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Evaluation of antibacterial properties and biofilm formation of metal materials

Research Project

Project/Area Number 20560656
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Structural/Functional materials
Research InstitutionOsaka City University

Principal Investigator

SATO Yoshihiro  Osaka City University, 大学院・工学研究科, 教授 (00170796)

Co-Investigator(Kenkyū-buntansha) KAWAKAMI Hiroshi  大阪市立大学, 大学院・工学研究科, 准教授 (90305615)
KIKUCHI Yasushi  大阪市立大学, 大学院・工学研究科, 客員教授 (90005405)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2008: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywordsバイオマテリアル / 抗菌機能性材料 / 抗菌機能化金属材料 / バイオフィルム / 微生物腐食 / 新機能材料
Research Abstract

The antibacterial characteristic1s of 21 kinds of bulk metals and 23 kinds of metal ions were clarified to obtain the basic data for the creation of antibacterial metallic materials. Moreover, the biofilm formation behavior formed on the metal surfaces was observed. As a result, antibacterial properties of the bulk metals such as silver, copper and cobalt, etc. are high, and it has been understood that tin, tantalum, and platinum doesn't show antibacterial properties. The similar tendency was shown in the antibacterial examination with the metal ions. It was shown that the formation of the biofilm was restricted on the metal surfaces where antibacterial property was high.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (29 results)

All 2010 2009 2008

All Journal Article (12 results) (of which Peer Reviewed: 10 results) Presentation (15 results) Book (2 results)

  • [Journal Article] Antibacterial properties of nine pure metals : a laboratory using Staphylococcus aureus and Eschelichia coli,Biofouling2010

    • Author(s)
      Y.Miyano, K. kunihiro, S. Kurissery, N. Kanavillil, Y.Sato, Y.Kikuchi
    • Journal Title

      The Journal of Bioadhesion and Biofilm Research Vol.26

      Pages: 851-858

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Bacterial adhesion and initiation of biofilms on the surface of copper containing stainless steel2010

    • Author(s)
      H. Kawakami, K. Kittaka, Y.Sato, Y.Kikuchi
    • Journal Title

      ISIJ International Vol.50

      Pages: 133-138

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Antibacterial properties of nine pure metals : a laboratory using Staphylococcus aureus and Eschelichia coli2010

    • Author(s)
      Y.Miyano, K.kunihiro, S.Kurissery, N.Kanavillil, Y.Sato, Y.Kikuchi
    • Journal Title

      Biofouling, The Journal of Bioadhesion and Biofilm Research

      Volume: 26 Pages: 851-858

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Bacterial adhesion and initiation of biofilms on the surface of copper containing stainless steel2010

    • Author(s)
      H.Kawakami, K.Kittaka, Y.Sato, Y.Kikuchi
    • Journal Title

      ISU International 50

      Pages: 133-138

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 微生物による溶接部の腐食とその対策2009

    • Author(s)
      佐藤嘉洋, 菊地靖志
    • Journal Title

      溶接技術 Vol.57

      Pages: 112-119

    • NAID

      40016864321

    • Related Report
      2010 Final Research Report
  • [Journal Article] 金属材料の抗菌性2009

    • Author(s)
      佐藤嘉洋
    • Journal Title

      高温学会誌 Vol.35

      Pages: 121-125

    • NAID

      10029256538

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 銅および銅合金の抗菌性評価2009

    • Author(s)
      宮野泰征, 小山訓裕, 佐藤嘉洋, 菊地靖志
    • Journal Title

      銅と銅合金 Vol.48

      Pages: 290-299

    • NAID

      40016783391

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 銅および銅合金の抗菌性評価2009

    • Author(s)
      宮野泰征, 小山訓裕, 佐藤嘉洋, 菊地靖志
    • Journal Title

      銅と銅合金 48

      Pages: 290-299

    • NAID

      40016783391

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 金属材料の抗菌性2009

    • Author(s)
      佐藤嘉洋
    • Journal Title

      高温学会誌 35

      Pages: 121-125

    • NAID

      10029256538

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 微生物による溶接部の腐食とその対策2009

    • Author(s)
      佐藤嘉洋, 菊地靖志
    • Journal Title

      溶接技術 57

      Pages: 112-119

    • NAID

      40016864321

    • Related Report
      2009 Annual Research Report
  • [Journal Article] Antibacterial Properties of Metallic Elements for Alloying Evaluated with Application of JIS Z2801 : 20002008

    • Author(s)
      H. Kawakami, K. Yoshida, Y. Nishida, Y.Kikuchi, Y.Sato
    • Journal Title

      ISIJ International Vol.48

      Pages: 1299-1304

    • NAID

      10027030824

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Antibacterial Properties of Metallic Elements For Alloying Evaluated with Application of JIS Z2801:20002008

    • Author(s)
      H. Kawakami, K. Yoshida, Y. Nishida, Y. Kikuchi, Y. Sato
    • Journal Title

      ISIJ International 48

      Pages: 1299-1304

    • NAID

      10027030824

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Presentation] 黄色ブドウ球菌および大腸菌に対するAg, Cu, Zn, Co, Ni, Mn, Au, Pd, Cr, Ti, Sn, Pb, Al,およびV金属イオンの最小殺菌濃度測定2010

    • Author(s)
      堀川直樹, 川上洋司, 菊地靖志, 佐藤嘉洋
    • Organizer
      日本鉄鋼協会第160回秋季講演大会
    • Place of Presentation
      北海道大学
    • Year and Date
      2010-09-26
    • Related Report
      2010 Final Research Report
  • [Presentation] 黄色ブドウ球菌および大腸菌に対するAg, Cu, Zn, Co, Ni, Mn, Au, Pd, Cr, Ti, Sn, Pb, Al,およびV金属イオンめ最小殺菌濃度測定2010

    • Author(s)
      堀川直樹, 川上洋司, 菊地靖志, 佐藤嘉洋
    • Organizer
      日本鉄鋼協会第160回秋季講演大会
    • Place of Presentation
      北海道大学
    • Year and Date
      2010-09-26
    • Related Report
      2010 Annual Research Report
  • [Presentation] Bacterial adhesion to copper alloyed antibacterial stainless steel surfaces2010

    • Author(s)
      H.Kawakami, K. Kittaka, Y.Sato, Y.Kikuchi
    • Organizer
      The 15th International Congress on Marine Corrosion and Fouling
    • Place of Presentation
      Newcastle, England
    • Year and Date
      2010-07-28
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] Ag^+およびCu^<2+>の作用により黄色ブドウ球菌に生じた損傷の透過型電子顕微鏡観察2010

    • Author(s)
      川上洋司, 高岡誠人, 松田孝順, 佐藤嘉洋, 菊地靖志
    • Organizer
      日本金属学会2010年春期大会
    • Place of Presentation
      筑波大学
    • Year and Date
      2010-03-29
    • Related Report
      2010 Final Research Report
  • [Presentation] Transmission electron microscopic study of silver ions induced damage of Staphylococcus aureus2009

    • Author(s)
      川上洋司, 高岡誠人, 佐藤嘉洋, 菊地靖志
    • Organizer
      6th International Symposium on Electron Microscopy in Medicine and Biology 2009
    • Place of Presentation
      Kobe University
    • Year and Date
      2009-09-18
    • Related Report
      2010 Final Research Report
  • [Presentation] Transmission electronmicroscopic study of silver ions induced damage of Staphylococcusaureus2009

    • Author(s)
      H.Kawakami, M.Takaoka, Y.Sato, Y.Kikuchi
    • Organizer
      6th International Symposium on Electron Microscopy in Medicineand Biology 2009
    • Place of Presentation
      Kobe Unversity
    • Year and Date
      2009-09-18
    • Related Report
      2009 Annual Research Report
  • [Presentation] 黄色ブドウ球菌および大腸菌に対するAg^+, Cu^<2+>, Zn^<2+>, Co^<2+>, Ni2^<+>およびMn^<2+>金属イオンの最小殺菌濃度測定2009

    • Author(s)
      堀川直樹, 川上洋司, 菊地靖志, 佐藤嘉洋
    • Organizer
      日本鉄鋼協会第158回秋季講演大会
    • Place of Presentation
      京都大学
    • Year and Date
      2009-09-16
    • Related Report
      2010 Final Research Report
  • [Presentation] 銀イオンの作用によりStaphylococcus aureusに生じた損傷の透過型電子顕微鏡による観察2009

    • Author(s)
      川上洋司, 高岡誠人, 佐藤嘉洋, 菊地靖志
    • Organizer
      日本鉄鋼協会第158回秋季講演大会
    • Place of Presentation
      京都大学
    • Year and Date
      2009-09-16
    • Related Report
      2010 Final Research Report 2009 Annual Research Report
  • [Presentation] 黄色ブドウ球菌および大腸菌に対するAg+, Cu2+, Zn2+, Co2+, Ni2+およびMn2+金属イオンの最小殺菌濃度測定2009

    • Author(s)
      堀川直樹, 川上洋司, 菊地靖志, 佐藤嘉洋
    • Organizer
      日本鉄鋼協会第158回秋季講演大会
    • Place of Presentation
      京都大学
    • Year and Date
      2009-09-16
    • Related Report
      2009 Annual Research Report
  • [Presentation] 銀イオンの作用によりStaphylococcus aureusに生じた損傷の透過型電子顕微鏡による観察2009

    • Author(s)
      川上洋司, 高岡誠人, 佐藤嘉洋, 菊地靖志
    • Organizer
      日本防菌防黴学会第36回年次大会
    • Place of Presentation
      千里ライフセンター(大阪)
    • Year and Date
      2009-09-15
    • Related Report
      2010 Final Research Report
  • [Presentation] 銀イオンの作用によりStaphylococcus aureusに生じた損傷の透過型電子顕微鏡による観察2009

    • Author(s)
      川上洋司, 高岡誠人, 佐藤嘉洋, 菊地靖志
    • Organizer
      日本防菌防黴学会 第36回年次大会
    • Place of Presentation
      千里ライフセンター(大阪)
    • Year and Date
      2009-09-15
    • Related Report
      2009 Annual Research Report
  • [Presentation] 銅および銅合金の抗菌性評価2008

    • Author(s)
      宮野泰征、佐藤嘉洋、菊地靖志
    • Organizer
      第48回銅および銅合金技術研究会講演大会
    • Place of Presentation
      芝浦工業大学豊洲キャンパス
    • Year and Date
      2008-11-23
    • Related Report
      2010 Final Research Report 2008 Annual Research Report
  • [Presentation] 各種金属表面への微生物付着挙動2008

    • Author(s)
      橘高顕治、川上洋司、菊地靖志、佐藤嘉洋
    • Organizer
      日本鉄鋼協会第156回秋季講演大会
    • Place of Presentation
      熊本大学工学部
    • Year and Date
      2008-09-23
    • Related Report
      2010 Final Research Report 2008 Annual Research Report
  • [Presentation] Application of Antibacterial Ability of Metals for Bacterial Control-A Viable Strategy to Control Bacterial Attachment and Microbiolobically Influenced Corrosion-2008

    • Author(s)
      宮野泰征, 佐藤嘉洋, 菊地靖志
    • Organizer
      The 14^<th> International Congress on Marine Corrosion and Fouling
    • Place of Presentation
      神戸国際会議場
    • Year and Date
      2008-07-30
    • Related Report
      2010 Final Research Report
  • [Presentation] Application of Antibacterial Ability of Metals for Bacterial Control-A Viable Strategy to Control Bacterial At tachment and Microbiolobically Influenced Corrosion-2008

    • Author(s)
      Y. Miyano, Y. Sato, Y. Kikuchi
    • Organizer
      The 14^<th> International Congress on Marine Corrosion and Fouling
    • Place of Presentation
      神戸国際会議場
    • Year and Date
      2008-07-30
    • Related Report
      2008 Annual Research Report
  • [Book] 安心・安全・信頼のための抗菌材料2010

    • Author(s)
      兼松秀行、佐藤嘉洋, 他21名
    • Total Pages
      154
    • Publisher
      米田出版
    • Related Report
      2010 Final Research Report 2009 Annual Research Report
  • [Book] 食品安全の正しい常識2009

    • Author(s)
      米虫節夫、佐藤嘉洋, 他41名
    • Total Pages
      187
    • Publisher
      工業調査会
    • Related Report
      2010 Final Research Report 2009 Annual Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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