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Effects of respiratory function and diaphragm muscle on rats with cervical spinal cord injury

Research Project

Project/Area Number 20500473
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Rehabilitation science/Welfare engineering
Research InstitutionKio University

Principal Investigator

IMAGITA Hidetaka  Kio University, 健康科学部, 教授 (00412148)

Co-Investigator(Kenkyū-buntansha) KANEMURA Naohiko  埼玉県立大学, 保健医療福祉学部, 講師 (20379895)
MORIYAMA Hideki  広島大学, 大学院・保健学研究科, 講師 (10438111)
Co-Investigator(Renkei-kenkyūsha) KANEMURA Naohiko  埼玉県立大学, 保健医療福祉学部, 講師 (20379895)
MORIYAMA Hideki  広島大学, 大学院・保健学研究科, 講師 (10438111)
Research Collaborator TAKEMOTO Hidenori  県立広島大学, 保健福祉学部, 助教 (10453218)
SHINDOU Hanae  畿央大学, 大学院・健康科学研究科, 博課程前期
NISHIO Syunsuke  畿央大学, 大学院・健康科学研究科, 博課程前期
NISHIKAWA Akira  帝京平成大学, 地域医療学部, 助教 (50614129)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Keywords頸髄損傷 / 呼吸機能 / 横隔膜筋電図 / 呼吸機能応答 / 横隔膜 / 筋電図 / 呼吸応答 / ラット
Research Abstract

The purpose of this study is to analyze the effects on the respiratory function and diaphragm muscle of Wistar rats with cervical spinal cord injury. After the operation, the tidal volume of rats with C2 level injury decreased about 5%, and that of rats with C3 level about 25%. The tidal volume of rats with C5 to C7 levels has decreased about 75-95%. In contrast, their diaphragm muscle activity has increased about 10-20%. It could bring out that the respiratory function of patients with cervical spinal cord injury not only affects the activity levels of daily living but also has a significant effect on life support.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (13 results)

All 2011 2010 2009 Other

All Journal Article (5 results) (of which Peer Reviewed: 5 results) Presentation (6 results) Remarks (2 results)

  • [Journal Article] 慢性閉塞性肺疾患モデルモルモットの横隔膜筋におけるミオシン重鎖表現型の変化2011

    • Author(s)
      今北英高、河合美菜子、宮田浩文
    • Journal Title

      総合リハビリテーション (印刷中)

    • NAID

      40019020682

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 持久性トレーニングが老齢期のラット後肢筋に与える影響2011

    • Author(s)
      西川彰、小野志操、今北英高
    • Journal Title

      総合リハビリテーション 39巻

      Pages: 163-169

    • NAID

      40017649967

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] ラット横隔膜における機能特性および形態特性の加齢変化2010

    • Author(s)
      今北英高、西尾俊亮、西川彰
    • Journal Title

      総合リハビリテーション 38巻

      Pages: 895-871

    • NAID

      40017257216

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Age-related changes in contraction and relaxation of rat diaphragm2009

    • Author(s)
      Imagita H、Tobimatsu Y、Miyata H
    • Journal Title

      Biomed Res 30(6)

      Pages: 337-342

    • NAID

      130004903772

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Age-related changes in contraction and relaxation of rat diaphragm2009

    • Author(s)
      Imagita H., et al.
    • Journal Title

      Biomedical Research Vol.30(6)

      Pages: 337-342

    • NAID

      130004903772

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] Effects of respiratory function on rats with cervical spinal cord injury2011

    • Author(s)
      今北英高
    • Organizer
      The World Confederation for Physical Therapy 2011
    • Place of Presentation
      Amsterdam, Netherlands
    • Year and Date
      2011-06-23
    • Related Report
      2010 Final Research Report
  • [Presentation] 頸髄の損傷レベルにおける呼吸機能および横隔膜筋活動の変化2011

    • Author(s)
      今北英高
    • Organizer
      第46回日本理学療法学術大会
    • Place of Presentation
      宮崎
    • Year and Date
      2011-05-27
    • Related Report
      2010 Final Research Report
  • [Presentation] 高位脊髄損傷ラットにおける呼吸機能への影響2010

    • Author(s)
      今北英高
    • Organizer
      第18回日本運動生理学会
    • Place of Presentation
      鹿児島
    • Year and Date
      2010-08-01
    • Related Report
      2010 Final Research Report
  • [Presentation] 高位脊髄損傷ラットにおける呼吸機能への影響2010

    • Author(s)
      今北英高
    • Organizer
      第18回日本運動生理学会
    • Place of Presentation
      鹿児島大学
    • Year and Date
      2010-08-01
    • Related Report
      2010 Annual Research Report
  • [Presentation] The effects of aging on the functional and metabolic properties of different activity-type muscles2009

    • Author(s)
      Imagita H., et al.
    • Organizer
      2009 AFRM/NIRR/NZRA Rehabilitation Conference
    • Place of Presentation
      ニュージーランド(クイーンズタウン)
    • Year and Date
      2009-07-23
    • Related Report
      2009 Annual Research Report
  • [Presentation] Contractile Properties and Myosin Heavy Chain Isoforms of Skeletal Muscles from young and aged Rat2009

    • Author(s)
      Imagita H., et al.
    • Organizer
      The 5th World Congress of the International Society of Physical and Rehabilitation Medicine
    • Place of Presentation
      トルコ(イスタンブール)
    • Year and Date
      2009-06-14
    • Related Report
      2009 Annual Research Report
  • [Remarks]

    • URL

      http://webinfo.kio.ac.jp/kiol/news_s.asp

    • Related Report
      2010 Annual Research Report
  • [Remarks]

    • URL

      http://webinfo.kio.ac.jp/kio1/view2.asp?msg_no=159

    • Related Report
      2009 Annual Research Report

URL: 

Published: 2008-04-01   Modified: 2016-04-21  

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