Analysis of the novel quorum-sensing mechanism observed in thermo-tolerant evolution process
| Project/Area Number |
20570225
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Evolutionary biology
|
|---|
| Research Institution | Toho University |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
WATANABE Soichiro 東邦大学, 理学部, 准教授 (10287550)
|
|---|
| Project Period (FY) |
2008 – 2010
|
| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2008: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
|
|---|
| Keywords | 大腸菌 / 耐熱進化 / クオラムセンシング / 相互作用 |
|---|
| Research Abstract |
Intercellular interaction observed in thermo-tolerant evolution process of E. coli was quorum sensing like growth regulation. This interaction was mainly driven by lactic acid as quorumon. This interaction appeared strongly in early phase in 45 degree adaptation and decreased evolution time-dependently.
|
Report
(4 results)
Research Products
(50 results)
-
[Journal Article] Transition from positive to neutral in mutation fixation along with continuing rising fitness in thermal adaptive evolution2010
Author(s)
T. Kishimoto, L. Iijima, M. Tatsumi, N. Ono, A. Oyake, T. Hashimoto, M. Matsuo, M. Okubo, S. Suzuki, K. Mori, A. Kashiwagi, C. Furusawa, Bei-Wen Ying, T. Yomo
-
Journal Title
Related Report
Peer Reviewed
-
-
[Journal Article] Transition from positive to neutral in mutation fixation along with continuing rising fitness in thermal adaptive evolution2010
Author(s)
T.Kishimoto, L.Iijima, M.Tatsumi, N.Ono, A.Oyake, T.Hashimoto, M.Matsuo, Me Okubo, S.Suzuki, K Mori, A.Kashiwagi, C.Furusawa, Bei-Wen Ying, T.Yomo
-
Journal Title
Related Report
Peer Reviewed
-
-
[Journal Article] Crystal structure of a chaperone complex that contributes to the assembly of yeast 20S Proteasome.2008
Author(s)
H. Yashiroda, T. Mizushima, K. Okamoto, T. Kameyama, H. Hayashi, T. Kishimoto, S. Niwa, M. Kasahara, E. Kurimoto, E. Sakata, K. Takagi, A. Suzuki, Y. Hirano, S. Murata, K. Kato, T. Yamane, K. Tanaka
-
Journal Title
Nature structural & molecular biology 15
Pages: 228-236
Related Report
Peer Reviewed
-
-
-
-
-
-
-
-
-
[Presentation] 高温適応進化における大腸菌の発現パターンの再編2010
Author(s)
北原和樹, 岸本利彦, 小野直亮, 古澤力, 鈴木真吾, インベイウェン, 四方哲也
Organizer
BMB2010(第33回日本分子生物学会年会・第83回日本生化学会大会合同大会)
Place of Presentation
神戸ポートアイランド(兵庫県)
Year and Date
2010-12-09
Related Report
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
