| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2008: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Research Abstract |
Molecular aspects of the functions of a peptide-gated Na+ channel, FMRFamide-gated Na+ channel (FaNaC), were examined in this study. We found that the position 552 of FaNaC is involved in the activation and the desensitization of the channel, and that the negative electric charge on this position (Asp552) is essential for the inward rectification of the channel current.
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