• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Linkage between Isomerization of Phosphoenzyme Intermediate and Calcium Transport in Sarcoplasmic Reticulum Calcium Pump

Research Project

Project/Area Number 20570102
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Structural biochemistry
Research InstitutionAsahikawa Medical College

Principal Investigator

DAIHO Takashi  Asahikawa Medical College, 医学部, 准教授 (90207267)

Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2008: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
KeywordsCa<^2+>-ATPase / カルシウムポンプ / イオン輸送 / 酵素反応速度論 / 部位特異的変異 / P-type ATPase / 中間体構造アナログ / 小胞体 / Ca^<2+>-ATPase / P-tvpe ATPase / mutation / sarco(endo)plasmic reticulum / analog / phosphoenzyme / calcium / ion transport / Ca^<2+> / Mn^<2+>-ATPase / Golei annaratus / keratinocyte / P-tvoe ATPase
Research Abstract

Ca^<2+> is transported by sarcoplasmic reticulm Ca^<2+>-pump through formation and hydrolysis of phosphoenzyme intermediate (EP) phosphorylated with ATP. Ca^<2+> ions bound to EP from cytoplasm are released into lumen in its isomerization (E1P・Ca_2→E2P). I found structural elements essential for the isomerization, and found a new EP intermediate (E2P・Ca_2) between these two EPs. To perform atomic or other structural analysis, I then developed stable analogs for E1P・Ca_2 and E2P・Ca_2. Furthermore, I have elucidated some new roles of the K+ ion bound to EP during Ca^<2+> transport and the mechanism of pump activation by high-concentration of ATP.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (52 results)

All 2010 2009 2008 Other

All Journal Article (12 results) (of which Peer Reviewed: 10 results) Presentation (39 results) Remarks (1 results)

  • [Journal Article] Ca^<2+> Release to Lumen from ADP-sensitive Phosphoenzyme E1PCa_2 without Bound K^+ of Sarcoplasmic Reticulum Ca^<2+>-ATPase2010

    • Author(s)
      Yamasaki K., Daiho T., Danko S., Suzuki H.
    • Journal Title

      J.Biol.Chem. Vol.285, No.49

      Pages: 38674-38683

    • NAID

      120004606774

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Stable structural analog of Ca^<2+>-ATPase ADP-insensitive phosphoenzyme with occluded Ca^<2+> formed by elongation of A-domain/M1-linker and beryllium fluoride binding2010

    • Author(s)
      Daiho T., Danko S., Yamasaki K., Suzuki H.
    • Journal Title

      J.Biol.Chem. Vol.285, No.32

      Pages: 24538-24547

    • NAID

      120004606780

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Mechanism of Ca^<2+> pump as revealed by mutations, development of stable analogs of phosphorylated intermediates, and their structural analyses2010

    • Author(s)
      Suzuki H., Yamasaki K., Daiho T., Danko S.
    • Journal Title

      Yakugaku Zasshi Vol.130, No.2

      Pages: 179-189

    • NAID

      130000171286

    • Related Report
      2010 Final Research Report
  • [Journal Article] Stable Structural Analog of Ca^<2+>-ATPase ADP-insensitive Phosphoenzyme with Occluded Ca^<2+> Formed by Elongation of A-domain/Ml'-linker and Beryllium Fluoride binding2010

    • Author(s)
      Takashi Daiho, Stefania Danko, Kazuo Yamasaki, Hiroshi Suzuki
    • Journal Title

      Journal of Biological Chemistry

      Volume: 285 Pages: 24538-24547

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Ca^<2+> Release to Lumen from ADP-sensitive Phosphoenzyme E1PCa_2 without Bound K^+ of Sarcoplasmic Reticulum Ca^<2+>-ATPase2010

    • Author(s)
      Kazuo Yamasaki, Takashi Daiho, Stefania Danko, Hiroshi Suzuki
    • Journal Title

      Journal of Biological Chemistry

      Volume: 285 Pages: 38674-38683

    • NAID

      120004606774

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Ca^<2+>ポンプの分子作動機構:部位特異的変異及びリン酸化中間体アナログの開発と構造解析による理解2010

    • Author(s)
      鈴木裕
    • Journal Title

      YAKUGAKU ZASSHI 130

      Pages: 179-189

    • Related Report
      2009 Annual Research Report
  • [Journal Article] Roles of interaction between actuator and nucleotide binding domains of sarco(endo)plasmic reticulum Ca^<2+>-ATPase as revealed by single and swap mutational analyses of serine 186 and glutamate 4392009

    • Author(s)
      Liu X., Daiho T., Yamasaki K., Wang G., Danko S., Suzuki H.
    • Journal Title

      J.Biol.Chem. Vol.284, No.37

      Pages: 25190-25198

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Formation of the stable structural analog of ADP-sensitive phosphoenzyme of Ca^<2+>-ATPase with occluded Ca^<2+> by beryllium fluoride : structural changes during phosphorylation and isomerization2009

    • Author(s)
      Danko S., Daiho T., Yamasaki K., Liu X., Suzuki H.
    • Journal Title

      J.Biol.Chem. Vol.284, No.34

      Pages: 22722-22735

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Formation of the Stable Structural Analog of ADP-sensitive Phosphoenzyme of Ca^<2+>-ATPase with Occluded Ca^<2+> by Beryllium Fluoride : STRUCTURAL CHANGES DURING PHOSPHORYLATION AND ISOMERIZATION2009

    • Author(s)
      Stefania Danko
    • Journal Title

      The Journal of Biological Chemistry 284

      Pages: 22722-22735

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Roles of Interaction between Actuator and Nucleotide Binding Domains of Sarco(endo)plasmic Reticulum Ca^<2+>-ATPase as Revealed by Single and Swap Mutational Analyses of Serine 186 and Glutamate 4392009

    • Author(s)
      Xiaoyu Liu
    • Journal Title

      The Journal of Biological Chemistry 284

      Pages: 25190-25198

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Roles of Tyr122-hydrophobic cluster and K^+ binding in Ca^<2+>-releasing process of ADP-insensitive phosphoenzyme of sarcoplasmic reticulum Ca^<2+>-ATPase2008

    • Author(s)
      Yamasaki K., Wang G., Daiho T., Danko S., Suzuki H.
    • Journal Title

      J.Biol.Chem. Vol.283, No.43

      Pages: 29144-29155

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Roles of Tyr^<122>-hydrophobic Cluster and K^+ Binding in Ca^<2+>-releasing Process of ADP-incensitive Phosnhoenzvme of Sarconlasmic Reticulum Ca^<2+>-ATPase2008

    • Author(s)
      Kazuo Yamasaki
    • Journal Title

      The Journal of Biological Chemistry 283

      Pages: 29144-29155

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Presentation] 筋小胞体Ca^<2+>-ArPaseのリン酸化中間体転換過程における静電的相互作用の役割2010

    • Author(s)
      山崎和生
    • Organizer
      第83回日本生化学会第33回日本分子生物学会年会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-09
    • Related Report
      2010 Annual Research Report
  • [Presentation] 筋小胞体Ca^<2+>-ATPaseのリン酸化中間体転換過程における静電的相互作用の役割2010

    • Author(s)
      山崎和生,大保貴嗣,Stefania Danko,鈴木裕
    • Organizer
      第83回日本生化学会第33回日本分子生物学会年会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-07
    • Related Report
      2010 Final Research Report
  • [Presentation] 筋小胞体Ca^<2+>-ATPaseのリン酸化中間体の異性化と加水分解に影響を及ぼす構造因子2010

    • Author(s)
      大保貴嗣,ダンコ ステファニア,山崎和生,鈴木裕
    • Organizer
      第83回日本生化学会第33回日本分子生物学会年会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-07
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] 筋小胞体Ca^<2+>-ATPaseによるCa^<2+>輸送;細胞質領域アクチュエータードメインと膜貫通ヘリックスを結ぶループの役割2010

    • Author(s)
      大保貴嗣
    • Organizer
      生体エネルギー研究会第36回討論会
    • Place of Presentation
      吹田
    • Year and Date
      2010-11-19
    • Related Report
      2010 Annual Research Report
  • [Presentation] 筋小胞体Ca^<2+>-ATPaseの反応サイクルにおける静電的相互作用の役割とイオン強度依存性との関連2010

    • Author(s)
      山崎和生
    • Organizer
      生体エネルギー研究会第36回討論会
    • Place of Presentation
      吹田
    • Year and Date
      2010-11-19
    • Related Report
      2010 Annual Research Report
  • [Presentation] 筋小胞体Ca^<2+>-ATPaseの反応サイクルにおける静電的相互作用の役割とイオン強度依存性との関連2010

    • Author(s)
      山崎和生、大保貴嗣、Danko Stefania、鈴木裕
    • Organizer
      生体エネルギー研究会第36回討論会
    • Place of Presentation
      大阪
    • Year and Date
      2010-11-18
    • Related Report
      2010 Final Research Report
  • [Presentation] 筋小胞体Ca^<2+>-ATPase によるCa^<2+>輸送;細胞質領域アクチュエータードメインと膜貫通へリックスを結ぶループの役割2010

    • Author(s)
      大保貴嗣、Danko Stefania、山崎和生、鈴木裕
    • Organizer
      生体エネルギー研究会第36回討論会
    • Place of Presentation
      大阪
    • Year and Date
      2010-11-18
    • Related Report
      2010 Final Research Report
  • [Presentation] 筋小胞体Ca^<2+>-ATPaseのリン酸化中間体転換とCa^<2+>輸送;細胞質領域アクチュエータードメインと膜貫通ヘリックスを結ぶループの役割2009

    • Author(s)
      大保貴嗣
    • Organizer
      日本生体エネルギー研究会 第35回討論会
    • Place of Presentation
      旭川
    • Year and Date
      2009-12-20
    • Related Report
      2009 Annual Research Report
  • [Presentation] 筋小胞体Ca^<2+>-ATPaseのE1P-E2P転換とCa^<2+>輸送の共役におけるK^+の役割2009

    • Author(s)
      山崎和生
    • Organizer
      日本生体エネルギー研究会 第35回討論会
    • Place of Presentation
      旭川
    • Year and Date
      2009-12-20
    • Related Report
      2009 Annual Research Report
  • [Presentation] 筋小胞体Ca^<2+>-ATPaseのE1P-E2P転換とCa^<2+>共役におけるK^+の役割2009

    • Author(s)
      山崎和生、大保貴嗣、鈴木裕
    • Organizer
      生体エネルギー研究会第35回討論会
    • Place of Presentation
      旭川
    • Year and Date
      2009-12-18
    • Related Report
      2010 Final Research Report
  • [Presentation] 筋小胞体Ca^<2+>-ATPaseのリン酸化中間体転換とCa^<2+>輸送;細胞質領域アクチュエータードメインと膜貫通へリックスを結ぶループの役割2009

    • Author(s)
      大保貴嗣、Danko Stefania、山崎和生、鈴木裕
    • Organizer
      生体エネルギー研究会第35回討論会
    • Place of Presentation
      旭川
    • Year and Date
      2009-12-18
    • Related Report
      2010 Final Research Report
  • [Presentation] 筋小胞体Ca^<2+>-ATPaseの高濃度ATPによる促進効果について;Actuator/M1-linkerを伸長させた変異体を用いた解析2009

    • Author(s)
      大保貴嗣
    • Organizer
      第82回 日本生化学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2009-10-26
    • Related Report
      2009 Annual Research Report
  • [Presentation] 筋小胞体Ca^<2+>-ATPaseのE1P-E2P転換とCa^<2+>輸送の共役におけるK^+の役割2009

    • Author(s)
      山崎和生
    • Organizer
      第82回 日本生化学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2009-10-26
    • Related Report
      2009 Annual Research Report
  • [Presentation] 筋小胞体Ca^<2+>-ATPaseのE1P-E2P転換とCa^<2+>共役におけるK^+の役割2009

    • Author(s)
      山崎和生、大保貴嗣、鈴木裕
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2009-10-24
    • Related Report
      2010 Final Research Report
  • [Presentation] 高濃度ATPによる筋小胞体リン酸化中間体分解の促進効果について;Actuator/M1-linkerを伸長させた変異体を用いた解析2009

    • Author(s)
      大保貴嗣、山崎和生、ダンコ ステファニア、鈴木裕
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2009-10-24
    • Related Report
      2010 Final Research Report
  • [Presentation] 筋小胞体Ca^<2+>-ATPaseのE1P-E2P転換とCa^<2+>輸送の共役におけるK^+の役割2009

    • Author(s)
      山崎和生、大保貴嗣、鈴木裕
    • Organizer
      日本生化学会 第46回北海道支部例会
    • Place of Presentation
      旭川
    • Year and Date
      2009-07-17
    • Related Report
      2010 Final Research Report
  • [Presentation] 筋小胞体Ca^<2+>-ATPaseのリン酸化中間体転換とCa^<2+>輸送;細胞質領域Actuatorドメインと膜貫通へリックスM1 を結ぶループの役割2009

    • Author(s)
      大保貴嗣、Stefania Danko、山崎和生、鈴木裕
    • Organizer
      日本生化学会 第46回北海道支部例会
    • Place of Presentation
      旭川
    • Year and Date
      2009-07-17
    • Related Report
      2010 Final Research Report
  • [Presentation] 筋小胞体Ca^<2+>-ATPaseのリン酸化中間体転換とCa^<2+>輸送;細胞質領域Actuatorドメインと膜貫通ヘリックスM1を結ぶループの役割2009

    • Author(s)
      大保貴嗣
    • Organizer
      日本生化学会北海道支部例会
    • Place of Presentation
      旭川
    • Year and Date
      2009-07-17
    • Related Report
      2009 Annual Research Report
  • [Presentation] 筋小胞体Ca^<2+>-ATPaseのE1P-E2P転換とCa^<2+>輸送の共役におけるK^+の役割2009

    • Author(s)
      山崎和生
    • Organizer
      日本生化学会北海道支部例会
    • Place of Presentation
      旭川
    • Year and Date
      2009-07-17
    • Related Report
      2009 Annual Research Report
  • [Presentation] Ca^<2+>ポンプの分子作動機構:部位特異的変異およびリン酸化中間体アナログの開発と構造解析による理解2009

    • Author(s)
      鈴木裕、山崎和生、大保貴嗣、Stefania Danko
    • Organizer
      日本薬学会 第129年会
    • Place of Presentation
      京都
    • Year and Date
      2009-03-26
    • Related Report
      2010 Final Research Report
  • [Presentation] 筋小胞体Ca^<2+>-ATPaseのCa^<2+>結合型-リン酸化中間体アナログの安定性におよぼすヌクレオチドの効果2008

    • Author(s)
      大保貴嗣
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会合同大会(BM2007)
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-10
    • Related Report
      2008 Annual Research Report
  • [Presentation] 筋小胞体Ca^<2+>-ATPaseのE2PCa_2におけるTyr^<122>-Hydrophobic clusterの果たす役割について2008

    • Author(s)
      山崎和生
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会合同大会(BMB2007)
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-10
    • Related Report
      2008 Annual Research Report
  • [Presentation] Roles of interactions between Actuator-and Nucleotide Binding-domains of Ca^<2+>-ATPase2008

    • Author(s)
      Xiaoyu Liu
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会合同大会(BMB2007)
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-10
    • Related Report
      2008 Annual Research Report
  • [Presentation] Roles of interactions between Actuator- and Nucleotide binding- domains of sarcoplasmic reticulum Ca^<2+>-ATPase2008

    • Author(s)
      Xiaoyu Ryu, Takashi Daiho, Kazuo Yamasaki, Stefania Danko, Hiroshi Suzuki
    • Organizer
      第81回日本生化学会第31回日本分子生物学会年会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-09
    • Related Report
      2010 Final Research Report
  • [Presentation] 筋小胞体Ca^<2+>-ATPaseのE2PCa2におけるTyr122-Hydrophobic clusterの果たす役割について2008

    • Author(s)
      山崎和生、王国麗、大保貴嗣、鈴木裕
    • Organizer
      第81回日本生化学会第31回日本分子生物学会年会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-09
    • Related Report
      2010 Final Research Report
  • [Presentation] 筋小胞体Ca^<2+>-ATPaseのCa^<2+>結合型-リン酸化中間体アナログの安定性に及ぼすヌクレオチドの効果2008

    • Author(s)
      大保貴嗣、Stefania Danko、山崎和生、鈴木裕
    • Organizer
      第81回日本生化学会第31回日本分子生物学会年会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-09
    • Related Report
      2010 Final Research Report
  • [Presentation] 筋小胞体Ca^<2+>-ATPaseのP-Nヒンジ領域に存在する荷電側鎖の役割と一価イオンの影響2008

    • Author(s)
      山崎和生、大保貴嗣、鈴木裕
    • Organizer
      生体エネルギー研究会第34回討論会
    • Place of Presentation
      東京
    • Year and Date
      2008-11-08
    • Related Report
      2010 Final Research Report
  • [Presentation] Ca^<2+>ポンプの輸送機構-部位特異的変異およびリン酸化中間体アナログの開発と構造解析による理解2008

    • Author(s)
      鈴木裕、大保貴嗣、山崎和生、劉暁宇、Danko Stefania
    • Organizer
      生体エネルギー研究会第34回討論会
    • Place of Presentation
      東京
    • Year and Date
      2008-11-08
    • Related Report
      2010 Final Research Report
  • [Presentation] 筋小胞体Ca^<2+>-ATPaseのリン酸化中間体の転換及びCa^<2+>輸送におよぼすヌクレオチドの顕著な効果2008

    • Author(s)
      大保貴嗣、山崎和生、鈴木裕
    • Organizer
      生体エネルギー研究会第34回討論会
    • Place of Presentation
      東京
    • Year and Date
      2008-11-08
    • Related Report
      2010 Final Research Report
  • [Presentation] 筋小胞体Ca^<2+>-ATPaseのP-Nドメインヒンジ領域に存在する荷電側鎖の役割と一価イオンの影響2008

    • Author(s)
      山崎和生
    • Organizer
      日本生体エネルギー研究会
    • Place of Presentation
      東京
    • Year and Date
      2008-11-08
    • Related Report
      2008 Annual Research Report
  • [Presentation] 筋小胞体Ca^<2+>-ATPaseのリン酸化中間体の転換およびCa^<2+>輸送におよほすヌクレオチドの顕著な効果2008

    • Author(s)
      大保貴嗣
    • Organizer
      日本生体エネルギー研究会
    • Place of Presentation
      東京
    • Year and Date
      2008-11-07
    • Related Report
      2008 Annual Research Report
  • [Presentation] Mechanism of Ca^<2+> pump as revealed by mutations, development of analogs of nhosnhorvlated intermediates, and their structural analysis2008

    • Author(s)
      鈴木裕
    • Organizer
      日本生体エネルギー研究会
    • Place of Presentation
      東京
    • Year and Date
      2008-11-07
    • Related Report
      2008 Annual Research Report
  • [Presentation] Roles of A -ddmain and its linkers of sarco(endo)plasmic reticulum Ca^<2+> pump for nrocessine the nhosnhorvlated intermediates and Ca^<2+> release2008

    • Author(s)
      Hiroshi Suzuki
    • Organizer
      12^<th> International ATPase Conference ; Na, K-ATPase and Related Transport ATPases of P-type
    • Place of Presentation
      Denmark
    • Year and Date
      2008-08-06
    • Related Report
      2008 Annual Research Report
  • [Presentation] Roles of the A domain and its linkers of sarco(endo)plasmic reticulum Ca^<2+> pump for processing the phosphorylated intermediates and Ca^<2+> release2008

    • Author(s)
      HIroshi Suzuki, Takashi Daiho, Kazuo Yamasaki, Xiaoyu Liu, Stefania Danko
    • Organizer
      12th International ATPase Conference Na,K-ATPase and Related Transport ATPases of P-type : Structures, Mechanisms, and Roles in Health and Disease
    • Place of Presentation
      Aarhus (Denmark)
    • Related Report
      2010 Final Research Report
  • [Presentation] Roles of Tyr122-Hydrophobic cluster and K^+ binding in Ca^<2+>-releasing Process of ADP-insensitive Phosphoenzyme of Sarcoplasmic Reticulum Ca^<2+>-ATPase2008

    • Author(s)
      Kazuo Yamasaki, Guoli Wang, Takashi Daiho, Hiroshi Suzuki
    • Organizer
      12th International ATPase Conference Na,K-ATPase and Related Transport ATPases of P-type : Structures, Mechanisms, and Roles in Health and Disease
    • Place of Presentation
      Aarhus (Denmark)
    • Related Report
      2010 Final Research Report
  • [Presentation] Critical Role of Glu40-Ser48 Loop Linking Actuator Domain and First Transmembrane Helix of Ca^<2+>-ATPase in Ca^<2+> Deocclusion and Release from ADP-insensitive Phosphoenzyme2008

    • Author(s)
      Takashi Daiho, Kazuo Yamasaki, Stefania Danko, Hiroshi Suzuki
    • Organizer
      12th International ATPase Conference Na,K-ATPase and Related Transport ATPases of P-type : Structures, Mechanisms, and Roles in Health and Disease
    • Place of Presentation
      Aarhus (Denmark)
    • Related Report
      2010 Final Research Report
  • [Presentation] ATP2C1 is specifically localized in the basal layer of normal epidermis and its depletion triggers differentiation of keratinocytes via manganese starvation in the Golgi apparatus2008

    • Author(s)
      Masaki Yoshida
    • Organizer
      The international investigative Dermatology 2008
    • Place of Presentation
      京都
    • Related Report
      2008 Annual Research Report
  • [Presentation] Critical role of Glua ^<40>-Ser^<48> loop linking actuator domain and first transmembrane helix of Ca^<2+>-ATPase in Ca2+ deocclusion and release from ADP-insensitive phosphoenzyme2008

    • Author(s)
      Daiho Takashi
    • Organizer
      12^<th> International ATPase Conference ; Na, K-ATPase and Related Transport ATPases of P-type
    • Place of Presentation
      Denmark
    • Related Report
      2008 Annual Research Report
  • [Presentation] Roles of Tyr^<122>-hydrophobic Cluster and K^+ Binding in Ca^<2+>-releasing Process of ADP-insensitive Phosphoenzyme of Sarcoplasmic Reticulum Ca^<2+>-ATPase2008

    • Author(s)
      Kazuo Yamasaki
    • Organizer
      12^<th> International ATPase Conference ; Na, K-ATPase and Related, Transport ATPases of P-type
    • Place of Presentation
      Denmark
    • Related Report
      2008 Annual Research Report
  • [Remarks]

    • URL

      http://www.asahikawa-med.ac.jp/dept/mc/biochem2/

    • Related Report
      2010 Annual Research Report

URL: 

Published: 2008-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi