Effects of respiratory function and diaphragm muscle on rats with cervical spinal cord injury
| Project/Area Number |
20500473
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Rehabilitation science/Welfare engineering
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| Research Institution | Kio University |
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Principal Investigator |
IMAGITA Hidetaka Kio University, 健康科学部, 教授 (00412148)
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| Co-Investigator(Kenkyū-buntansha) |
KANEMURA Naohiko 埼玉県立大学, 保健医療福祉学部, 講師 (20379895)
MORIYAMA Hideki 広島大学, 大学院・保健学研究科, 講師 (10438111)
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| Co-Investigator(Renkei-kenkyūsha) |
KANEMURA Naohiko 埼玉県立大学, 保健医療福祉学部, 講師 (20379895)
MORIYAMA Hideki 広島大学, 大学院・保健学研究科, 講師 (10438111)
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| Research Collaborator |
TAKEMOTO Hidenori 県立広島大学, 保健福祉学部, 助教 (10453218)
SHINDOU Hanae 畿央大学, 大学院・健康科学研究科, 博課程前期
NISHIO Syunsuke 畿央大学, 大学院・健康科学研究科, 博課程前期
NISHIKAWA Akira 帝京平成大学, 地域医療学部, 助教 (50614129)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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| Keywords | 頸髄損傷 / 呼吸機能 / 横隔膜筋電図 / 呼吸機能応答 / 横隔膜 / 筋電図 / 呼吸応答 / ラット |
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| Research Abstract |
The purpose of this study is to analyze the effects on the respiratory function and diaphragm muscle of Wistar rats with cervical spinal cord injury. After the operation, the tidal volume of rats with C2 level injury decreased about 5%, and that of rats with C3 level about 25%. The tidal volume of rats with C5 to C7 levels has decreased about 75-95%. In contrast, their diaphragm muscle activity has increased about 10-20%. It could bring out that the respiratory function of patients with cervical spinal cord injury not only affects the activity levels of daily living but also has a significant effect on life support.
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Report
(4 results)
Research Products
(13 results)
