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System development of minimally invasive ablation therapy of renal cancer using high-frequency induction technique

Research Project

Project/Area Number 20500423
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Medical systems
Research InstitutionEhime University

Principal Investigator

NAOHARA Takashi  Ehime University, 大学院・理工学研究科, 准教授 (50093935)

Co-Investigator(Kenkyū-buntansha) WATANABE Yuji  愛媛大学, 大学院・医学系研究科, 教授 (20210958)
MAEHARA Tsunehiro  愛媛大学, 大学院・理工学研究科, 教授 (40274302)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Keywords癌治療 / 焼灼療法 / 高周波磁場 / 熱解析シミュレーション / チタン / 磁性体針 / ハイパーサーミア / ラジオ波焼灼療法 / 発熱シミュレーション / 高周波誘導焼灼療法 / 動物実験
Research Abstract

To develop a novel ablation therapy of renal cancer utilizing a high-frequency induction technique, the heating property of the carbon steel rod embedded into the Ti-tube was investigated in a high-frequency output at 300kHz as well as the fabrication of ablation therapy apparatus. In this preliminary experiment, the effect of the inclination angle to the magnetic flux direction was significantly reduced by choosing an optimum Ti-tube thickness. Based on such results, a prototype ablation needle, which is wholly covered with a Ti layer was fabricated for the clinical use. It should be emphasized that this prototype needle possesses a complete non-oriented heating property to the magnetic flux direction.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (21 results)

All 2011 2010 2009 2008

All Journal Article (12 results) (of which Peer Reviewed: 6 results) Presentation (9 results)

  • [Journal Article] Heat Generation Ability in AC Magnetic Field of Needle-type Ti-coated Mild Steel for Ablation Cancer Therapy2011

    • Author(s)
      T.Naohara, H.Aono, H.Hirazawa, T.Maehara, Y.Watanabe, S.Matsutomo
    • Journal Title

      The International Journal for Computation and Mathematics in Electric and Electronic Engineering in press

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] New Heat Generation Ability in AC Magnetic Field for Y_3Fe_5O_<12>-based Powder Material Synthesized by Reverse Coprecipitation Method2011

    • Author(s)
      H.Aono, K.Moritani, T.Naohara, T.Maehara, H.Hirazawa, Y.Watanabe
    • Journal Title

      Materials Letters Vol.65

      Pages: 1454-1456

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Heat Generation Ability in AC Magnetic Field and Their Computer Simulation for Ti Tube Filled with Ferrite Powder2011

    • Author(s)
      H.Aono, T.Naohara, T.Maehara, H.Hirazawa, S.Matsutomo, Y.Watanabe
    • Journal Title

      Journal of Magnetism and Magnetic Materials Vol.323

      Pages: 88-93

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Heat Generation Ability in AC Magnetic Field of Nano MgFe_2O_4-based Ferrite Powder by Bead Milling2011

    • Author(s)
      H.Hirazawa, H.Aono, T.Naohara, T.Maehara, M.Sato, Y.Watanabe
    • Journal Title

      Journal of Magnetism and Magnetic Materials Vol.323

      Pages: 675-680

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Heat Generation Ability in AC Magnetic Field of Nano Sized Ferrite Powder Prepared by Physical Bead Milling for Thermal Coagulation Therapy2010

    • Author(s)
      H.Aono, H.Hirazawa, T.Naohara, T.Maehara, Y.Watanabe
    • Journal Title

      Proceedings of The International Symposium on Heating by Electromagnetic Sources, (Padua, Italy)

      Pages: 483-489

    • Related Report
      2010 Final Research Report
  • [Journal Article] Heat generation ability in AC magnetic field of needle-type Ti-coated mild steel for ablation cancer therapy2010

    • Author(s)
      T.Naohara, et al.
    • Journal Title

      Proceedings of The International Symposium on Heating by Electromagnetic Sources, (Padua, Italy, 2010, 5)

      Pages: 507-511

    • Related Report
      2010 Annual Research Report
  • [Journal Article] Heat generation ability in AC magnetic field and their computer simu-lation for Ti tube filled with ferrite powder2010

    • Author(s)
      H.Aono, et al.
    • Journal Title

      Journal of Magnetism and Magnetic Materials

      Volume: 323 Pages: 88-93

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Computer Simulation of Heat Generation Ability in AC Magnetic Field for Needle-type Materials2009

    • Author(s)
      T.Naohara, H.Aono, T.Maehara, Y.Watanabe, H.Hirazawa, S.Matsutomo
    • Journal Title

      Proceedings of The 6th International Symposium on Electromagnetic Processing of Materials, (Dresden, Germany)

      Pages: 193-196

    • Related Report
      2010 Final Research Report
  • [Journal Article] Computer Simulation of Heat Generation Ability in AC Magnetic Field for Needle-type Materials2009

    • Author(s)
      T.Naohara, et al.
    • Journal Title

      Proceedings of the 6th International Symposium on Electromagnetic Processing of Materials (Dresden, Germany, 2009, 10)

      Pages: 193-196

    • Related Report
      2009 Annual Research Report
  • [Journal Article] Preparation of Fine Ferrite Powder using Bead Mill and its Heat Generation Ability in AC Magnetic Field2009

    • Author(s)
      H.Hirazawa, et al.
    • Journal Title

      Proceedings of the 6th International Symposium on Electromagnetic Processing of Materials (Dresden, Germany, 2009, 10)

      Pages: 189-192

    • Related Report
      2009 Annual Research Report
  • [Journal Article] 金属材料の交流磁場中での発熱とシミュレーション2009

    • Author(s)
      猶原 隆, 他5名
    • Journal Title

      工学ジャーナル(愛媛大学工学部紀要) 8

      Pages: 54-58

    • NAID

      120006524919

    • Related Report
      2008 Annual Research Report
  • [Journal Article] がんの焼灼治療への応用を目的とした発熱磁性材料の開発2008

    • Author(s)
      平澤英之, 他5名
    • Journal Title

      材料の科学と工学(日本材料科学会誌) 45

      Pages: 26-31

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Presentation] ビーズミル粉砕により得られたナノ微粒子の交流磁場中における発熱機構2011

    • Author(s)
      渡部祐輔、青野宏通、猶原隆、前原常弘、渡部祐司、平澤英之
    • Organizer
      日本セラミックス協会2011年年会
    • Place of Presentation
      静岡大学(浜松市)
    • Year and Date
      2011-03-17
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] 逆共沈法により得られたY_3Fe_5O_<12>フェライト粉末の交流磁場中における発熱特性2011

    • Author(s)
      西森忠彦, 他5名
    • Organizer
      日本セラミックス協会2011年年会
    • Place of Presentation
      静岡大学(浜松市)
    • Year and Date
      2011-03-17
    • Related Report
      2010 Annual Research Report
  • [Presentation] ガーネット系Y_3Fe_5O_<12>フェライトのビーズミル粉砕による微粒子化と交流磁場中での発熱特性2011

    • Author(s)
      江原弘規、青野宏通、猶原隆、前原常弘、渡部祐司、平澤英之
    • Organizer
      日本セラミックス協会2011年年会
    • Place of Presentation
      静岡大学(浜松市)
    • Year and Date
      2011-03-16
    • Related Report
      2010 Final Research Report
  • [Presentation] Tiを被覆した炭素鋼丸棒の交流磁場中での発熱特性2010

    • Author(s)
      白井健太郎、猶原隆、青野宏通、前原常弘、平澤英之、松友眞哉
    • Organizer
      日本金属学会第147回秋期講演大会
    • Place of Presentation
      北海道大学(札幌市)
    • Year and Date
      2010-09-27
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] 酸化物磁性体を用いた固形癌の交流磁場誘導焼灼療法の開発-愛媛大学の医理工連携による試み-2009

    • Author(s)
      猶原隆
    • Organizer
      日本セラミックス協会第22回秋季シンポジウム
    • Place of Presentation
      愛媛大学(松山市)
    • Year and Date
      2009-09-17
    • Related Report
      2010 Final Research Report
  • [Presentation] 酸化物磁性体を用いた固形癌の交流磁場誘導焼灼療法の開発 -愛媛大学の医理工連携による試み-2009

    • Author(s)
      猶原隆
    • Organizer
      日本セラミックス協会・第22回秋季シンポジウム
    • Place of Presentation
      愛媛大学(愛媛県)
    • Year and Date
      2009-09-17
    • Related Report
      2009 Annual Research Report
  • [Presentation] 物理的手法によるマグネタイトの粒子径制御と交流磁場中での発熱特性2009

    • Author(s)
      平澤英之, 他5名
    • Organizer
      日本セラミックス協会・第22回秋季シンポジウム
    • Place of Presentation
      愛媛大学(愛媛県)
    • Year and Date
      2009-09-17
    • Related Report
      2009 Annual Research Report
  • [Presentation] 金属管にフェライトを充填した針状材料の誘導加熱シミュレーション2008

    • Author(s)
      小山 貴司, 他5名
    • Organizer
      日本金属学会・2008年秋期(第143回)大会
    • Place of Presentation
      熊本大学
    • Year and Date
      2008-09-24
    • Related Report
      2008 Annual Research Report
  • [Presentation] 金属材料の交流磁場下での発熱とシミュレーション2008

    • Author(s)
      西岡 光輝, 他5名
    • Organizer
      日本金属学会・2008年秋期(第143回)大会
    • Place of Presentation
      熊本大学
    • Year and Date
      2008-09-24
    • Related Report
      2008 Annual Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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