
    • Organizer
      第89回日本生理学会北海道地方会
    • Place of Presentation
      北海道大学 札幌
    • Year and Date
      2009-09-12
    • Related Report
      2009 Annual Research Report
  • [Presentation] 小脳背側虫部と記憶依存性滑動性追跡眼球運動2009

    • Author(s)
      田代真理
    • Organizer
      第89回日本生理学会北海道地方会
    • Place of Presentation
      北海道大学 札幌
    • Year and Date
      2009-09-12
    • Related Report
      2009 Annual Research Report
  • [Presentation] 前頭眼野追跡眼球運動ニューロンに対する耳石器入力2009

    • Author(s)
      赤尾鉄平
    • Organizer
      第89回日本生理学会北海道地方会
    • Place of Presentation
      北海道大学 札幌
    • Year and Date
      2009-09-12
    • Related Report
      2009 Annual Research Report
  • [Presentation] 耳石器入力による前庭眼反射と視標追跡眼球運動の干渉:前頭眼野および小脳片葉領域追跡眼球運動ニューロンの応答2009

    • Author(s)
      金島基行
    • Organizer
      第89回日本生理学会北海道地方会
    • Place of Presentation
      北海道大学 札幌
    • Year and Date
      2009-09-12
    • Related Report
      2009 Annual Research Report
  • [Presentation] Analsys of Purkinje Cell Discharge of the Cerebellar Floccular Region During 3D-Pursuit2009

    • Author(s)
      クルキンセルゲイ
    • Organizer
      第89回日本生理学会北海道地方会
    • Place of Presentation
      北海道大学 札幌
    • Year and Date
      2009-09-12
    • Related Report
      2009 Annual Research Report
  • [Presentation] MST activity during memory-based smooth pursuit eye movements : comparison with the supplementary eye fields (SEF).2009

    • Author(s)
      Kurkin S, Shichinohe N, Akao T, Fukushima J, Fukushima K.
    • Organizer
      Society for Neuroscience.
    • Place of Presentation
      Chicago
    • Related Report
      2010 Final Research Report
  • [Presentation] Neuronal activity in the caudal frontal eye fields (FEF) : comparison with the supplementary eye fields (SEF) and cerebellar dorsal vermis during memory-based smooth pursuit eye movements.2009

    • Author(s)
      Fukushima J, Akao T, Shichinohe N, Kurkin S, Kaneko CRS, Fukushima K.
    • Organizer
      Society for Neuroscience.
    • Place of Presentation
      Chicago
    • Related Report
      2010 Final Research Report
  • [Presentation] Properties of neck proprioceptive responses of pursuit neurons in the caudal part of the frontal eye fields (FEF) of alert monkeys.2009

    • Author(s)
      Saito H, Akao T, Kurkin S, Fukushima K.
    • Organizer
      36th International congress of physiological Sciences.
    • Place of Presentation
      Kyoto
    • Related Report
      2010 Final Research Report
  • [Presentation] Neural Correlates of memory and decision-making in the supplementary eye fields (SEF) during visual motion-processing for smooth pursuit eye movements.2009

    • Author(s)
      Fukushima K, Shichinohe N, Akao T, Kurkin S, Fukushima J, Kaneko C.
    • Organizer
      19th Annual Meeting of Neural Control of Movement.
    • Place of Presentation
      Big Island, Hawaii
    • Related Report
      2010 Final Research Report
  • [Presentation] MST activity during memory-based smooth pursuit eye movements : comparison with the supplementary eye fields(SEF)2009

    • Author(s)
      Kurkin
    • Organizer
      39^<th> Society for Neuroscience
    • Place of Presentation
      McCormick Place Convention Center, Chicago, USA
    • Related Report
      2009 Annual Research Report
  • [Presentation] Neuronal activity in the caudal frontal eye fields(FEF) : comparison with the supplementary eye fields(SEF)and cerebellar dorsal vermis during memory-based smooth pursuit eye movements2009

    • Author(s)
      Fukushima J
    • Organizer
      39^<th> Society for Neuroscience
    • Place of Presentation
      McCormick Place Convention Center Chicago, USA
    • Related Report
      2009 Annual Research Report
  • [Presentation] Neural Correlates of Memory and Decision-Making in the Supplementary Eye Fields(SEF)During Visual Motion-Processing for Smooth Pursuit Eye Movements2009

    • Author(s)
      Fukushima K
    • Organizer
      19th Annual Meeting of Neural Control of Movement
    • Place of Presentation
      Waikoloa Beach Marriott Resort & Sp, Big Island, Hawaii USA
    • Related Report
      2009 Annual Research Report
  • [Presentation] Properties of neck proprioceptive responses of pursuit neurons in the caudal part of the frontal eye fields(FEF)of alert monkeys2009

    • Author(s)
      Saito H
    • Organizer
      36^<th> International congress of physiological Sciences
    • Place of Presentation
      Kyoto International Conference Center, kyoto
    • Related Report
      2009 Annual Research Report
  • [Presentation] 補足眼野と記憶依存性滑動性追跡眼球運動:作業記憶と運動決定2009

    • Author(s)
      七戸夏子
    • Organizer
      第32回日本神経科学大会
    • Place of Presentation
      名古屋国際会議場 名古屋
    • Related Report
      2009 Annual Research Report
  • [Presentation] ニホンザル前頭眼野後部領域追跡眼球運動に対する耳石器入力2009

    • Author(s)
      赤尾鉄平
    • Organizer
      第32回日本神経科学大会
    • Place of Presentation
      名古屋国際会議場 名古屋
    • Related Report
      2009 Annual Research Report
  • [Presentation] 3次元性追跡眼球運動時の小脳片葉領域Purkinje細胞発射の解析2009

    • Author(s)
      Kurkin S
    • Organizer
      第32回日本神経科学大会
    • Place of Presentation
      名古屋国際会議場 名古屋
    • Related Report
      2009 Annual Research Report
  • [Presentation] 静的傾斜時におけるMST野滑動性追跡眼球運動関連ニューロンの応答2008

    • Author(s)
      藤原圭志, ら
    • Organizer
      第88回日本生理学会北海道地方会
    • Place of Presentation
      北海道大学(札幌市)
    • Year and Date
      2008-09-06
    • Related Report
      2008 Annual Research Report
  • [Presentation] Discharge of pursuit neurons in the caudal part of the frontal eye fields (FEF) in juvenile monkeys with up-down pursuit asymmetry.2008

    • Author(s)
      Fukushima K, Akao T, Kurkin S, Fukushima J.
    • Organizer
      XXV Barany Society Meeting.
    • Place of Presentation
      Kyoto, Japan
    • Related Report
      2010 Final Research Report
  • [Presentation] Activity of pursuit-related neurons in medial superior temporal area (MST) during static roll-tilt.2008

    • Author(s)
      Fujiwara K, Akao T, Kurkin S, Fukushima J, Fukushima K.
    • Organizer
      XXV Barany Society Meeting.
    • Place of Presentation
      Kyoto, Japan
    • Related Report
      2010 Final Research Report
  • [Presentation] Activity of pursuit-related neuron in MST during static roll-ilt2008

    • Author(s)
      藤原圭志, ら
    • Organizer
      第31回日本神経科学大会
    • Place of Presentation
      東京国際フォーラム(東京都)
    • Related Report
      2008 Annual Research Report
  • [Presentation] Activity of pursuit neurons in the caudal part of frontal eyefields (FEF)in juvenile monkeys with up-down pursuitasymmetry2008

    • Author(s)
      赤尾鉄平, ら
    • Organizer
      第31回日本神経科学大会
    • Place of Presentation
      東京国際フォーラム(東京都)
    • Related Report
      2008 Annual Research Report
  • [Presentation] 静的傾斜時におけるMST野滑動性追跡眼球運動関連ニューロンの応答2008

    • Author(s)
      藤原圭志, ら
    • Organizer
      第67回日本めまい平衡医学会総会
    • Place of Presentation
      秋田ビューホテル(秋田市)
    • Related Report
      2008 Annual Research Report
  • [Book] Re-afferent head movement signals carried by pursuit neurons of the frontal eye fields during head-movements.(Ann NY Acad Sci 1164)2009

    • Author(s)
      Fukushima K, Kasahara S, Akao T, Saito H, Kurkin S, Fukushima J, Peterson BW.
    • Related Report
      2010 Final Research Report
  • [Book] Basic and Clinical Aspects of Vertigo and Dizziness, ed by Strupp et al. Ann NY Acad Sci vol 11642009

    • Author(s)
      Fukushima K
    • Total Pages
      508
    • Publisher
      Ann NY Acad Sci
    • Related Report
      2009 Annual Research Report
  • [Book] Prog Brain Res vol.171. Using Eye Movements as an Experimental Probe of Brain Function(Predictive signals in the pursuit area of the monkey frontal eye fields.)(edited by R John Leigh and C Kennard.)(pp.433-440)2008

    • Author(s)
      Fukushima K, Akao T, Shichinohe N, Nitta T, Kurkin S, Fukushima J.
    • Publisher
      Elsevier
    • Related Report
      2010 Final Research Report
  • [Book] Using Eye Movements as an Experimental Probe of Brain Function, Prog Brain Res vol. 171、 edited by R John Leigh and C Kennard2008

    • Author(s)
      Nitta, et.al.
    • Total Pages
      613
    • Publisher
      Elsevier
    • Related Report
      2008 Annual Research Report
  • [Book] Using Eye Movements as an Experimental Probe of Brain Function, Prog Brain Res vol. 171、 edited by R John Leigh and C Kennard2008

    • Author(s)
      Fukushima, et.al.
    • Total Pages
      613
    • Publisher
      Elsevier
    • Related Report
      2008 Annual Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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